Concurrent septic arthritis and osteomyelitis present a challenging situation in a medically complex patient with joint and bone pain. We report on an immunosuppressed patient who developed urosepsis with bacteremia followed sequentially by septic arthritis and osteomyelitis, emphasizing the potential musculoskeletal sites of disseminated bacterial infection in the susceptible host.
A 46-year-old woman presented with unilateral knee pain of 3 months’ duration. Her history was notable for follicular lymphoma, treated with rituximab (RTX) and cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy. Relapse warranted RTX and ifosfamide, carboplatin, and etoposide chemotherapy and allogeneic …