Skip to main content

Main menu

  • Home
  • Content
    • First Release
    • Current
    • Archives
    • Collections
    • Audiovisual Rheum
    • 50th Volume Reprints
  • Resources
    • Guide for Authors
    • Submit Manuscript
    • Payment
    • Reviewers
    • Advertisers
    • Classified Ads
    • Reprints and Translations
    • Permissions
    • Meetings
    • FAQ
    • Policies
  • Subscribers
    • Subscription Information
    • Purchase Subscription
    • Your Account
    • Terms and Conditions
  • About Us
    • About Us
    • Editorial Board
    • Letter from the Editor
    • Duncan A. Gordon Award
    • Privacy/GDPR Policy
    • Accessibility
  • Contact Us
  • JRheum Supplements
  • Services

User menu

  • My Cart
  • Log In

Search

  • Advanced search
The Journal of Rheumatology
  • JRheum Supplements
  • Services
  • My Cart
  • Log In
The Journal of Rheumatology

Advanced Search

  • Home
  • Content
    • First Release
    • Current
    • Archives
    • Collections
    • Audiovisual Rheum
    • 50th Volume Reprints
  • Resources
    • Guide for Authors
    • Submit Manuscript
    • Payment
    • Reviewers
    • Advertisers
    • Classified Ads
    • Reprints and Translations
    • Permissions
    • Meetings
    • FAQ
    • Policies
  • Subscribers
    • Subscription Information
    • Purchase Subscription
    • Your Account
    • Terms and Conditions
  • About Us
    • About Us
    • Editorial Board
    • Letter from the Editor
    • Duncan A. Gordon Award
    • Privacy/GDPR Policy
    • Accessibility
  • Contact Us
  • Follow Jrheum on BlueSky
  • Follow jrheum on Twitter
  • Visit jrheum on Facebook
  • Follow jrheum on LinkedIn
  • Follow jrheum on YouTube
  • Follow jrheum on Instagram
  • Follow jrheum on RSS
Research ArticleArticle

Effect of Pregnancy on Ankylosing Spondylitis: A Case-Control Study

Nai Lee Lui, Nigil Haroon, Adele Carty, Hua Shen, Richard J. Cook, Sutha Shanmugarajah, Dafna D. Gladman and Robert D. Inman
The Journal of Rheumatology August 2011, jrheum.101174; DOI: https://doi.org/10.3899/jrheum.101174
Nai Lee Lui
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Nigil Haroon
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Adele Carty
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Hua Shen
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Richard J. Cook
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sutha Shanmugarajah
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Dafna D. Gladman
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Robert D. Inman
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Info & Metrics
  • References
  • PDF
Next
Loading

Abstract

Objective To evaluate the effect of pregnancy on ankylosing spondylitis (AS).

Methods Our study aimed to determine the severity of back pain and stiffness pre-, during, and postpartum in patients with AS and controls, and corresponding extraarticular symptoms.

Results Nineteen female patients with AS (35 pregnancies) and 33 controls (77 pregnancies) were studied. Improvement in pain was reported in 51% of AS patients, predominantly in the first trimester, with significant improvement in pain than stiffness. In both groups, pain worsened in later stages, likely secondary to biomechanical loading. Postpartum pain scores in AS returned to prepartum levels in general.

Conclusion Pregnancy does not substantially aggravate disease activity or severity in AS.

Next
Back to top

In this issue

The Journal of Rheumatology
Vol. 52, Issue 6
1 Jun 2025
  • Table of Contents
  • Table of Contents (PDF)
  • Index by Author
  • Editorial Board (PDF)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word about The Journal of Rheumatology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Effect of Pregnancy on Ankylosing Spondylitis: A Case-Control Study
(Your Name) has forwarded a page to you from The Journal of Rheumatology
(Your Name) thought you would like to see this page from the The Journal of Rheumatology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Effect of Pregnancy on Ankylosing Spondylitis: A Case-Control Study
Nai Lee Lui, Nigil Haroon, Adele Carty, Hua Shen, Richard J. Cook, Sutha Shanmugarajah, Dafna D. Gladman, Robert D. Inman
The Journal of Rheumatology Aug 2011, jrheum.101174; DOI: 10.3899/jrheum.101174

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

 Request Permissions

Share
Effect of Pregnancy on Ankylosing Spondylitis: A Case-Control Study
Nai Lee Lui, Nigil Haroon, Adele Carty, Hua Shen, Richard J. Cook, Sutha Shanmugarajah, Dafna D. Gladman, Robert D. Inman
The Journal of Rheumatology Aug 2011, jrheum.101174; DOI: 10.3899/jrheum.101174
del.icio.us logo Twitter logo Facebook logo  logo Mendeley logo
  • Tweet Widget
  •  logo
Bookmark this article

Jump to section

  • Article
  • Info & Metrics
  • References
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • A Systematic Review of Clinical Trial Designs and Outcome Measures in Sjögren Disease Randomized Controlled Trials
  • Frailty and Associated Outcomes in Patients With Vasculitis
  • Implementation and Evaluation of a Virtual Rheumatology Training Program in East Africa
Show more Articles

Similar Articles

Content

  • First Release
  • Current
  • Archives
  • Collections
  • Audiovisual Rheum
  • COVID-19 and Rheumatology

Resources

  • Guide for Authors
  • Submit Manuscript
  • Author Payment
  • Reviewers
  • Advertisers
  • Classified Ads
  • Reprints and Translations
  • Permissions
  • Meetings
  • FAQ
  • Policies

Subscribers

  • Subscription Information
  • Purchase Subscription
  • Your Account
  • Terms and Conditions

More

  • About Us
  • Contact Us
  • My Alerts
  • My Folders
  • Privacy/GDPR Policy
  • RSS Feeds
The Journal of Rheumatology
The content of this site is intended for health care professionals.
Copyright © 2025 by The Journal of Rheumatology Publishing Co. Ltd.
Print ISSN: 0315-162X; Online ISSN: 1499-2752
Powered by HighWire