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Research ArticleOMERACT 2016 – International Consensus Conference on Outcome Measures in Rheumatology, Whistler, British Columbia, Canada, May 2016

The OMERACT Ultrasound Group: A Report from the OMERACT 2016 Meeting and Perspectives

Lene Terslev, Annamaria Iagnocco, George A.W. Bruyn, Esperanza Naredo, Jelena Vojinovic, Paz Collado, Nemanja Damjanov, Andrew Filer, Georgios Filippou, Stephanie Finzel, Frederique Gandjbakhch, Kei Ikeda, Helen I. Keen, Marion C. Kortekaas, Silvia Magni-Manzoni, Sarah Ohrndorf, Carlos Pineda, Viviana Ravagnani, Bethan Richards, Ilfita Sahbudin, Wolfgang A. Schmidt, Heidi J. Siddle, Maria S. Stoenoiu, Marcin Szkudlarek, Nikolay Tzaribachev, Maria-Antonietta D’Agostino and on behalf of the OMERACT Ultrasound Group
The Journal of Rheumatology November 2017, 44 (11) 1740-1743; DOI: https://doi.org/10.3899/jrheum.161240
Lene Terslev
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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  • For correspondence: terslev@dadlnet.dk
Annamaria Iagnocco
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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George A.W. Bruyn
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Esperanza Naredo
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Jelena Vojinovic
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Paz Collado
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Nemanja Damjanov
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Andrew Filer
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Georgios Filippou
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Stephanie Finzel
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Frederique Gandjbakhch
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Kei Ikeda
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Helen I. Keen
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Marion C. Kortekaas
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Silvia Magni-Manzoni
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Sarah Ohrndorf
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Carlos Pineda
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Viviana Ravagnani
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Bethan Richards
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Ilfita Sahbudin
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Wolfgang A. Schmidt
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Heidi J. Siddle
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Maria S. Stoenoiu
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Marcin Szkudlarek
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Nikolay Tzaribachev
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Maria-Antonietta D’Agostino
From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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From the Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen; Department of Rheumatology, Zealand’s University Hospital, Køge, Denmark; Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino, Turin; Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Siena; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital, Mantua, Italy; Department of Rheumatology, MC Groep, Lelystad; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz; Autónoma University; Hospital Universitario Severo Ochoa, Madrid, Spain; Clinic Center, Faculty of Medicine, University of Niš, Niš; Institute of Rheumatology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Rheumatology Research Group, The University of Birmingham, Birmingham; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg; Charite University Hospital, Humboldt University; Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt; INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180 Saint-Quentin en Yvelines, Paris, France; Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan; Department of Rheumatology, Royal Perth Hospital, Perth, Australia; Instituto Nacional de Rehabilitacion, Mexico City, Mexico; Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital, Camperdown, Australia; Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Brussels, Belgium.
L. Terslev, MD, PhD, Center for Rheumatology and Spine Diseases, Rigshospitalet; A. Iagnocco, MD, Dipartimento Scienze Cliniche e Biologiche — Reumatologia, Università degli Studi di Torino; G.A. Bruyn, MD, PhD, Department of Rheumatology, MC Groep; E. Naredo, MD, Department of Rheumatology, Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, and Autónoma University; J. Vojinovic, MD, PhD, Clinic Center, Faculty of Medicine, University of Niš; P. Collado, MD, Hospital Universitario Severo Ochoa; N. Damjanov, MD, PhD, Institute of Rheumatology, Faculty of Medicine, University of Belgrade; A. Filer, MD, PhD, Rheumatology Research Group, The University of Birmingham; G. Filippou, MD, Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena; S. Finzel, MD, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg; F. Gandjbakhch, MD, APHP, Department of Rheumatology, CHU Pitie-Salpetriere, Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health; K. Ikeda, MD, PhD, Department of Allergy and Clinical Immunology, Chiba University Hospital; H.I. Keen, MD, PhD, Department of Rheumatology, Royal Perth Hospital; M.C. Kortekaas, MD, PhD, Department of Rheumatology, Leiden University Medical Center; S. Magni-Manzoni, MD, Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù; S. Ohrndorf, MD, Charite University Hospital, Humboldt University; C. Pineda, MD, Research Directorate, Instituto Nacional de Rehabilitacion; V. Ravagnani MD, PhD, Internal Medicine Department, Azienda Socio Sanitaria Territoriale di Mantova, C. Poma Hospital; B. Richards, MD, Rheumatology Institute of Rheumatology and Orthopedics, Royal Prince Alfred Hospital; I. Sahbudin, MD, Rheumatology Research Group, The University of Birmingham; W.A. Schmidt, MD, Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch; H.J. Siddle, MSc, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; M.S. Stoenoiu, MD, PhD, Department of Rheumatology, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc; M. Szkudlarek, MD, PhD, Department of Rheumatology, Zealand’s University Hospital at Køge; N. Tzaribachev, MD, Pediatric Rheumatology Research Institute; M.A. D’Agostino, MD, PhD, APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100 Boulogne-Billancourt, and INSERM U1173, Laboratoire d’Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University.
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Abstract

