Article Figures & Data
Tables
Isolated
NeutropeniaNeutropenia/
LymphopeniaP Patients, n 35 135 Neutropenia severity Severe 6 (17.1) 24 (17.8) 0.93 Mild/moderate 29 (82.9) 111 (82.2) Age at index date, yrs, mean (SD) 38.5 (12.1) 38.7 (12.7) 0.91 Disease duration, yrs, mean (SD) 8.8 (8.6) 10.4 (8.9) 0.33 Female sex 32 (91.4) 121 (89.6) 0.75 Black race 19 (54.3) 45 (33.3) 0.02* SLEDAI-2K score, mean (SD) 4.0 (3.8) 5.2 (4.5) 0.17 Low C or anti-dsDNA 23 (65.7) 91 (67.4) 0.85 Azathioprine 3 (8.6) 37 (27.4) 0.02* Cyclophosphamide 0 (0) 0 (0) – Methotrexate 0 (0) 7 (5.2) 0.17 MMF 7 (20) 21 (15.6) 0.53 Bacterial infection 1 (2.9) 5 (3.7) 0.81 Viral infection 2 (5.7) 6 (4.4) 0.75 Values are presented as n (%) unless indicated otherwise.
↵* P < 0.05. C: complement; MMF: mycophenolate mofetil; SLEDAI-2K: Systemic Lupus Erythematosus Disease Activity Index 2000.
- Table 2.
Infection rate within 1 year in patients with no neutropenia, isolated neutropenia, and combined neutropenia/lymphopenia.
No Neutropenia,
n = 1385Isolated Neutropenia,
n = 31Neutropenia/Lymphopenia,
n = 128Infection rate, n (%) 243 (17.6) 2 (6.5)* 28 (21.9) Cohort sizes are smaller than in Table 1 because some patients had no further visits.
↵* P < 0.05 comparing infection rate with lymphopenia/neutropenia group; no other pairwise difference was found.
