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Research ArticleGout

Which Attributes Are Most and Least Important to Patients When Considering Gout Flare Burden Over Time? A Best-worst Scaling Choice Study

Jeremy Holyer, William J. Taylor, Angelo Gaffo, Graham Hosie, Anne Horne, Borislav Mihov, Isabel Su, Gregory D. Gamble, Nicola Dalbeth and Sarah Stewart
The Journal of Rheumatology February 2022, 49 (2) 213-218; DOI: https://doi.org/10.3899/jrheum.210605
Jeremy Holyer
1J. Holyer, medical student, G. Hosie, NZ Dip. in Policing, A. Horne, MBChB, B. Mihov, BPHty, I. Su, BSc, G.D. Gamble, MSc, N. Dalbeth, MBChB, MD, FRACP, S. Stewart, PhD, Deparment of Medicine, University of Auckland, Auckland, New Zealand;
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William J. Taylor
2W.J. Taylor, MBChB, PhD, FRACP, FAFRM, Department of Medicine, University of Otago, Wellington, New Zealand;
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Angelo Gaffo
3A. Gaffo, MD, MsPH, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
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Graham Hosie
1J. Holyer, medical student, G. Hosie, NZ Dip. in Policing, A. Horne, MBChB, B. Mihov, BPHty, I. Su, BSc, G.D. Gamble, MSc, N. Dalbeth, MBChB, MD, FRACP, S. Stewart, PhD, Deparment of Medicine, University of Auckland, Auckland, New Zealand;
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Anne Horne
1J. Holyer, medical student, G. Hosie, NZ Dip. in Policing, A. Horne, MBChB, B. Mihov, BPHty, I. Su, BSc, G.D. Gamble, MSc, N. Dalbeth, MBChB, MD, FRACP, S. Stewart, PhD, Deparment of Medicine, University of Auckland, Auckland, New Zealand;
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Borislav Mihov
1J. Holyer, medical student, G. Hosie, NZ Dip. in Policing, A. Horne, MBChB, B. Mihov, BPHty, I. Su, BSc, G.D. Gamble, MSc, N. Dalbeth, MBChB, MD, FRACP, S. Stewart, PhD, Deparment of Medicine, University of Auckland, Auckland, New Zealand;
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Isabel Su
1J. Holyer, medical student, G. Hosie, NZ Dip. in Policing, A. Horne, MBChB, B. Mihov, BPHty, I. Su, BSc, G.D. Gamble, MSc, N. Dalbeth, MBChB, MD, FRACP, S. Stewart, PhD, Deparment of Medicine, University of Auckland, Auckland, New Zealand;
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Gregory D. Gamble
1J. Holyer, medical student, G. Hosie, NZ Dip. in Policing, A. Horne, MBChB, B. Mihov, BPHty, I. Su, BSc, G.D. Gamble, MSc, N. Dalbeth, MBChB, MD, FRACP, S. Stewart, PhD, Deparment of Medicine, University of Auckland, Auckland, New Zealand;
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Nicola Dalbeth
1J. Holyer, medical student, G. Hosie, NZ Dip. in Policing, A. Horne, MBChB, B. Mihov, BPHty, I. Su, BSc, G.D. Gamble, MSc, N. Dalbeth, MBChB, MD, FRACP, S. Stewart, PhD, Deparment of Medicine, University of Auckland, Auckland, New Zealand;
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Sarah Stewart
1J. Holyer, medical student, G. Hosie, NZ Dip. in Policing, A. Horne, MBChB, B. Mihov, BPHty, I. Su, BSc, G.D. Gamble, MSc, N. Dalbeth, MBChB, MD, FRACP, S. Stewart, PhD, Deparment of Medicine, University of Auckland, Auckland, New Zealand;
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  • For correspondence: sarah.stewart@auckland.ac.nz
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Abstract

Objective Several factors contribute to the patient experience of gout flares, including pain intensity, duration, frequency, and disability. It is unknown which of these factors are most important to patients when considering flare burden over time, including those related to the cumulative experience of all flares, or the experience of a single worst flare. This study aimed to determine which flare attributes are the most and least important to the patient experience of flare burden over time.

Methods Participants with gout completed an anonymous online survey. Questions were aimed at identifying which attributes of gout flares, representing both individual and cumulative flare burden, were the most and least important over a hypothetical 6-month period. A best-worst scaling method was used to determine the importance hierarchy of the included attributes.

Results Fifty participants were included. Difficulty doing usual activities during the worst flare and pain of the worst flare were ranked as the most important, whereas average pain of all flares was considered the least important. Overall, attributes related to the single worst gout flare were considered more important than attributes related to the cumulative impact of all flares.

Conclusion When thinking about the burden of gout flares over time, patients rank activity limitation and pain experienced during their worst gout flare as the most important contributing factors, whereas factors related to the cumulative impact of all flares over time are relatively less important.

Key Indexing Terms:
  • activities of daily living
  • gout
  • outcome assessment
  • pain
  • Accepted for publication October 13, 2021.
  • © 2022 by the Journal of Rheumatology
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1 Feb 2022
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Which Attributes Are Most and Least Important to Patients When Considering Gout Flare Burden Over Time? A Best-worst Scaling Choice Study
Jeremy Holyer, William J. Taylor, Angelo Gaffo, Graham Hosie, Anne Horne, Borislav Mihov, Isabel Su, Gregory D. Gamble, Nicola Dalbeth, Sarah Stewart
The Journal of Rheumatology Feb 2022, 49 (2) 213-218; DOI: 10.3899/jrheum.210605

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Which Attributes Are Most and Least Important to Patients When Considering Gout Flare Burden Over Time? A Best-worst Scaling Choice Study
Jeremy Holyer, William J. Taylor, Angelo Gaffo, Graham Hosie, Anne Horne, Borislav Mihov, Isabel Su, Gregory D. Gamble, Nicola Dalbeth, Sarah Stewart
The Journal of Rheumatology Feb 2022, 49 (2) 213-218; DOI: 10.3899/jrheum.210605
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Keywords

ACTIVITIES OF DAILY LIVING
GOUT
OUTCOME ASSESSMENT
PAIN

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Keywords

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