Article Figures & Data
Figures
- Figure 1.
Boxplot of HSUV scores by measure. SF-6D, n = 211. SG, n = 222. TTO, n = 222. VAS, n = 222. HSUV: health state utility value; SF-6D: Short Form 6D; SG: standard gamble; TTO: time tradeoff; VAS: visual analog scale.
Tables
Variable Value Age, yrs, mean (SD) 50.9 (15.5) Female, % 84.30 Disease duration, yrs, mean (SD) 7.37 (7.85) Alcohol use, % 48 Marital status, married, % 58.80 Education, % Less than high school graduate 4.10 High school graduate 12.70 Postsecondary education 83.20 Income, %, US$/year < 25,000 19.90 25,000 to 50,000 16.80 50,000 to 75,000 14.90 > 75,000 48.40 Insurance type, % Private 56.70 Medicare/Medi-Cal 24.30 Medicare + private 12.40 None 1.40 Ethnicity, % White 71.70 Black/African American 6.30 Asian 12.10 More than one 2.20 Unknown 6.30 SSc type, n (%) Localized SSc 1 (0.46) Diffuse SSc 90 (41.29) Limited SSc 112 (51.38) Sine SSc 4 (2.29) Overlap 10 (4.59) SSc: systemic sclerosis.
- Table 2.
Regression coefficients and 95% CI of univariate analyses with each HSUV measure as the outcome. Values are coefficient (95% CI).
Variable SG TTO SF-6D VAS Duration, cont. 0.004 (0.0001–0.008) 0.004 (−0.001 to 0.009) 0.002 (−0.001 to 0.004) −0.001 (−0.005 to 0.002) Duration, > 1 yr* 0.015 (−0.06 to 0.089) 0.051 (−0.043 to 0.144) 0.056 (0.012–0.101) 0.008 (−0.058 to 0.075) Duration, > 2 yrs* 0.076 (0.009–0.142) 0.084 (0–0.167) 0.036 (−0.005 to 0.076) 0.033 (−0.027 to 0.092) Age, yrs −0.001 (−0.003 to 0.001) −0.001 (−0.003 to 0.002) 0.0002 (−0.001 to 0.001) −0.002 (−0.004 to −0.0001) Sex −0.037 (−0.121 to 0.046) 0.028 (−0.077 to 0.133) −0.009 (−0.058 to 0.040) 0.014 (−0.059 to 0.087) Income 0.014 (−0.013 to 0.042) 0.012 (−0.022 to 0.047) 0.031 (0.016–0.046) 0.028 (0.005–0.052) Education 0.022 (−0.003 to −0.046) 0.028 (−0.003 to 0.059) 0.018 (0.003–0.032) 0.008 (−0.015 to 0.030) SSc type† −0.089 (−0.152 to −0.026) −0.120 (−0.199 to −0.041) −0.04 (−0.076 to −0.004) −0.035 (−0.091 to 0.021) mRSS, cont. −0.005 (−0.009 to −0.002) −0.007 (−0.011 to −0.003) −0.003 (−0.005 to −0.001) −0.004 (−0.007 to 0) HAQ-DI −0.092 (−0.133 to −0.049) −0.161 (−0.212 to −0.111) −0.106 (−0.127 to −0.086) −0.106 (−0.141 to −0.070) CES-D −0.001 (−0.015 to −0.005) −0.014 (−0.020 to −0.008) −0.015 (−0.017 to 0.013) −0.015 (−0.019 to −0.011) FACIT Fatigue Scale −0.005 (−0.007 to −0.003) −0.009 (−0.011 to −0.006) −0.008 (−0.009 to −0.007) −0.007 (−0.009 to −0.005) Ethnicity −0.033 (−0.103 to 0.037) −0.038 (−0.126 to 0.050) −0.068 (−0.108 to −0.028) −0.037 (−0.099 to 0.024) Marital status** 0.019 (−0.043 to 0.081) −0.014 (−0.092 to 0.064) 0.018 (−0.018 to 0.054) 0.004 (−0.050 to 0.059) ↵* For these variables, the variable is equal to 1 if the condition is met.
↵† SSc type is equal to 0 for lcSSc and equal to 1 for dcSSc.
↵** Marital status is equal to 1 if married and 0 if otherwise. Significant data are in bold face (p < 0.05). HSUV: health state utility value; SG: standard gamble; TTO: time tradeoff; SF-6D: Short Form 6D; VAS: visual analog scale; cont.: continuous variable; SSc: systemic sclerosis; mRSS: modified Rodnan skin score; HAQ-DI: Health Assessment Questionnaire–Disability Index; CES-D: Center for Epidemiologic Studies Depression Scale; FACIT: Functional Assessment of Chronic Illness Therapy.
- Table 3.
Regression coefficients for primary and subgroup analyses with 95% CI for disease duration in multivariate analyses with each HSUV measure as the outcome. Adjusted for age, sex, mRSS, education, CES-D, and HAQ-DI.
Variables SG TTO SF-6D VAS Coeff 95% CI Coeff 95% CI Coeff 95% CI Coeff 95% CI Primary analysis Duration* 0.004 0.00004–0.007 0.0007 −0.004 to 0.005 0.001 −0.0002 to 0.003 0.002 −0.005 to 0.0009 Duration > 2 yrs** 0.072 0.010–0.138 0.072 −0.009 to 0.153 0.037 0.014–0.068 0.061 −0.017 to 0.089 Subgroup analysis Patients with dcSSc only Duration* 0.005 −0.004 to 0.014 −0.006 −0.017 to 0.004 0.002 −0.002 to 0.006 0.001 −0.005 to 0.006 Duration > 2 yrs** 0.062 −0.056 to 0.180 0.039 −0.105 to 0.183 0.033 −0.007 to 0.073 0.056 −0.021 to 0.133 Patients with lcSSc only Duration* 0.030 −0.001 to 0.007 0.003 −0.002 to 0.008 0.002 −0.00002 to 0.004 −0.003 −0.007 to 0.0003 Duration > 2 yrs** 0.109 0.029–0.188 0.118 0.015–0.220 0.061 0.018–0.104 0.038 −0.046 to 0.123 ↵* Disease duration modeled as continuous variable.
↵** Disease duration modeled as categorical variable (equal to 1 if greater than 2 yrs). Significant data are in bold face (p < 0.05). HSUV: health state utility value; mRSS: modified Rodnan skin score; CES-D: Center for Epidemiologic Studies Depression Scale; HAQ-DI: Health Assessment Questionnaire–Disability Index; SG: standard gamble; TTO: time tradeoff; SF-6D: Short Form 6D; VAS: visual analog scale; Coeff: regression coefficient; SSc: systemic sclerosis; dcSSc: diffuse cutaneous SSc; lcSSc: limited cutaneous SSc.
