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Research ArticleRheumatoid Arthritis

Effect on Costs and Quality-adjusted Life-years of Treat-to-target Treatment Strategies Initiating Methotrexate, or Tocilizumab, or Their Combination in Early Rheumatoid Arthritis

Maxime M.A. Verhoeven, Janneke Tekstra, Jacob M. van Laar, Attila Pethö-Schramm, Michelle E.A. Borm, Johannes W.J. Bijlsma, Johannes W.G. Jacobs, Floris P.J.G. Lafeber and Paco M.J. Welsing
The Journal of Rheumatology April 2021, 48 (4) 495-503; DOI: https://doi.org/10.3899/jrheum.200067
Maxime M.A. Verhoeven
1M.M. Verhoeven, PhD student, J. Tekstra, MD, PhD, J.M. van Laar, MD, PhD, J.W. Bijlsma, MD, PhD, J.W. Jacobs, MD, PhD, F.P. Lafeber, PhD, P.M. Welsing, PhD, Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, the Netherlands;
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  • ORCID record for Maxime M.A. Verhoeven
  • For correspondence: m.m.a.verhoeven-15{at}umcutrecht.nl
Janneke Tekstra
1M.M. Verhoeven, PhD student, J. Tekstra, MD, PhD, J.M. van Laar, MD, PhD, J.W. Bijlsma, MD, PhD, J.W. Jacobs, MD, PhD, F.P. Lafeber, PhD, P.M. Welsing, PhD, Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, the Netherlands;
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Jacob M. van Laar
1M.M. Verhoeven, PhD student, J. Tekstra, MD, PhD, J.M. van Laar, MD, PhD, J.W. Bijlsma, MD, PhD, J.W. Jacobs, MD, PhD, F.P. Lafeber, PhD, P.M. Welsing, PhD, Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, the Netherlands;
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Attila Pethö-Schramm
2A. Pethö-Schramm, MD, PhD, F. Hoffmann-La Roche, Basel, Switzerland;
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Michelle E.A. Borm
3M.E. Borm, PhD, Roche Nederland BV, Woerden, the Netherlands.
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Johannes W.J. Bijlsma
1M.M. Verhoeven, PhD student, J. Tekstra, MD, PhD, J.M. van Laar, MD, PhD, J.W. Bijlsma, MD, PhD, J.W. Jacobs, MD, PhD, F.P. Lafeber, PhD, P.M. Welsing, PhD, Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, the Netherlands;
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Johannes W.G. Jacobs
1M.M. Verhoeven, PhD student, J. Tekstra, MD, PhD, J.M. van Laar, MD, PhD, J.W. Bijlsma, MD, PhD, J.W. Jacobs, MD, PhD, F.P. Lafeber, PhD, P.M. Welsing, PhD, Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, the Netherlands;
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  • ORCID record for Johannes W.G. Jacobs
Floris P.J.G. Lafeber
1M.M. Verhoeven, PhD student, J. Tekstra, MD, PhD, J.M. van Laar, MD, PhD, J.W. Bijlsma, MD, PhD, J.W. Jacobs, MD, PhD, F.P. Lafeber, PhD, P.M. Welsing, PhD, Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, the Netherlands;
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Paco M.J. Welsing
1M.M. Verhoeven, PhD student, J. Tekstra, MD, PhD, J.M. van Laar, MD, PhD, J.W. Bijlsma, MD, PhD, J.W. Jacobs, MD, PhD, F.P. Lafeber, PhD, P.M. Welsing, PhD, Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, the Netherlands;
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  • Article
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Article Information

vol. 48 no. 4 495-503
DOI 
https://doi.org/10.3899/jrheum.200067
PubMed 
32739893

Published By 
The Journal of Rheumatology
Print ISSN 
0315-162X
Online ISSN 
1499-2752
History 
  • Accepted for publication July 15, 2020
  • Published online April 1, 2021.

Article Versions

  • Latest version (August 1, 2020 - 04:00).
  • Latest version (November 1, 2020 - 04:00).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2021 by the Journal of Rheumatology

Author Information

  1. Maxime M.A. Verhoeven1⇑,
  2. Janneke Tekstra1,
  3. Jacob M. van Laar1,
  4. Attila Pethö-Schramm2,
  5. Michelle E.A. Borm3,
  6. Johannes W.J. Bijlsma1,
  7. Johannes W.G. Jacobs1,
  8. Floris P.J.G. Lafeber1 and
  9. Paco M.J. Welsing1
  1. 1M.M. Verhoeven, PhD student, J. Tekstra, MD, PhD, J.M. van Laar, MD, PhD, J.W. Bijlsma, MD, PhD, J.W. Jacobs, MD, PhD, F.P. Lafeber, PhD, P.M. Welsing, PhD, Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, the Netherlands;
  2. 2A. Pethö-Schramm, MD, PhD, F. Hoffmann-La Roche, Basel, Switzerland;
  3. 3M.E. Borm, PhD, Roche Nederland BV, Woerden, the Netherlands.
  1. Address correspondence to M.M. Verhoeven, Department of Rheumatology & Clinical Immunology G02.228, Heidelberglaan 100, 3584 CX Utrecht, the Netherlands. Email: m.m.a.verhoeven-15{at}umcutrecht.nl.

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The Journal of Rheumatology
Vol. 48, Issue 4
1 Apr 2021
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Effect on Costs and Quality-adjusted Life-years of Treat-to-target Treatment Strategies Initiating Methotrexate, or Tocilizumab, or Their Combination in Early Rheumatoid Arthritis
Maxime M.A. Verhoeven, Janneke Tekstra, Jacob M. van Laar, Attila Pethö-Schramm, Michelle E.A. Borm, Johannes W.J. Bijlsma, Johannes W.G. Jacobs, Floris P.J.G. Lafeber, Paco M.J. Welsing
The Journal of Rheumatology Apr 2021, 48 (4) 495-503; DOI: 10.3899/jrheum.200067

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Effect on Costs and Quality-adjusted Life-years of Treat-to-target Treatment Strategies Initiating Methotrexate, or Tocilizumab, or Their Combination in Early Rheumatoid Arthritis
Maxime M.A. Verhoeven, Janneke Tekstra, Jacob M. van Laar, Attila Pethö-Schramm, Michelle E.A. Borm, Johannes W.J. Bijlsma, Johannes W.G. Jacobs, Floris P.J.G. Lafeber, Paco M.J. Welsing
The Journal of Rheumatology Apr 2021, 48 (4) 495-503; DOI: 10.3899/jrheum.200067
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Keywords

BIOLOGICAL THERAPIES
DISEASE-MODIFYING ANTIRHEUMATIC DRUGS
EPIDEMIOLOGY
health economics
RHEUMATOID ARTHRITIS
QUALITY OF LIFE

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Keywords

  • biological therapies
  • DISEASE-MODIFYING ANTIRHEUMATIC DRUGS
  • epidemiology
  • health economics
  • rheumatoid arthritis
  • quality of life

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