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Research ArticleArticle

Disease Relapses among Patients with Giant Cell Arteritis: A Prospective, Longitudinal Cohort Study

Tanaz A. Kermani, Kenneth J. Warrington, David Cuthbertson, Simon Carette, Gary S. Hoffman, Nader A. Khalidi, Curry L. Koening, Carol A. Langford, Kathleen Maksimowicz-McKinnon, Carol A. McAlear, Paul A. Monach, Philip Seo, Peter A. Merkel and Steven R. Ytterberg for the Vasculitis Clinical Research Consortium
The Journal of Rheumatology July 2015, 42 (7) 1213-1217; DOI: https://doi.org/10.3899/jrheum.141347
Tanaz A. Kermani
From the Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, Minnesota; Department of Biostatistics, University of South Florida, Tampa, Florida, USA; Division of Rheumatology, Mount Sinai Hospital, Toronto, Ontario, Canada; Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland, Ohio, USA; Division of Rheumatology, St. Joseph’s Healthcare, McMaster University, Hamilton, Ontario, Canada; Division of Rheumatology, University of Utah, Salt Lake City, Utah; Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania; The Vasculitis Center, Section of Rheumatology, Boston University School of Medicine, Boston, Massachusetts; Division of Rheumatology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; Division of Rheumatology, Johns Hopkins University, Baltimore, Maryland; University of California at Los Angeles (UCLA), Los Angeles, California, USA.
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  • For correspondence: kermani.tanaz@yahoo.com
Kenneth J. Warrington
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David Cuthbertson
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Simon Carette
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Gary S. Hoffman
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Nader A. Khalidi
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Curry L. Koening
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Carol A. Langford
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Kathleen Maksimowicz-McKinnon
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Carol A. McAlear
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Paul A. Monach
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Philip Seo
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Peter A. Merkel
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Steven R. Ytterberg
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    Figure 1.

    Relapses in 69 patients with newly diagnosed giant cell arteritis.

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    Table 1.

    Symptoms of active giant cell arteritis during all 59 relapses, and by prednisone dose at time of relapse. Values expressed as no. relapses with the symptom recorded divided by total no. relapses at that dose of prednisone (%). Steroid data were unavailable in 2 relapses.

    SymptomsAll, n = 59Prednisone, 0 mg, n =11Prednisone, 1–10 mg, n = 32Prednisone, 11–20 mg, n = 11Prednisone, > 20 mg, n = 3
    Cranial
      Headache25 (42)1 (9)12 (38)8 (73)3 (100)
      Scalp tenderness19 (32)0 (0)7 (22)9 (82)2 (67)
      New temporal artery pain6 (10)0 (0)2 (6)2 (18)2 (67)
      Carotidynia2 (3)0 (0)2 (6)0 (0)0 (0)
      Jaw/tongue claudication8 (14)1 (9)4 (13)3 (27)0 (0)
    Visual manifestations3 (5)0 (0)3 (9)0 (0)0 (0)
    PMR/arthralgia30 (51)8 (73)16 (50)5 (45)1 (33)
    Upper extremity claudication6 (10)2 (18)3 (9)0 (0)0 (0)
    Lower extremity claudication1 (2)0 (0)1 (3)0 (0)0 (0)
    Constitutional (weight loss, fatigue)8 (14)2 (18)4 (13)1 (9)1 (33)
    • PMR: polymyalgia rheumatica.

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The Journal of Rheumatology
Vol. 42, Issue 7
1 Jul 2015
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Disease Relapses among Patients with Giant Cell Arteritis: A Prospective, Longitudinal Cohort Study
Tanaz A. Kermani, Kenneth J. Warrington, David Cuthbertson, Simon Carette, Gary S. Hoffman, Nader A. Khalidi, Curry L. Koening, Carol A. Langford, Kathleen Maksimowicz-McKinnon, Carol A. McAlear, Paul A. Monach, Philip Seo, Peter A. Merkel, Steven R. Ytterberg
The Journal of Rheumatology Jul 2015, 42 (7) 1213-1217; DOI: 10.3899/jrheum.141347

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Disease Relapses among Patients with Giant Cell Arteritis: A Prospective, Longitudinal Cohort Study
Tanaz A. Kermani, Kenneth J. Warrington, David Cuthbertson, Simon Carette, Gary S. Hoffman, Nader A. Khalidi, Curry L. Koening, Carol A. Langford, Kathleen Maksimowicz-McKinnon, Carol A. McAlear, Paul A. Monach, Philip Seo, Peter A. Merkel, Steven R. Ytterberg
The Journal of Rheumatology Jul 2015, 42 (7) 1213-1217; DOI: 10.3899/jrheum.141347
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Keywords

GIANT CELL ARTERITIS
RELAPSES
DISEASE ACTIVITY
COHORT STUDY

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