Objective. To provide an update from the Outcome Measures in Rheumatology (OMERACT) Ultrasound Working Group on the progress for defining ultrasound (US) minimal disease activity threshold at joint level in rheumatoid arthritis (RA) and for standardization of US application in juvenile idiopathic arthritis (JIA).

Methods. For minimal disease activity, healthy controls (HC) and patients with early arthritis (EA) who were naive to disease-modifying antirheumatic drugs were recruited from 2 centers. US was performed of the hands and feet, and scored semiquantitatively (0–3) for synovial hypertrophy (SH) and power Doppler (PD). Synovial effusion (SE) was scored a binary variable. For JIA, a Delphi approach and subsequent validation in static images and patient-based exercises were used to developed preliminary definitions for synovitis and a scoring system.

Results. For minimal disease activity, 7% HC had at least 1 joint abnormality versus 30% in the EA group. In HC, the findings of SH and PD were predominantly grade 1 whereas all grades were seen in the EA cohort, but SE was rare. In JIA, synovitis can be diagnosed based on B-mode findings alone because of the presence of physiological vascularization. A semiquantitative scoring system (0–3) for synovitis for both B-mode and Doppler were developed in which the cutoff between Doppler grade 2 and grade 3 was 30%.

Conclusion. The first step has been taken to define the threshold for minimal disease activity in RA by US and to define and develop a scoring system for synovitis in JIA. Further steps are planned for the continuous validation of US in these areas.

Key Indexing Terms:
  • OMERACT
  • RHEUMATOID ARTHRITIS
  • ULTRASONOGRAPHY
  • JUVENILE IDIOPATHIC ARTHRITIS

The recent Outcome Measures in Rheumatology (OMERACT) 2016 meeting held in Whistler, British Columbia, Canada, in May 2016 provided the opportunity for the OMERACT Ultrasound Working Group (WG) to present the new areas in which ultrasound (US) has progressed and the related validation process. Since the initiation of the group in 2004, the main focus over the past 12 years has been on validating US as an outcome measurement instrument, and an update of the group activities was recently published1. Initially, the US WG focused on rheumatoid arthritis (RA), but with the increasing use of US in other rheumatological conditions, the group expanded the validation work to new areas, which has led the US WG to form subgroups with individual focus areas. At the OMERACT meeting in Whistler, Canada, several subgroups presented their progress. The purpose of our report was to provide an update from 2 of the subgroups: the one working on the definition of US minimal disease activity in RA, and the pediatric subgroup, which is validating the use of US in juvenile idiopathic arthritis (JIA). Both subgroups have been working with pathophysiological manifestation (synovitis) in RA and JIA as the core domain according to the OMERACT filter 2.02.

