Article Figures & Data
Tables
Characteristics Mild PsA, n = 5611 Moderate PsA, n = 3479 Severe PsA, n = 1487 p Age, yrs, mean (SD) 57.0 (14.5) 57.9 (13.6) 53.7 (12.8) < 0.001 Women 3278 (58.4) 2080 (59.8) 810 (54.5) 0.002 Men 2333 (41.6) 1399 (40.2) 677 (45.5) Socioeconomic status < 0.001 Lowest 308 (5.5) 154 (4.4) 68 (4.6) Below average 1329 (23.7) 900 (25.9) 277 (18.6) Average 1440 (25.7) 964 (27.7) 402 (27.0) Above average 1322 (23.6) 816 (23.5) 398 (26.8) Highest 1212 (21.6) 645 (18.5) 342 (23.0) Time since diagnosis, yrs, mean (SD) 8.9 (7.0) 10.1 (6.2) 10.5 (6.0) < 0.001 Smoking 945 (16.8) 592 (17.0) 233 (15.7) 0.483 Alcohol abuse 415 (7.4) 200 (5.8) 89 (6.0) 0.005 Hypertension 488 (8.7) 310 (8.9) 112 (7.5) 0.266 Diabetes 631 (11.3) 426 (12.2) 167 (11.2) 0.318 CCI score, mean (SD) 0.3 (0.8) 0.3 (0.9) 0.3 (0.8) < 0.001 Crohn disease 38 (0.7) 26 (0.8) 11 (0.7) 0.917 Ulcerative colitis 42 (0.8) 35 (1.0) 16 (1.1) 0.301 Peripheral vascular disease 47 (0.8) 35 (1.0) 11 (0.7) 0.581 Cerebrovascular disease 124 (2.2) 93 (2.7) 23 (1.6) 0.046 Ischemic heart disease 203 (3.6) 151 (4.1) 64 (4.2) 0.446 Previous myocardial infarction 56 (1.0) 47 (1.4) 24 (1.6) 0.093 Cardiac dysrythmia 208 (3.7) 138 (4.0) 39 (2.6) 0.063 Antidepressant drug use 709 (12.6) 444 (12.8) 200 (13.5) 0.704 SSRI 519 (9.3) 308 (8.9) 134 (9.1) 0.810 TCA 222 (4.0) 158 (4.5) 76 (5.1) 0.107 SNRI 385 (6.9) 278 (8.0) 91 (6.1) 0.033 Other 3 (0.1) 0 (0.0) < 3* 0.364 Antipsychotics 218 (3.9) 119 (3.4) 48 (3.2) 0.340 Anxiolytic drug use 219 (3.9) 137 (3.9) 50 (3.4) 0.586 Psychologist consultation 136 (2.4) 51 (1.5) 47 (3.2) < 0.001 Psychiatrist consultation 86 (1.5) 44 (1.3) 26 (1.8) 0.337 Any psoriasis 3779 (67.4) 2303 (66.2) 1075 (72.3) < 0.001 Dermatologist-diagnosed psoriasis 1552 (27.7) 687 (19.8) 531 (35.7) < 0.001 Mild psoriasis 656 (11.7) 355 (10.2) 277 (18.6) Moderate psoriasis 578 (10.3) 236 (6.8) 140 (9.4) Severe psoriasis 318 (5.7) 96 (2.8) 114 (7.7) Data are n (%) unless otherwise specified.
↵* Data shown as < 3 because of data security requirements. PsA: psoriatic arthritis; CCI: Charlson Comorbidity Index; SSRI: selective serotonin reuptake inhibitors; TCA: tricyclic antidepressants; SNRI: serotonin norepinephrine reuptake inhibitor.
Variables Psoriasis p Mild, n = 11,341 Moderate, n = 6690 Severe, n = 1431 Any diagnosis of PsA 1845 (16.3) 1359 (20.3) 685 (47.9) < 0.001 Rheumatologist-diagnosed PsA 1288 (11.4) 954 (14.3) 528 (36.9) < 0.001 Mild PsA 656 (5.8) 578 (8.6) 318 (22.2) Moderate PsA 355 (3.1) 236 (3.5) 96 (6.7) Severe PsA 277 (2.4) 140 (2.1) 114 (8.0) Data are n (%). PsA: psoriatic arthritis.