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Research ArticleArticle

Effect of Pregnancy on Ankylosing Spondylitis: A Case-Control Study

Nai Lee Lui, Nigil Haroon, Adele Carty, Hua Shen, Richard J. Cook, Sutha Shanmugarajah, Dafna D. Gladman and Robert D. Inman
The Journal of Rheumatology August 2011, jrheum.101174; DOI: https://doi.org/10.3899/jrheum.101174
Nai Lee Lui
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Nigil Haroon
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Adele Carty
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Hua Shen
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Richard J. Cook
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Sutha Shanmugarajah
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Dafna D. Gladman
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Robert D. Inman
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Abstract

Objective To evaluate the effect of pregnancy on ankylosing spondylitis (AS).

Methods Our study aimed to determine the severity of back pain and stiffness pre-, during, and postpartum in patients with AS and controls, and corresponding extraarticular symptoms.

Results Nineteen female patients with AS (35 pregnancies) and 33 controls (77 pregnancies) were studied. Improvement in pain was reported in 51% of AS patients, predominantly in the first trimester, with significant improvement in pain than stiffness. In both groups, pain worsened in later stages, likely secondary to biomechanical loading. Postpartum pain scores in AS returned to prepartum levels in general.

Conclusion Pregnancy does not substantially aggravate disease activity or severity in AS.

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The Journal of Rheumatology
Vol. 50, Issue 9
1 Sep 2023
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Effect of Pregnancy on Ankylosing Spondylitis: A Case-Control Study
Nai Lee Lui, Nigil Haroon, Adele Carty, Hua Shen, Richard J. Cook, Sutha Shanmugarajah, Dafna D. Gladman, Robert D. Inman
The Journal of Rheumatology Aug 2011, jrheum.101174; DOI: 10.3899/jrheum.101174

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Effect of Pregnancy on Ankylosing Spondylitis: A Case-Control Study
Nai Lee Lui, Nigil Haroon, Adele Carty, Hua Shen, Richard J. Cook, Sutha Shanmugarajah, Dafna D. Gladman, Robert D. Inman
The Journal of Rheumatology Aug 2011, jrheum.101174; DOI: 10.3899/jrheum.101174
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