Research ArticleSystemic Lupus Erythematosus
Open Access
Relationship Between Genetic Risk and Age of Diagnosis in Systemic Lupus Erythematosus
Daniela Dominguez, Sylvia Kamphuis, Joseph Beyene, Joan Wither, John B. Harley, Irene Blanco, Catarina Vila-Inda, Hermine Brunner, Marissa Klein-Gitleman, Deborah McCurdy, Dawn M. Wahezi, Thomas Lehman, Marija Jelusic, Christine A. Peschken, Janet E. Pope, Dafna D. Gladman, John G. Hanly, Ann E. Clarke, Sasha Bernatsky, Christian Pineau, C. Douglas Smith, Susan Barr, Gilles Boire, Eric Rich and Earl D. Silverman for the Canadian Network for Improved Outcomes in SLE (CaNIOS) and APPLE Investigators
The Journal of Rheumatology June 2021, 48 (6) 852-858; DOI: https://doi.org/10.3899/jrheum.200002
Daniela Dominguez
1D. Dominguez, MSc, Division of Rheumatology, Hospital for Sick Children, Hospital for Sick Children, Research Institute, University of Toronto, Toronto, Ontario, Canada;
Sylvia Kamphuis
2S. Kamphuis, MD, PhD, Division of Rheumatology Department of Pediatrics, Sophia Children’s Hospital, Erasmus Medical Center, Rotterdam, the Netherlands;
Joseph Beyene
3J. Beyene, PhD, Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton;
Joan Wither
4J. Wither, MD, PhD, Division of Genetics and Development, Krembil Research Institute, Arthritis Centre of Excellence, Division of Rheumatology, Toronto Western Hospital, University Health Network, Departments of Medicine and Immunology, University of Toronto, Toronto, Ontario, Canada;
John B. Harley
5J.B. Harley, MD, PhD, Center for Autoimmune Genomics and Etiology, Cincinnati Children’s Hospital Medical Center, and Department of Pediatrics, University of Cincinnati, and US Department of Veterans Affairs Medical Center, Cincinnati, Ohio;
Irene Blanco
6I. Blanco, MD, C. Vila-Inda, MD, Albert Einstein College of Medicine, Division of Rheumatology, Bronx, New York;
Catarina Vila-Inda
6I. Blanco, MD, C. Vila-Inda, MD, Albert Einstein College of Medicine, Division of Rheumatology, Bronx, New York;
Hermine Brunner
7H. Brunner, MD, MSc, Division of Rheumatology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio;
Marissa Klein-Gitleman
8M. Klein-Gitleman, MD, Ann & Robert H. Lurie Children’s Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois;
Deborah McCurdy
9D. McCurdy, MD, Division of Pediaitric Rheumatology, University of California Los Angeles, Los Angeles, California;
Dawn M. Wahezi
10D.M. Wahezi, MD, Children’s Hospital at Montefiore, Division of Pediatric Rheumatology, Albert Einstein College of Medicine, the Bronx, New York;
Thomas Lehman
11T. Lehman, MD, Division of Pediatric Rheumatology, Hospital for Special Surgery, New York, New York, USA;
Marija Jelusic
12M. Jelusic, MD, Department of Pediatric Rheumatology, University of Zagreb School of Medicine, Zagreb, Croatia;
Christine A. Peschken
13C.A. Peschken, MD, MSc, Departments of Medicine and Community Health Sciences, University of Manitoba, Winnipeg, Manitoba;
Janet E. Pope
14J.E. Pope, MD, MPH, Professor of Medicine, Department of Medicine, University of Western Ontario, London, Ontario;
Dafna D. Gladman
15D.D. Gladman, MD, Department of Medicine, University of Toronto, Toronto, Ontario;
John G. Hanly
16J.G. Hanly, MD, Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Center and Dalhousie University, Halifax, Nova Scotia;
Ann E. Clarke
17A.E. Clarke, MD, Cumming School of Medicine, University of Calgary, Calgary, Alberta;
Sasha Bernatsky
18S. Bernatsky, MD, PhD, Department of Medicine, McGill University, Montreal, Quebec;
Christian Pineau
19C. Pineau, MD, Department of Medicine, McGill University Hospital, Montreal, Quebec;
C. Douglas Smith
20C.D. Smith, MD, Department of Medicine, Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario;
Susan Barr
21S. Barr, MD, Division of Rheumatology, Department of Medicine, University of Calgary, Calgary, Alberta;
Gilles Boire
22G. Boire, MD, Division of Rheumatology, Department of Medicine, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec,
Eric Rich
23E. Rich, MD, Division of Rheumatology, Centre Hospitalier de l’Université de Montreal, Department of Medicine, University of Montreal School of Medicine, Montreal, Quebec;
Earl D. Silverman
24E.D. Silverman, MD, FRCPC, Professor Emeritus of Pediatrics, Division of Rheumatology, Department of Pediatrics, SickKids Hospital, SickKids Hospital Research Institute, University of Toronto, Toronto, Ontario, Canada.
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In this issue
The Journal of Rheumatology
Vol. 48, Issue 6
1 Jun 2021
Relationship Between Genetic Risk and Age of Diagnosis in Systemic Lupus Erythematosus
Daniela Dominguez, Sylvia Kamphuis, Joseph Beyene, Joan Wither, John B. Harley, Irene Blanco, Catarina Vila-Inda, Hermine Brunner, Marissa Klein-Gitleman, Deborah McCurdy, Dawn M. Wahezi, Thomas Lehman, Marija Jelusic, Christine A. Peschken, Janet E. Pope, Dafna D. Gladman, John G. Hanly, Ann E. Clarke, Sasha Bernatsky, Christian Pineau, C. Douglas Smith, Susan Barr, Gilles Boire, Eric Rich, Earl D. Silverman
The Journal of Rheumatology Jun 2021, 48 (6) 852-858; DOI: 10.3899/jrheum.200002
Relationship Between Genetic Risk and Age of Diagnosis in Systemic Lupus Erythematosus
Daniela Dominguez, Sylvia Kamphuis, Joseph Beyene, Joan Wither, John B. Harley, Irene Blanco, Catarina Vila-Inda, Hermine Brunner, Marissa Klein-Gitleman, Deborah McCurdy, Dawn M. Wahezi, Thomas Lehman, Marija Jelusic, Christine A. Peschken, Janet E. Pope, Dafna D. Gladman, John G. Hanly, Ann E. Clarke, Sasha Bernatsky, Christian Pineau, C. Douglas Smith, Susan Barr, Gilles Boire, Eric Rich, Earl D. Silverman
The Journal of Rheumatology Jun 2021, 48 (6) 852-858; DOI: 10.3899/jrheum.200002