Porphyria Cutanea Tarda Masquerading as Systemic Sclerosis: Two Cases Demonstrating an Important Clinical Observation

Elizabeth Tkachenko; Joseph C. Pierson; Ruth Ann Vleugels

doi:10.3899/jrheum.190982

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Porphyria Cutanea Tarda Masquerading as Systemic Sclerosis: Two Cases Demonstrating an Important Clinical Observation

Elizabeth Tkachenko, Joseph C. Pierson and Ruth Ann Vleugels

The Journal of Rheumatology January 2021, 48 (1) 145-146; DOI: https://doi.org/10.3899/jrheum.190982

Elizabeth Tkachenko

Department of Internal Medicine, Brigham & Women’s Hospital, Boston, Massachusetts

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ORCID record for Elizabeth Tkachenko

Joseph C. Pierson

Department of Dermatology, University of Vermont Medical Center, Burlington, Vermont

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Ruth Ann Vleugels

Department of Dermatology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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For correspondence: rvleugels@bwh.harvard.edu

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Porphyria cutanea tarda (PCT) is a heme biosynthesis disorder characterized by photosensitive bullae and skin fragility¹. Sclerodermoid changes and dystrophic calcification are uncommon, occurring in 18% and 8% of patients, respectively¹. Scarring alopecia in PCT, or alopecia porphyrinica, is rarely described, with 5 reports to date^2,3,4,5,6,7.

A 75-year-old man with longstanding facial and …

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The Journal of Rheumatology

Vol. 48, Issue 1

1 Jan 2021

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Porphyria Cutanea Tarda Masquerading as Systemic Sclerosis: Two Cases Demonstrating an Important Clinical Observation