Further development in RA

The US WG group has validated US in RA by defining elementary lesions such as tenosynovitis and synovitis, including its components3,4, and developed and validated a consensus-based scoring system for synovitis and tenosynovitis for clinical trials5,6,7,8,9,10 with a good sensitivity to change11. However, US elementary lesions such as synovial effusion (SE) and synovial hypertrophy (SH; with or without Doppler activity as a measurable sign of inflammatory activity) may be seen in healthy controls (HC)12,13. Therefore a threshold is needed for separating normal findings from pathology, thereby creating a definition for what may be perceived as minimal disease criteria. This will influence the definition of early disease onset, the optimal response to therapy, and the identification of US remission. The subgroup working on defining minimal disease criteria for RA presented data comparing US findings obtained in HC with US findings obtained from an early arthritis (EA) cohort with the aim of identifying which US elementary components are present in the joints of HC, their prevalence, and their preferred location, and how these differ from patients with EA. This comparison represents the first step in identifying the US findings clinically important in EA and to describe at joint level which US lesions should be considered pathological.

In the conducted study, US findings of SH, SE, and power Doppler (PD) in joints of HC and patients with EA were systematically documented, and the distribution and grading of the findings at joint level were compared to reassess the threshold of abnormality in regions of overlap.

The participants were recruited from 2 centers: the healthy subjects from Ambroise Pare Hospital, Boulogne-Billancourt, France, and the patients with EA from City Hospital and Queen Elizabeth Hospital, Birmingham, UK. The healthy subjects were excluded if they had previous or present signs of joint disease13. Patients with EA who were naive to disease-modifying antirheumatic drugs (DMARD) were included if they had ≥ 1 clinically swollen joint due to inflammatory arthritis as judged by a physician and symptom duration ≤ 3 months. DMARD-naive patients with EA were excluded if joint symptoms were solely attributed to osteoarthritis (OA). US was performed on the wrist and metacarpophalangeal 1–5 joints (MCP), proximal interphalangeal 1–5 joints (PIP), and metatarsophalangeal 2–5 joints (MTP), and SH and PD were scored semiquantitatively (0–3) using the consensus-based European League Against Rheumatism-OMERACT scoring system9; SE was scored as a binary variable.

The demographics results of the 2 cohorts are shown in Table 1.

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Table 1.

Demographics for the healthy subjects and patients with early arthritis.

In HC, 7% had at least 1 joint abnormality versus 30% in the EA group. In HC, the abnormalities were seen in the wrist, MCP 1–4, and MTP 2–4, whereas SH and PD could be seen in all types of examined joints in the EA cohort, but SE was rare. In HC, the findings of SH were predominantly grade 1, although grade 2 and grade 3 could also rarely be found. In the EA cohort, all grades were seen, with grade 3 being most frequent in the MCP. For PD, only grade 1 was seen in HC, whereas grades 1–3 were seen in the EA cohort.

The next step is to determine a cutoff level and to study a group of healthy elderly participants, because the grade of synovial hypertrophy-like changes appears to be age-related14.

Validating US in pediatrics

The increasing need for the use of US in pediatric rheumatology led to the formation of the pediatric subgroup. To test validity and to improve the applicability of US in JIA, in 2011–2012 the subgroup investigated the use of US among pediatric rheumatologists15 and performed a systematic literature review16, which highlighted face and content validity of US for detecting synovitis in JIA with higher sensitivity than clinical examination.

Then the subgroup defined and validated the components of healthy pediatric joints in a multistep consensus process involving a panel of international experts on musculoskeletal ultrasound (MSUS) in children.

In the first step, a group of experts joined a Web-based consensus process to develop definitions for the following components of the pediatric joint: hyaline cartilage, secondary ossification center, joint capsule, synovial membrane, and cortical ossified bone. A definition reaching ≥ 80% of agreement on a Likert scale from 1–5 was accepted17.

In the second step, in a face-to-face meeting, a subgroup of these experts produced additional definitions for 2 joint components that were considered relevant in physiological vascularization of a pediatric joint, i.e., fat pad and physis, which were not described in detail in the previous definitions of pediatric joint components18.

