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Research ArticleArticle

High Degree of Nonadherence to Disease-modifying Antirheumatic Drugs in Patients with Rheumatoid Arthritis

Veronika Rauscher, Matthias Englbrecht, Désirée van der Heijde, Georg Schett and Axel J. Hueber
The Journal of Rheumatology March 2015, 42 (3) 386-390; DOI: https://doi.org/10.3899/jrheum.140982
Veronika Rauscher
From the Department of Internal Medicine 3 and the Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany; and the Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.
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Matthias Englbrecht
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Désirée van der Heijde
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Georg Schett
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Axel J. Hueber
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  • For correspondence: axel.hueber@uk-erlangen.de
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Abstract

Objective. To test medication adherence using the Compliance-Questionnaire-Rheumatology (CQR).

Methods. Invitation letter and CQR were sent to 240 patients with rheumatoid arthritis. Followup CQR was sent 3 months later. Adherence was evaluated using CQR 80% cutoff scores.

Results. Seventy-eight patients who were being treated with disease-modifying antirheumatic drugs provided full information on the CQR at both points in time. Eleven patients (14.1%) were classified as adherent based on taking compliance (TC), with only 3 patients (3.8%) adherent in regard to correct dosing (CD) [followup: 13 (16.7%) and 3 (3.8%) for TC and CD, respectively]. Nonadherence was not related to disease activity or side effects.

Conclusion. We demonstrated low adherence, suggesting differences between doctors’ records and patients’ practice of antirheumatic drug therapy.

Key Indexing Terms:
  • ADHERENCE
  • COMPLIANCE
  • RHEUMATOID ARTHRITIS
  • CQR
  • DISEASE-MODIFYING ANTIRHEUMATIC DRUGS

Footnotes

  • Supported by the EuroTEAM consortium. This work was performed in (partial) fulfillment of the requirements for obtaining the doctoral degree Dr. med.

  • Accepted for publication November 10, 2014.
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The Journal of Rheumatology
Vol. 42, Issue 3
1 Mar 2015
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High Degree of Nonadherence to Disease-modifying Antirheumatic Drugs in Patients with Rheumatoid Arthritis
Veronika Rauscher, Matthias Englbrecht, Désirée van der Heijde, Georg Schett, Axel J. Hueber
The Journal of Rheumatology Mar 2015, 42 (3) 386-390; DOI: 10.3899/jrheum.140982

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High Degree of Nonadherence to Disease-modifying Antirheumatic Drugs in Patients with Rheumatoid Arthritis
Veronika Rauscher, Matthias Englbrecht, Désirée van der Heijde, Georg Schett, Axel J. Hueber
The Journal of Rheumatology Mar 2015, 42 (3) 386-390; DOI: 10.3899/jrheum.140982
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Keywords

ADHERENCE
COMPLIANCE
RHEUMATOID ARTHRITIS
CQR
DISEASE-MODIFYING ANTIRHEUMATIC DRUGS

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Keywords

  • ADHERENCE
  • COMPLIANCE
  • rheumatoid arthritis
  • CQR
  • disease-modifying antirheumatic drugs

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