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Research ArticleArticle

Etanercept Compared to Intraarticular Corticosteroid Injection in Rheumatoid Arthritis: Double-blind, Randomized Pilot Study

Christian H. Roux, Veronique Breuil, Laure Valerio, Nicolas Amoretti, Olivier Brocq, Christine Albert, Christian Grisot, Yacine Allam, Patrick Chevalier, Christian Pradier and Lianna Euller-Ziegler
The Journal of Rheumatology March 2011, jrheum.100828; DOI: https://doi.org/10.3899/jrheum.100828
Christian H. Roux
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Veronique Breuil
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Laure Valerio
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Nicolas Amoretti
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Olivier Brocq
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Christine Albert
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Christian Grisot
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Yacine Allam
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Patrick Chevalier
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Christian Pradier
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Lianna Euller-Ziegler
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Abstract

Objective To compare etanercept (anti-tumor necrosis factor-α) with intraarticular (IA) corticosteroid injections to treat rheumatoid arthritis (RA).

Methods Patients with RA who had persistent monoarthritis received etanercept or IA corticosteroid injections. Efficacy was compared at Weeks 4 and 24.

Results Thirty-four patients were included (8 dropped out). Mean age was 58.8 years. No difference between groups was found at Weeks 4 or 24, but both groups showed significant improvement at Weeks 4 and 24 compared to baseline.

Conclusion Etanercept and IA steroid injections resulted in significant improvement at Week 4 that persisted to Week 24. There was no significant difference in outcome between the groups.

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The Journal of Rheumatology: 52 (7)
The Journal of Rheumatology
Vol. 52, Issue 7
1 Jul 2025
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Etanercept Compared to Intraarticular Corticosteroid Injection in Rheumatoid Arthritis: Double-blind, Randomized Pilot Study
Christian H. Roux, Veronique Breuil, Laure Valerio, Nicolas Amoretti, Olivier Brocq, Christine Albert, Christian Grisot, Yacine Allam, Patrick Chevalier, Christian Pradier, Lianna Euller-Ziegler
The Journal of Rheumatology Mar 2011, jrheum.100828; DOI: 10.3899/jrheum.100828

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Etanercept Compared to Intraarticular Corticosteroid Injection in Rheumatoid Arthritis: Double-blind, Randomized Pilot Study
Christian H. Roux, Veronique Breuil, Laure Valerio, Nicolas Amoretti, Olivier Brocq, Christine Albert, Christian Grisot, Yacine Allam, Patrick Chevalier, Christian Pradier, Lianna Euller-Ziegler
The Journal of Rheumatology Mar 2011, jrheum.100828; DOI: 10.3899/jrheum.100828
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