In the third step, the applicability of the previous and new definitions was tested in a live exercise involving healthy children. Following standardized image acquisition and machine-setting protocols, 4 joints (i.e., wrist, second MCP, knee, and ankle) were examined in 4 different age groups (toddler and preschool ages 2–4 yrs, young children ages 5–8 yrs, preadolescent ages 9–12 yrs, and teenager ages 13–16 yrs). Using κ statistics, the intraobserver agreement for the applicability of all definitions ranged from 0.44–1, and for the interobserver agreement ranged from 0.33–1, with highest agreement for the wrist and lowest for MCP 2. Thereafter, the 2 new definitions from the second step were agreed on through a Delphi process among a wider group of pediatric MSUS experts (manuscript in preparation).

Further, the group defined age-related findings, i.e., physiological vascularization and ossification grade in healthy children. In a live exercise with healthy children, it was shown that physiological vascularization can be detected with up to 3 solitary PD signals within the normal joint owing to physiological vascularization localized predominantly in the fat pad, the epiphysis, the physis, and the short bone cartilage. Additionally, the group developed an ossification grade definition in children19.

Using the same methodology, the subgroup moved to define and validate the US elementary lesions in JIA and developed preliminary definitions for synovitis as presented in Table 2, in which synovitis can be based on B-mode findings alone, but not solely on the Doppler20. Taking this synovitis definition and the previously investigated physiological vascularization into account, the group developed a semiquantitative scoring system (0–3) for synovitis for both B-mode and Doppler mode through a Delphi process and a face-to-face meeting (manuscript in preparation). The scoring system was tested in a JIA patient-based exercise conducted in 2016. Scoring of synovitis is applicable only if synovial hypertrophy has been detected on B-mode. Doppler scoring differs from the Doppler scoring applied in adults9, in which Doppler grade 2 and grade 3 are related to Doppler activity below or above 50% of the SH, respectively, whereas in children the cutoff between Doppler grade 2 and grade 3 is 30%.

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Table 2.

Preliminary definitions for the sonographic features of synovitis in children.

The next step is to test the reliability of the scoring system and its sensitivity to change.

Current perspectives

At the OMERACT 2016 meeting, new data were presented from the vasculitis subgroup, the RA in the foot and ankle subgroup, the gout subgroup, and the calcium pyrophosphate disease (CPPD) subgroup. The vasculitis and CPPD subgroups had performed systematic literature reviews and identified proposed definitions for elementary lesion in giant cell arteritis and in CPPD. After circulating these in Delphi exercises, agreements for the definitions of elementary lesions in vasculitis and CPPD were obtained.

Considerable progress has been made in the already existing subgroups for OA in the hand and foot, cartilage damage in RA, synovial biopsies, bone erosions and vessel channels, dactylitis, and psoriatic arthritis. The US group has also moved to new areas in rheumatology such as Sjögren syndrome and scleroderma, and initiated validation procedures.

APPENDIX 1

List of study collaborators. OMERACT Ultrasound Group: Philippe Aegerter, Sibel Aydin, Marina Backhaus, Arthur Bachta, Peter Balint, Hilde Berner Hammer, David Bong, Isabelle Chary-Valckenaere, Philip Conaghan, Eugenio De Miguel, Andrea Delle Sedie, Christian Dejaco, Emilio Filippucci, Jane E. Freeston, Walther Grassi, Marwin Gutierrez, Petra Hanova, Cristina Hernandez, Sandrine Jousse-Joulin, Fredrick Joshua, David Kane, Zunaid Karim, Gurjit Kealey, Juhani Koski, Damien Loeuille, Clara Malattia, Peter Mandl, Michaela Micu, Ingrid Möller, Johannes Roth, Nanno Swen, Ralf Thiele, Violeta Vlad, Richard J. Wakefield, and Daniel Windschall.

Footnotes

  • As part of the supplement series OMERACT 13, this report was reviewed internally and approved by the Guest Editors for integrity, accuracy, and consistency with scientific and ethical standards.

