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Research ArticleOther Arthritides
Open Access

COVID-19 Vaccination Uptake Among Individuals With Immune-mediated Inflammatory Diseases in Ontario, Canada, Between December 2020 and October 2021: A Population-based Analysis

Jessica Widdifield, Lihi Eder, Simon Chen, Jeffrey C. Kwong, Carol Hitchon, Diane Lacaille, J. Antonio Aviña-Zubieta, Lawrence W. Svenson and Sasha Bernatsky
The Journal of Rheumatology May 2022, 49 (5) 531-536; DOI: https://doi.org/10.3899/jrheum.211148
Jessica Widdifield
1J. Widdifield, PhD, Assistant Professor, Institute of Health Policy, Management & Evaluation, University of Toronto, Sunnybrook Research Institute, Holland Bone & Joint Program, Toronto, and ICES, Toronto, Ontario;
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Lihi Eder
2L. Eder, MD, PhD, Associate Professor, University of Toronto, and Women’s College Research Institute, Women’s College Hospital, Toronto, Ontario;
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Simon Chen
3S. Chen, MPH, ICES, Toronto, Ontario;
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Jeffrey C. Kwong
4J.C. Kwong, MD, MSc, FRCPC, Professor, Department of Family and Community Medicine, Faculty of Medicine, and Dalla Lana School of Public Health, University of Toronto, ICES, Toronto, and Public Health Ontario, Toronto, Ontario;
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Carol Hitchon
5C. Hitchon, MD, MSc, Associate Professor, Department of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba;
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Diane Lacaille
6D. Lacaille, MD, MHSc, FRCPC, Professor, J.A. Aviña-Zubieta, MD, PhD, FRCPC, Associate Professor, Division of Rheumatology, Department of Medicine, University of British Columbia, and Arthritis Research Canada, Vancouver, British Columbia;
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J. Antonio Aviña-Zubieta
6D. Lacaille, MD, MHSc, FRCPC, Professor, J.A. Aviña-Zubieta, MD, PhD, FRCPC, Associate Professor, Division of Rheumatology, Department of Medicine, University of British Columbia, and Arthritis Research Canada, Vancouver, British Columbia;
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Lawrence W. Svenson
7L.W. Svenson, PhD, Analytics and Performance Reporting Branch, Alberta Health, Edmonton, Division of Preventive Medicine, University of Alberta, Edmonton, School of Public Health, University of Alberta, Edmonton, and Department of Community Health Sciences, University of Calgary, Calgary, Alberta;
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Sasha Bernatsky
8S. Bernatsky, MD, FRCPC, PhD, Professor, Divisions of Rheumatology and Clinical Epidemiology, Department of Medicine, McGill University Health Centre, Montreal, Quebec, Canada.
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    Figure 1.

    Cumulative percentage of each population with at least 1 dose by October 3, 2021.

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    Figure 2.

    Cumulative percentage of each population with 2 doses by October 3, 2021.

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    Table 1.

    Overall summary of first and second vaccine doses administered to the study population as of October 3, 2021.

    Any Vaccine TypeGeneral Population, n = 12,435,914RA, n = 138,304AS, n = 28,509PsA, n = 17,646PsO, n = 182,319IBD, n = 108,792
    Received at least 1 dose10,208,667 (82.1)122,893 (88.9)24,911 (87.4)15,995 (90.6)159,220 (87.3)94,613 (87.0)
          Vaccine product of 1st dosea      
              BNT162b27,384,130 (72.3)89,816 (73.1)17,650 (70.9)11,361 (71.0)113,523 (71.3)67,535 (71.4)
              mRNA-12731,958,127 (19.2)23,225 (18.9)4,564 (18.3)2,746 (17.2)28,655 (18.0)17,604 (18.6)
              ChAdOx1 nCoV-19862,543 (8.4)9,831 (8.0)2,689 (10.8)1,886 (11.8)17,011 (10.7)9,456 (10.0)
    Received 2 doses9,694,968 (78.0)119,198 (86.2)24,082 (84.5)15,556 (88.2)153,521 (84.2)91,187 (83.8)
          Interval between 2 doses, days60 (44–76)70 (54–83)64 (50–78)67 (54–79)65 (50–79)64 (49–78)
    Individuals ≥ 40 days overdue for 2nd doseb237,665 (2.4)2,280 (1.9)412 (1.7)256 (1.6)2,827 (1.8)1,724 (1.9)
    • Values are expressed as n (%) or median (IQR).

    • ↵aIn total, the vaccine type was another product or unknown vaccine product in 3867 individuals.

    • ↵bPotential vaccine dropouts who failed to complete the 2-dose series. AS: ankylosing spondylitis; IBD: inflammatory bowel disease; PsA: psoriatic arthritis; PsO: psoriasis; RA: rheumatoid arthritis.

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The Journal of Rheumatology
Vol. 49, Issue 5
1 May 2022
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COVID-19 Vaccination Uptake Among Individuals With Immune-mediated Inflammatory Diseases in Ontario, Canada, Between December 2020 and October 2021: A Population-based Analysis
Jessica Widdifield, Lihi Eder, Simon Chen, Jeffrey C. Kwong, Carol Hitchon, Diane Lacaille, J. Antonio Aviña-Zubieta, Lawrence W. Svenson, Sasha Bernatsky
The Journal of Rheumatology May 2022, 49 (5) 531-536; DOI: 10.3899/jrheum.211148

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COVID-19 Vaccination Uptake Among Individuals With Immune-mediated Inflammatory Diseases in Ontario, Canada, Between December 2020 and October 2021: A Population-based Analysis
Jessica Widdifield, Lihi Eder, Simon Chen, Jeffrey C. Kwong, Carol Hitchon, Diane Lacaille, J. Antonio Aviña-Zubieta, Lawrence W. Svenson, Sasha Bernatsky
The Journal of Rheumatology May 2022, 49 (5) 531-536; DOI: 10.3899/jrheum.211148
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Keywords

COVID-19
INFLAMMATORY BOWEL DISEASE
PSORIASIS
RHEUMATIC DISEASES
VACCINATION

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