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Research ArticleOsteoarthritis
Open Access

WOMAC Meaningful Within-patient Change: Results From 3 Studies of Tanezumab in Patients With Moderate-to-severe Osteoarthritis of the Hip or Knee

Philip G. Conaghan, Robert H. Dworkin, Thomas J. Schnitzer, Francis Berenbaum, Andrew G. Bushmakin, Joseph C. Cappelleri, Lars Viktrup and Lucy Abraham
The Journal of Rheumatology June 2022, 49 (6) 615-621; DOI: https://doi.org/10.3899/jrheum.210543
Philip G. Conaghan
1P.G. Conaghan, MB BS, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Biomedical Research Centre, Leeds, UK;
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  • ORCID record for Philip G. Conaghan
Robert H. Dworkin
2R.H. Dworkin, PhD, University of Rochester, Rochester, New York, USA;
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Thomas J. Schnitzer
3T.J. Schnitzer, MD, PhD, Northwestern University, Evanston, Illinois, USA;
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  • ORCID record for Thomas J. Schnitzer
Francis Berenbaum
4F. Berenbaum, MD, PhD, Sorbonne Université, Paris, France;
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  • ORCID record for Francis Berenbaum
Andrew G. Bushmakin
5A.G. Bushmakin, MS, J.C. Cappelleri, PhD, Pfizer Inc, Groton, Connecticut, USA;
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Joseph C. Cappelleri
5A.G. Bushmakin, MS, J.C. Cappelleri, PhD, Pfizer Inc, Groton, Connecticut, USA;
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  • ORCID record for Joseph C. Cappelleri
Lars Viktrup
6L. Viktrup, MD, PhD, Eli Lilly and Co., Indianapolis, Indiana, USA;
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Lucy Abraham
7L. Abraham, MSc, CPsychol, Pfizer Ltd, Surrey, UK.
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  • For correspondence: Lucy.Abraham{at}pfizer.com
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Article Information

vol. 49 no. 6 615-621
DOI 
https://doi.org/10.3899/jrheum.210543
PubMed 
35232805

Published By 
The Journal of Rheumatology
Print ISSN 
0315-162X
Online ISSN 
1499-2752
History 
  • Accepted for publication February 9, 2022
  • Published online June 1, 2022.

Article Versions

  • Latest version (March 1, 2022 - 04:00).
  • Latest version (May 2, 2022 - 10:00).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2022 by the Journal of Rheumatology This is an Open Access article, which permits use, distribution, and reproduction, without modification, provided the original article is correctly cited and is not used for commercial purposes.

Author Information

  1. Philip G. Conaghan1,
  2. Robert H. Dworkin2,
  3. Thomas J. Schnitzer3,
  4. Francis Berenbaum4,
  5. Andrew G. Bushmakin5,
  6. Joseph C. Cappelleri5,
  7. Lars Viktrup6 and
  8. Lucy Abraham7⇑
  1. 1P.G. Conaghan, MB BS, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Biomedical Research Centre, Leeds, UK;
  2. 2R.H. Dworkin, PhD, University of Rochester, Rochester, New York, USA;
  3. 3T.J. Schnitzer, MD, PhD, Northwestern University, Evanston, Illinois, USA;
  4. 4F. Berenbaum, MD, PhD, Sorbonne Université, Paris, France;
  5. 5A.G. Bushmakin, MS, J.C. Cappelleri, PhD, Pfizer Inc, Groton, Connecticut, USA;
  6. 6L. Viktrup, MD, PhD, Eli Lilly and Co., Indianapolis, Indiana, USA;
  7. 7L. Abraham, MSc, CPsychol, Pfizer Ltd, Surrey, UK.
  1. Address correspondence to L. Abraham, Pfizer Ltd, 1-G Walton Oaks, Dorking Road, Walton on the Hill, Tadworth, Surrey KT20 7NS, UK. Email: Lucy.Abraham{at}pfizer.com.

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The Journal of Rheumatology
Vol. 49, Issue 6
1 Jun 2022
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WOMAC Meaningful Within-patient Change: Results From 3 Studies of Tanezumab in Patients With Moderate-to-severe Osteoarthritis of the Hip or Knee
Philip G. Conaghan, Robert H. Dworkin, Thomas J. Schnitzer, Francis Berenbaum, Andrew G. Bushmakin, Joseph C. Cappelleri, Lars Viktrup, Lucy Abraham
The Journal of Rheumatology Jun 2022, 49 (6) 615-621; DOI: 10.3899/jrheum.210543

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WOMAC Meaningful Within-patient Change: Results From 3 Studies of Tanezumab in Patients With Moderate-to-severe Osteoarthritis of the Hip or Knee
Philip G. Conaghan, Robert H. Dworkin, Thomas J. Schnitzer, Francis Berenbaum, Andrew G. Bushmakin, Joseph C. Cappelleri, Lars Viktrup, Lucy Abraham
The Journal of Rheumatology Jun 2022, 49 (6) 615-621; DOI: 10.3899/jrheum.210543
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Keywords

CLINICAL TRIALS
OSTEOARTHRITIS
OUTCOMES
PAIN

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  • Association of Periarticular Subchondral Bone Mineral Density With the Presence and Progression of Knee Pain: Data From the Osteoarthritis Initiative
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