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Research ArticlePsoriatic Arthritis
Open Access

Secukinumab in United States Biologic-Naïve Patients With Psoriatic Arthritis: Results From the Randomized, Placebo-Controlled CHOICE Study

Tien Nguyen, Melvin Churchill, Robert Levin, Guillermo Valenzuela, Joseph F. Merola, Alexis Ogdie, Ana-Maria Orbai, Jose U. Scher, Arthur Kavanaugh, Farid Kianifard, Chauncy Rollins, Renato Calheiros and Olivier Chambenoit
The Journal of Rheumatology August 2022, 49 (8) 894-902; DOI: https://doi.org/10.3899/jrheum.210912
Tien Nguyen
1T. Nguyen, MD, First OC Dermatology, Irvine, California;
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Melvin Churchill
2M. Churchill, MD, Arthritis Center of Nebraska, Lincoln, Nebraska;
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  • ORCID record for Melvin Churchill
Robert Levin
3R. Levin, MD, Clinical Research of West Florida, Inc., Clearwater, Florida, and University of South Florida, Tampa, Florida;
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Guillermo Valenzuela
4G. Valenzuela, MD, Integral Rheumatology & Immunology Specialists, Plantation, Florida, USA;
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Joseph F. Merola
5J.F. Merola, MD, Department of Dermatology and Medicine, Division of Rheumatology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts;
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  • ORCID record for Joseph F. Merola
Alexis Ogdie
6A. Ogdie, MD, MSCE, Department of Medicine/Rheumatology and Department of Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania;
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  • ORCID record for Alexis Ogdie
Ana-Maria Orbai
7A.M. Orbai, MD, MHS, Division of Rheumatology, Psoriatic Arthritis Program, Johns Hopkins University School of Medicine, Baltimore, Maryland;
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  • ORCID record for Ana-Maria Orbai
Jose U. Scher
8J.U. Scher, MD, Division of Rheumatology, New York University School of Medicine and NYU Langone Orthopedic Hospital, New York, New York;
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Arthur Kavanaugh
9A. Kavanaugh, MD, Division of Rheumatology, Allergy and Immunology, Department of Medicine, University of California, San Diego, La Jolla, California;
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Farid Kianifard
10F. Kianifard, PhD, C. Rollins, MS, R. Calheiros, MD, O. Chambenoit, PhD, Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA.
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Chauncy Rollins
10F. Kianifard, PhD, C. Rollins, MS, R. Calheiros, MD, O. Chambenoit, PhD, Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA.
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Renato Calheiros
10F. Kianifard, PhD, C. Rollins, MS, R. Calheiros, MD, O. Chambenoit, PhD, Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA.
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Olivier Chambenoit
10F. Kianifard, PhD, C. Rollins, MS, R. Calheiros, MD, O. Chambenoit, PhD, Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA.
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Article Information

vol. 49 no. 8 894-902
DOI 
https://doi.org/10.3899/jrheum.210912
PubMed 
35428722

Published By 
The Journal of Rheumatology
Print ISSN 
0315-162X
Online ISSN 
1499-2752
History 
  • Accepted for publication April 5, 2022
  • Published online July 28, 2022.

Article Versions

  • Latest version (April 15, 2022 - 04:00).
  • Latest version (June 1, 2022 - 04:00).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2022 by the Journal of Rheumatology This is an Open Access article, which permits use, distribution, and reproduction, without modification, provided the original article is correctly cited and is not used for commercial purposes.

Author Information

  1. Tien Nguyen1,
  2. Melvin Churchill2,
  3. Robert Levin3,
  4. Guillermo Valenzuela4,
  5. Joseph F. Merola5,
  6. Alexis Ogdie6,
  7. Ana-Maria Orbai7,
  8. Jose U. Scher8,
  9. Arthur Kavanaugh9,
  10. Farid Kianifard10,
  11. Chauncy Rollins10,
  12. Renato Calheiros10 and
  13. Olivier Chambenoit10
  1. 1T. Nguyen, MD, First OC Dermatology, Irvine, California;
  2. 2M. Churchill, MD, Arthritis Center of Nebraska, Lincoln, Nebraska;
  3. 3R. Levin, MD, Clinical Research of West Florida, Inc., Clearwater, Florida, and University of South Florida, Tampa, Florida;
  4. 4G. Valenzuela, MD, Integral Rheumatology & Immunology Specialists, Plantation, Florida, USA;
  5. 5J.F. Merola, MD, Department of Dermatology and Medicine, Division of Rheumatology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts;
  6. 6A. Ogdie, MD, MSCE, Department of Medicine/Rheumatology and Department of Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania;
  7. 7A.M. Orbai, MD, MHS, Division of Rheumatology, Psoriatic Arthritis Program, Johns Hopkins University School of Medicine, Baltimore, Maryland;
  8. 8J.U. Scher, MD, Division of Rheumatology, New York University School of Medicine and NYU Langone Orthopedic Hospital, New York, New York;
  9. 9A. Kavanaugh, MD, Division of Rheumatology, Allergy and Immunology, Department of Medicine, University of California, San Diego, La Jolla, California;
  10. 10F. Kianifard, PhD, C. Rollins, MS, R. Calheiros, MD, O. Chambenoit, PhD, Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA.
  1. Address correspondence to Dr. T.Q. Nguyen, First OC Dermatology, 17305 Von Karman Avenue, Suite 107, Irvine, CA 92614, USA. Email: tiennguyenmd82{at}gmail.com.

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The Journal of Rheumatology
Vol. 49, Issue 8
1 Aug 2022
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Secukinumab in United States Biologic-Naïve Patients With Psoriatic Arthritis: Results From the Randomized, Placebo-Controlled CHOICE Study
Tien Nguyen, Melvin Churchill, Robert Levin, Guillermo Valenzuela, Joseph F. Merola, Alexis Ogdie, Ana-Maria Orbai, Jose U. Scher, Arthur Kavanaugh, Farid Kianifard, Chauncy Rollins, Renato Calheiros, Olivier Chambenoit
The Journal of Rheumatology Aug 2022, 49 (8) 894-902; DOI: 10.3899/jrheum.210912

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Secukinumab in United States Biologic-Naïve Patients With Psoriatic Arthritis: Results From the Randomized, Placebo-Controlled CHOICE Study
Tien Nguyen, Melvin Churchill, Robert Levin, Guillermo Valenzuela, Joseph F. Merola, Alexis Ogdie, Ana-Maria Orbai, Jose U. Scher, Arthur Kavanaugh, Farid Kianifard, Chauncy Rollins, Renato Calheiros, Olivier Chambenoit
The Journal of Rheumatology Aug 2022, 49 (8) 894-902; DOI: 10.3899/jrheum.210912
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Keywords

BIOLOGICALS
IL-17 inhibitors
PSORIASIS
PSORIATIC ARTHRITIS

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