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The Journal of Rheumatology
Vol. 44, Issue 11
1 Nov 2017
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The OMERACT Ultrasound Group: A Report from the OMERACT 2016 Meeting and Perspectives
Lene Terslev, Annamaria Iagnocco, George A.W. Bruyn, Esperanza Naredo, Jelena Vojinovic, Paz Collado, Nemanja Damjanov, Andrew Filer, Georgios Filippou, Stephanie Finzel, Frederique Gandjbakhch, Kei Ikeda, Helen I. Keen, Marion C. Kortekaas, Silvia Magni-Manzoni, Sarah Ohrndorf, Carlos Pineda, Viviana Ravagnani, Bethan Richards, Ilfita Sahbudin, Wolfgang A. Schmidt, Heidi J. Siddle, Maria S. Stoenoiu, Marcin Szkudlarek, Nikolay Tzaribachev, Maria-Antonietta D’Agostino, on behalf of the OMERACT Ultrasound Group
The Journal of Rheumatology Nov 2017, 44 (11) 1740-1743; DOI: 10.3899/jrheum.161240

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The OMERACT Ultrasound Group: A Report from the OMERACT 2016 Meeting and Perspectives
Lene Terslev, Annamaria Iagnocco, George A.W. Bruyn, Esperanza Naredo, Jelena Vojinovic, Paz Collado, Nemanja Damjanov, Andrew Filer, Georgios Filippou, Stephanie Finzel, Frederique Gandjbakhch, Kei Ikeda, Helen I. Keen, Marion C. Kortekaas, Silvia Magni-Manzoni, Sarah Ohrndorf, Carlos Pineda, Viviana Ravagnani, Bethan Richards, Ilfita Sahbudin, Wolfgang A. Schmidt, Heidi J. Siddle, Maria S. Stoenoiu, Marcin Szkudlarek, Nikolay Tzaribachev, Maria-Antonietta D’Agostino, on behalf of the OMERACT Ultrasound Group
The Journal of Rheumatology Nov 2017, 44 (11) 1740-1743; DOI: 10.3899/jrheum.161240
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  • Article
    • Abstract
    • Further development in RA
    • Validating US in pediatrics
    • Current perspectives
    • APPENDIX 1
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Keywords

OMERACT
RHEUMATOID ARTHRITIS
ULTRASONOGRAPHY
JUVENILE IDIOPATHIC ARTHRITIS

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OMERACT 2016 – International Consensus Conference on Outcome Measures in Rheumatology, Whistler, British Columbia, Canada, May 2016

  • An OMERACT Initiative Toward Consensus to Identify and Characterize Candidate Contextual Factors: Report from the Contextual Factors Working Group
  • Health Equity Considerations for Developing and Reporting Patient-reported Outcomes in Clinical Trials: A Report from the OMERACT Equity Special Interest Group
  • Definition and Reliability Assessment of Elementary Ultrasonographic Findings in Calcium Pyrophosphate Deposition Disease: A Study by the OMERACT Calcium Pyrophosphate Deposition Disease Ultrasound Subtask Force
Show more OMERACT 2016 – International Consensus Conference on Outcome Measures in Rheumatology, Whistler, British Columbia, Canada, May 2016

Special Interest Groups, Part 1

  • An OMERACT Initiative Toward Consensus to Identify and Characterize Candidate Contextual Factors: Report from the Contextual Factors Working Group
  • Health Equity Considerations for Developing and Reporting Patient-reported Outcomes in Clinical Trials: A Report from the OMERACT Equity Special Interest Group
  • Definition and Reliability Assessment of Elementary Ultrasonographic Findings in Calcium Pyrophosphate Deposition Disease: A Study by the OMERACT Calcium Pyrophosphate Deposition Disease Ultrasound Subtask Force
Show more Special Interest Groups, Part 1

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  • ultrasonography
  • juvenile idiopathic arthritis

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