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Research ArticleSpondyloarthritis

Entheseal Changes in Response to Age, Body Mass Index, and Physical Activity: An Ultrasound Study in Healthy People

Sibel Bakirci, Dilek Solmaz, Wilson Stephenson, Lihi Eder, Johannes Roth and Sibel Zehra Aydin
The Journal of Rheumatology July 2020, 47 (7) 968-972; DOI: https://doi.org/10.3899/jrheum.190540
Sibel Bakirci
From the Faculty of Medicine, Division of Rheumatology, and the Division of Internal Medicine, University of Ottawa, Ottawa; Women’s College Research Institute, Women’s College Hospital; Department of Medicine, University of Toronto, Toronto; Division of Pediatric Dermatology and Rheumatology, Children’s Hospital of Eastern Ontario; The Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
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  • ORCID record for Sibel Bakirci
Dilek Solmaz
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Wilson Stephenson
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Lihi Eder
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Johannes Roth
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Sibel Zehra Aydin
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  • For correspondence: saydin@toh.ca
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    Figure 1.

    The effect of age on enthesitis scores as revealed by ultrasound.

Tables

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    Table 1.

    Defining elementary lesions at entheses sites according to age groups.

    Entheses SitesElementary LesionsAge ≤ 50 Yrs, n = 51Age > 50 Yrs, n = 29Total, n = 80, n (%)
    Quadriceps tendon
    Hypoechogenicity (H)01919 (23.7)
    Thickening (T)41014 (17.5)
    H and T088 (10.0)
    Power Doppler000
    Enthesophyte122032 (40.0)
    Calcification033 (3.75)
    Erosion011 (1.25)
    Proximal patellar tendon
    Hypoechogenicity (H)011 (1.25)
    Thickening (T)342256 (70.0)
    H and T011 (1.25)
    Power Doppler000
    Enthesophyte347 (8.75)
    Calcification112 (2.50)
    Erosion000
    Distal patellar tendon
    Hypoechogenicity (H)9514 (17.5)
    Thickening (T)241337 (46.2)
    H and T549 (11.25)
    Power Doppler112 (2.50)
    Enthesophyte8917 (21.5)
    Calcification729 (11.2)
    Erosion033 (3.75)
    Achilles tendon
    Hypoechogenicity (H)11112 (15.0)
    Thickening (T)066 (7.50)
    H and T033 (3.75)
    Power Doppler044 (5.0)
    Enthesophyte362763 (78.7)
    Calcification224 (5.0)
    Erosion000
    Plantar fascia
    Hypoechogenicity (H)022 (2.50)
    Thickening (T)61218 (22.5)
    H and T011 (1.25)
    Power Doppler000
    Enthesophyte066 (7.50)
    Calcification000
    Erosion112 (2.50)
    Triceps tendon
    Hypoechogenicity (H)358 (10.0)
    Thickening (T)022 (2.50)
    H and T000
    Power Doppler123 (3.75)
    Enthesophyte101222 (27.5)
    Calcification123 (3.75)
    Erosion000
    • View popup
    Table 2.

    Multivariate regression results of the factors affecting ultrasound scores.

    Inflammation ScoreDamage ScoreTotal Score
    B (95% CI)pB (95% CI)pB (95% CI)p
    Variables
    Intercept−13.2 (−19.3 to −7.1)< 0.001−12.0 (−17.7 to −6.4)< 0.001−25.3 (−35.3 to −15.2)< 0.001
    Age0.17 (0.10–0.23)< 0.0010.18 (0.13–0.24)< 0.0010.35 (0.25–0.46)< 0.001
    Sex (men vs women)2.73 (0.78–4.68)0.0072.3 (0.49–4.1)0.0145.05 (1.82–8.28)0.003
    Smoking (ever vs never)−0.046 (−2.0 to 1.97)0.963−0.10 (−1.9 to 1.7)0.916−0.14 (−3.46 to 3.16)0.930
    BMI0.35 (0.13–0.57)0.0020.26 (0.05–0.46)0.0140.61 (0.24–0.97)0.001
    Physical activity (high vs low and moderate)1.89 (−0.022 to 3.80)0.0532.5 (0.73–4.3)0.0064.41 (1.25–7.58)0.007
    Observations: 76Observations: 76Observations: 76
    R2/adjusted R2: 0.500/0.465R2/adjusted R2: 0.547/0.515R2/adjusted R2: 0.599/0.571
    • Significant differences are in bold face. BMI: body mass index.

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1 Jul 2020
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Entheseal Changes in Response to Age, Body Mass Index, and Physical Activity: An Ultrasound Study in Healthy People
Sibel Bakirci, Dilek Solmaz, Wilson Stephenson, Lihi Eder, Johannes Roth, Sibel Zehra Aydin
The Journal of Rheumatology Jul 2020, 47 (7) 968-972; DOI: 10.3899/jrheum.190540

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Entheseal Changes in Response to Age, Body Mass Index, and Physical Activity: An Ultrasound Study in Healthy People
Sibel Bakirci, Dilek Solmaz, Wilson Stephenson, Lihi Eder, Johannes Roth, Sibel Zehra Aydin
The Journal of Rheumatology Jul 2020, 47 (7) 968-972; DOI: 10.3899/jrheum.190540
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Keywords

ENTHESIS
ULTRASOUND
HEALTHY SUBJECTS

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