Identifying Persons with Axial Spondyloarthritis At Risk of Poor Work Outcome: Results from the British Society for Rheumatology Biologics Register

Article Figures & Data

Table 1.

Baseline characteristics of the BSRBR-AS population.

Characteristics	Working, n = 1188	Not Working, n = 733
Age, yrs ^**	43.7 (34.6–52.3)	62.2 (48.1–68.3)
Age at rheumatology referral, yrs^**	33 (26–42)	41 (29–52)
Sex, male^*	767 (65)	529 (72)
Classification criteria^**
Modified New York criteria	635 (53)	237 (32)
ASAS imaging	475 (40)	383 (52)
ASAS clinical	78 (7)	113 (15)
HLA-B27 status^**
Positive	684 (83)	337 (75)
Negative	145 (17)	115 (25)
Job type
Sedentary	715 (55)	–
Labor-intensive	592 (45)	–
Absenteeism, %	0 (0–0)	–
Presenteeism, %	30 (10–50)	–
Overall work impairment, %	30 (10–53)	–
Activity impairment (%)^**	30 (10–60)	60 (30–80)
	Logistic Regression^†
Likelihood of working^**	OR	95% CI
BASDAI (scored: 0 best–10 worst)	0.74	0.70–0.79
BASFI (scored: 0 best–10 worst)	0.70	0.66–0.73
BASMI (scored: 0 best–10 worst)	0.69	0.64–0.75
ASQoL (scored: 0 best–18 poorest)	0.84	0.81–0.86

Values are n (%) or median (IQR) unless otherwise indicated.
↵* Statistically significant difference between work and not working of p < 0.05.
↵** Statistically significant difference between work and not working of p < 0.01.
↵† Adjusted for age, sex, and deprivation. BSRBR-AS: British Society for Rheumatology Biologics Register in Ankylosing Spondylitis; ASAS: Assessment of Spondyloarthritis international Society; BASDAI: Bath Ankylosing Spondylitis Disease Activity Index; BASFI: Bath AS Functional Index; BASMI: Bath AS Metrology Index; ASQoL: Ankylosing Spondylitis Quality of Life questionnaire; IQR: interquartile range.