Article Figures & Data
Figures
- Figure 1.
Correlations between multiple aPL and thrombosis (A), venous thrombosis (B), arterial thrombosis (C), and obstetrical complications (D). aPL: antiphospholipid antibodies; aPT/PS: antiprothrombin/antiphosphatidylserine antibodies; aCL: anticardiolipin antibodies; aβ2GPI: anti-β2-glycoprotein I; LA: lupus anticoagulants.
Tables
- Table 1.
The predictive power of combination of various aPL in the diagnosis of APS. Except for likelihood ratios (LR), data are percentages.
Sensitivity Specificity PPV NPV LR+ LR– aPT/PS IgG or IgM or LAC 79.70 79.50 85.30 72.30 3.89 0.26 aPT/PS IgG or IgM or aCL IgG or IgM 78.80 77.00 83.70 70.90 3.43 0.27 aPT/PS IgG or IgM or anti-β2-GPI IgG or IgM 73.40 79.50 84.30 66.70 3.58 0.33 LAC or aCL IgG or IgM or anti-β2-GPI IgG or IgM 84.20 84.50 89.00 78.20 5.42 0.19 LAC or aCL IgG or IgM or anti-β2-GPI IgG or IgM or aPT/PS IgG or IgM 87.10 71.40 82.00 78.80 3.05 0.18 aPT/PS IgG or IgM and LAC 52.70 99.40 99.20 58.40 84.84 0.48 aPT/PS IgG or IgM and aCL IgG or IgM 46.90 98.10 97.40 55.20 25.16 0.54 aPT/PS IgG or IgM and anti-β2-GPI IgG or IgM 29.90 98.80 97.30 48.50 24.05 0.71 aCL IgG or IgM and LAC 46.90 99.40 99.10 55.60 75.49 0.53 anti-β2-GPI IgG or IgM and LAC 30.70 98.80 97.40 48.80 24.72 0.70 LAC and aCL IgG or IgM and aPT/PS IgG or IgM 38.60 100.00 100.00 52.10 NA 0.61 LAC and aCL IgG or IgM and anti-β2-GPI IgG or IgM 29.50 99.40 98.60 48.50 47.43 0.71 LAC and aCL IgG or IgM and anti-β2-GPI IgG or IgM and aPT/PS IgG or IgM 23.20 100.00 100.00 46.50 NA 0.77 aPL: antiphospholipid antibodies; APS: antiphospholipid syndrome; PPV: positive predictive value; NPV: negative predictive value; NA: not applicable; aPT/PS: antiphosphatidylserine/prothrombin antibodies; aCL: anticardiolipin antibodies; anti-β2-GPI: anti-β2-glycoprotein I; LAC: lupus anticoagulants.
