To the Editor:
We value Dr. Caricchio’s and Dr. Criner’s appreciation of our commentary on the role of rheumatologists in the coronavirus disease 2019 (COVID-19) pandemic1. We applaud Temple University for collaborating in the care of hospitalized patients with COVID-19, many of whom are experiencing a cytokine storm syndrome (CSS)2. COVID-19 infection results in up to 20% of individuals requiring hospitalization for pneumonia, which can progress to acute respiratory distress syndrome, shock, and multiorgan dysfunction syndrome3. Many of the clinical and laboratory features of hospitalized patients with COVID-19 are reminiscent of a CSS1,4,5. Because CSS is frequently fatal, recognition of the CSS and early initiation of treatment directed specifically at the CSS is critical for reducing mortality …
Address correspondence to Dr. R.Q. Cron, Children’s of Alabama, Division of Rheumatology, 1600 7th Ave. S., CPPN, Suite G10, Birmingham, AL 35233-1711, USA. Email: rcron{at}peds.uab.edu.