Post SARS-CoV-2 Vaccine Chilblains-like Lesions

To the Editor:

We would like to share ideas on the article, “A Case of Chilblains-like Lesions Post SARS-CoV-2 Vaccine?”¹ Meara et al reported a female case and concluded, “The chilblains-like lesions suggest that she had an antibody response from either 1 vaccine dose or a previous PCR-negative COVID-19 [coronavirus disease 2019] infection.”¹ The existence of antibodies might or might not explain occurrence of chilblains-like lesions. An exact pathomechanism is unclear. In addition to abnormal immune response, the process might be related to an increased blood viscosity after vaccination.² After COVID-19 vaccination, there might be an occurrence of a hyperviscosity problem,² which is reported as an uncommon cause of chilblains-like lesions.³

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