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Research ArticleOMERACT 12 — International Consensus Conference on Outcome Measures in Rheumatology, Budapest, Hungary, May 7–11, 2014

Current Status of Efforts on Standardizing Magnetic Resonance Imaging of Juvenile Idiopathic Arthritis: Report from the OMERACT MRI in JIA Working Group and Health-e-Child

Charlotte M. Nusman, Lil-Sofie Ording Muller, Robert Hemke, Andrea S. Doria, Derk Avenarius, Nikolay Tzaribachev, Clara Malattia, Marion A.J. van Rossum, Mario Maas and Karen Rosendahl
The Journal of Rheumatology January 2016, 43 (1) 239-244; DOI: https://doi.org/10.3899/jrheum.141276
Charlotte M. Nusman
From the Department of Radiology, Academic Medical Center, Amsterdam, The Netherlands; Department of Pediatric Hematology, Immunology, Rheumatology and Infectious Disease, Emma Children’s Hospital, Academic Medical Center, Amsterdam, The Netherlands; Department of Radiology, Oslo University Hospital, Oslo, Norway; Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Radiology, University Hospital North Norway, Tromsø, Norway; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; Department of Pediatrics, University of Genoa, Genoa, Italy; Department of Pediatric Rheumatology, Reade Institute, location Jan van Breemen, Amsterdam, The Netherlands; Department of Clinical Medicine, K1, University of Bergen, and Department of Pediatric Radiology, Haukeland University Hospital, Bergen, Norway.
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  • For correspondence: c.m.nusman{at}amc.uva.nl
Lil-Sofie Ording Muller
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Robert Hemke
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Andrea S. Doria
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Derk Avenarius
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Nikolay Tzaribachev
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Clara Malattia
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Marion A.J. van Rossum
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Mario Maas
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Karen Rosendahl
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  • Overview of previous studies on MRI scoring methods for the wrist with arthritis in both rheumatoid arthritis and juvenile idiopathic arthritis. MRI: magnetic resonance imaging; CMC: carpometacarpal joint; T2 fat-sat/STIR: fat-saturated/short-tau inversion recovery imaging; SI: signal intensity.
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    Figure 1.

    Overview of previous studies on MRI scoring methods for the wrist with arthritis in both rheumatoid arthritis and juvenile idiopathic arthritis. MRI: magnetic resonance imaging; CMC: carpometacarpal joint; T2 fat-sat/STIR: fat-saturated/short-tau inversion recovery imaging; SI: signal intensity.

  • Area of bone depression (arrows) is visualized at baseline (a,b) and at followup (c,d) MRI scans of the wrist in a girl with JIA. At baseline both coronal T1-weighted (a) and axial T1-weighted fat-saturated MR images show an irregularity that would be scored as a bone erosion following the adult definitions. However, the followup MR images (c,d) fail to show any pathologic deterioration of the depression (i.e., synovial enhancement, enlargement of the lesion). MRI: magnetic resonance imaging; JIA: juvenile idiopathic arthritis.
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    Figure 2.

    Area of bone depression (arrows) is visualized at baseline (a,b) and at followup (c,d) MRI scans of the wrist in a girl with JIA. At baseline both coronal T1-weighted (a) and axial T1-weighted fat-saturated MR images show an irregularity that would be scored as a bone erosion following the adult definitions. However, the followup MR images (c,d) fail to show any pathologic deterioration of the depression (i.e., synovial enhancement, enlargement of the lesion). MRI: magnetic resonance imaging; JIA: juvenile idiopathic arthritis.

  • MRI of the wrist of a girl with JIA shows an area of bone depression in the trapezium (arrows) similar to that of the patient in Figure 2 at baseline (a,b). But at followup, both the coronal T1-weighted (c) and axial T1-weighted fat-saturated images depict obvious synovial enhancement in the lesion, which is suggestive of a pathologic “bone erosion.” MRI: magnetic resonance imaging; JIA: juvenile idiopathic arthritis.
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    Figure 3.

    MRI of the wrist of a girl with JIA shows an area of bone depression in the trapezium (arrows) similar to that of the patient in Figure 2 at baseline (a,b). But at followup, both the coronal T1-weighted (c) and axial T1-weighted fat-saturated images depict obvious synovial enhancement in the lesion, which is suggestive of a pathologic “bone erosion.” MRI: magnetic resonance imaging; JIA: juvenile idiopathic arthritis.

  • A schematic diagram representing the Amsterdam November Meeting in terms of conceptions beforehand, encountered problems, and current status.
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    Figure 4.

    A schematic diagram representing the Amsterdam November Meeting in terms of conceptions beforehand, encountered problems, and current status.

Tables

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    Table 1.

    MR imaging protocol.

    Preliminary statements on the MR imaging protocol for patients with JIA.
    • The coil is more important than the field strength of the MRI

    • Voxel size should be discussed and defined

    • Fat-saturated T1-weighted images with the same scan parameters before and after contrast are warranted

    • MRI: magnetic resonance imaging; JIA: juvenile idiopathic arthritis.

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The Journal of Rheumatology
Vol. 43, Issue 1
1 Jan 2016
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Current Status of Efforts on Standardizing Magnetic Resonance Imaging of Juvenile Idiopathic Arthritis: Report from the OMERACT MRI in JIA Working Group and Health-e-Child
Charlotte M. Nusman, Lil-Sofie Ording Muller, Robert Hemke, Andrea S. Doria, Derk Avenarius, Nikolay Tzaribachev, Clara Malattia, Marion A.J. van Rossum, Mario Maas, Karen Rosendahl
The Journal of Rheumatology Jan 2016, 43 (1) 239-244; DOI: 10.3899/jrheum.141276

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Current Status of Efforts on Standardizing Magnetic Resonance Imaging of Juvenile Idiopathic Arthritis: Report from the OMERACT MRI in JIA Working Group and Health-e-Child
Charlotte M. Nusman, Lil-Sofie Ording Muller, Robert Hemke, Andrea S. Doria, Derk Avenarius, Nikolay Tzaribachev, Clara Malattia, Marion A.J. van Rossum, Mario Maas, Karen Rosendahl
The Journal of Rheumatology Jan 2016, 43 (1) 239-244; DOI: 10.3899/jrheum.141276
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Keywords

JUVENILE IDIOPATHIC ARTHRITIS
MAGNETIC RESONANCE IMAGING
SCORING SYSTEMS
OMERACT

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OMERACT 12 — International Consensus Conference on Outcome Measures in Rheumatology, Budapest, Hungary, May 7–11, 2014

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Show more OMERACT 12 — International Consensus Conference on Outcome Measures in Rheumatology, Budapest, Hungary, May 7–11, 2014

Special Interest Groups II

  • OMERACT Filter Evidence Supporting the Measurement of At-work Productivity Loss as an Outcome Measure in Rheumatology Research
  • Development of a Provisional Core Domain Set for Polymyalgia Rheumatica: Report from the OMERACT 12 Polymyalgia Rheumatica Working Group
  • Remission in Rheumatoid Arthritis: Working Toward Incorporation of the Patient Perspective at OMERACT 12
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Keywords

  • juvenile idiopathic arthritis
  • magnetic resonance imaging
  • SCORING SYSTEMS
  • OMERACT

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