Article Figures & Data
Figures
- Figure 1.
Fulfillment of individual domains by intervention over the (A) first 6 months and (B) last 6 months. PtGA: patient global assessment.
- Figure 2.
Fulfillment of remission definitions over 6-monthly periods.
Tables
- Table 1.
Six-monthly fulfillment of the 2016 preliminary gout remission definition and the simplified gout remission definition according to randomized group.
Six-monthly Fulfillment of the 2016 Preliminary Definition Colchicine,
n = 100Placebo,
n = 100OR (95% CI)a P Months 1-6 3 (3) 4 (4) 0.62 (0.12-3.18) 0.57 Months 7-12 4 (4) 14 (14) 0.29 (0.09-0.90) 0.03 Six-monthly Fulfillment of the Simplified Definition Colchicine,
n = 100Placebo,
n = 100OR (95% CI)a P Months 1-6 7 (7) 12 (12) 0.61 (0.22-1.68) 0.34 Months 7-12 14 (14) 28 (28) 0.41 (0.20-0.85) 0.02 ↵a Participants in placebo group were used as the reference. OR: odds ratio.
- Table 2.
Comparison of month 12 BIPQ scores between those who fulfilled and did not fulfill the 2016 preliminary gout remission definition in the final 6 months of the trial (months 7-12).
Belief Type BIPQ Itema Fulfilled,
n = 18,
mean (95% CI)Not Fulfilled,
n = 182,
mean (95% CI)Mean Difference
(95% CI)P Consequence How much does gout affect your life?
(10 = severely affects life)0.86 (−0.53 to 2.26) 2.18 (1.75 to 2.63) 1.32 (−0.10 to 2.75) 0.07 Timeline How long do you think your gout will continue?
(10 = will continue forever)8.78 (6.84 to 10.73) 7.58 (6.99 to 8.16) −1.20 (−3.22 to 0.80) 0.25 Personal control How much control do you feel you have over your
gout? (10 = extreme amount)9.02 (7.86 to 10.19) 8.12 (7.70 to 8.54) −0.90 (−2.12 to 0.32) 0.15 Treatment
controlHow much do you think your treatment can
help your gout? (10 = extremely helpful)8.96 (7.95 to 9.98) 8.81 (8.42 to 9.21) −0.15 (−1.21 to 0.91) 0.77 Identity How much do you experience symptoms from
your gout? (10 = many severe symptoms)0.89 (−0.21 to 2.00) 2.10 (1.72 to 2.50) 1.21 (0.05 to 2.37) 0.04 Concern How concerned are you about your gout?
(10 = extremely concerned)1.20 (−0.34 to 2.73) 3.40 (2.84 to 3.96) 2.20 (0.63 to 3.77) 0.01 Understanding How well do you feel you understand your gout?
(10 = very clearly)8.70 (7.71 to 9.69) 8.35 (8.00 to 8.71) −0.35 (−1.38 to 0.67) 0.48 Emotional
responseHow much does your gout affect you emotionally?
(10 = extremely affected)0.97 (−0.39 to 2.33) 2.10 (1.65 to 2.55) 1.13 (−0.22 to 2.48) 0.08 ↵a Each question was rated on a 0-10 Likert scale. BIPQ: Brief Illness Perception Questionnaire.
- Table 3.
Comparison of month 12 BIPQ scores between those who fulfilled and did not fulfill the simplified gout remission definition in the final 6 months of the trial (months 7-12).
Belief Type BIPQ Itema Fulfilled,
n = 42,
mean (95% CI)Not Fulfilled,
n = 158,
mean (95% CI)Mean Difference
(95% CI)P Consequence How much does gout affect your life?
(10 = severely affects life)0.84 (−0.01 to 1.70) 2.39 (1.91 to 2.87) 1.55 (0.61 to 2.48) 0.002 Timeline How long do you think your gout will
continue? (10 = will continue forever)8.03 (6.94 to 9.14) 7.49 (6.84 to 8.15) −0.54 (−1.77 to 0.68) 0.39 Personal control How much control do you feel you have
over your gout? (10 = extreme amount)8.71 (7.94 to 9.48) 8.07 (7.60 to 8.53) −0.64 (−1.50 to 0.22) 0.15 Treatment control How much do you think your treatment
can help your gout? (10 = extremely helpful)9.07 (8.38 to 9.75) 8.77 (8.33 to 9.20) −0.30 (−1.04 to 0.44) 0.44 Identity How much do you experience symptoms
from your gout? (10 = many severe symptoms)0.80 (−0.01 to 1.62) 2.29 (1.86 to 2.71) 1.49 (0.60 to 2.37) 0.002 Concern How concerned are you about your gout?
(10 = extremely concerned)1.61 (0.53 to 2.69) 3.59 (2.97 to 4.20) 1.98 (0.83 to 3.12) 0.002 Understanding How well do you feel you understand your
gout? (10 = very clearly)8.65 (7.97 to 9.33) 8.35 (7.96 to 8.74) −0.30 (−1.04 to 0.45) 0.43 Emotional response How much does your gout affect you
emotionally? (10 = extremely affected)1.29 (0.42 to 2.16) 2.19 (1.70 to 2.69) 0.90 (−0.06 to 1.86) 0.07 ↵a Each question was rated on a 0-10 Likert scale. BIPQ: Brief Illness Perception Questionnaire.
Data Supplement
