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Research ArticleOMERACT 12 — International Consensus Conference on Outcome Measures in Rheumatology, Budapest, Hungary, May 7–11, 2014

The OMERACT Ultrasound Working Group 10 Years On: Update at OMERACT 12

George A. Bruyn, Esperanza Naredo, Annamaria Iagnocco, Peter V. Balint, Marina Backhaus, Frederique Gandjbakhch, Marwin Gutierrez, Andrew Filer, Stephanie Finzel, Kei Ikeda, Gurjit S. Kaeley, Silvia Magni Manzoni, Sarah Ohrndorf, Carlos Pineda, Bethan Richards, Johannes Roth, Wolfgang A. Schmidt, Lene Terslev and Maria Antonietta D’Agostino on behalf of the OMERACT Ultrasound Task Force
The Journal of Rheumatology November 2015, 42 (11) 2172-2176; DOI: https://doi.org/10.3899/jrheum.141462
George A. Bruyn
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  • For correspondence: gawbruyn{at}wxs.nl
Esperanza Naredo
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Annamaria Iagnocco
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Peter V. Balint
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Marina Backhaus
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Frederique Gandjbakhch
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Marwin Gutierrez
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Andrew Filer
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Stephanie Finzel
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Kei Ikeda
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Gurjit S. Kaeley
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Silvia Magni Manzoni
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Sarah Ohrndorf
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Carlos Pineda
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Bethan Richards
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Johannes Roth
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Wolfgang A. Schmidt
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Lene Terslev
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Maria Antonietta D’Agostino
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  • Article
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Article Figures & Data

Figures

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  • Categorization of candidate elements in dactylitis into domains after first round of Delphi process. Nail plate Tri Loss / Irrg: loss of nail plate trilaminar structure and/or irregularity of nail plate; Intracap calcification: intracapsular calcification; Lig: ligament; Tend.: tendon; Enth.: enthesitis.
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    Figure 1.

    Categorization of candidate elements in dactylitis into domains after first round of Delphi process. Nail plate Tri Loss / Irrg: loss of nail plate trilaminar structure and/or irregularity of nail plate; Intracap calcification: intracapsular calcification; Lig: ligament; Tend.: tendon; Enth.: enthesitis.

Tables

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    Table 1.

    US testing intraobserver and interobserver reliability on small erosions in patients with RA and healthy controls.

    IntraobserverInterobserver
    Normal BreakAbnormal BreakNormal BreakAbnormal Break
    Palmar long0.1–0.80.6–0.90.80.9
    Dorsal long0.4–0.6−0.1–0.50.40.7
    Palmar transv0.2–0.70.5–0.70.70.5
    Dorsal transv0.3–0.90.4–0.80.30.4
    • US: ultrasound; RA: rheumatoid arthritis.

    • View popup
    Table 2.

    Endorsement of 4 voting questions in the final plenary session.

    Voting QuestionEndorsement, %
    Do you agree to investigate the correlation between structural damage and inflammation and clinical outcomes in hand OA?81
    Do you agree that US can be developed as an outcome instrument in dactylitis?77
    Do you agree that an ultrasound domain core set in gout should include urate load, inflammation, and damage?76
    Following successful work on synovitis and tenosynovitis in RA, should we continue to work on erosions?76
    • OA: osteoarthritis; US: ultrasound; RA: rheumatoid arthritis.

    • View popup
    Table 3.

    Future research agenda and time line of the OMERACT US working group.

    US Research FieldOutcomeResearch Phase
    Detection of minimal erosions in RAMinimal erosionValidity studies
    Definition of an US core domain set in goutInflammation, damage, urate loadDelphi study on definitions/reliability
    Definition of an US core domain set in hand OAStructural lesionsDelphi study/reliability
    Definition of an US core domain set in PsADactylitisDelphi study
    Definition of an US core domain set in pediatric arthritisSynovitisDelphi study on normal sonoanatomy and synovitis
    • US: ultrasonography; RA: rheumatoid arthritis; OA: osteoarthritis; PsA: psoriatic arthritis.

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The Journal of Rheumatology
Vol. 42, Issue 11
1 Nov 2015
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The OMERACT Ultrasound Working Group 10 Years On: Update at OMERACT 12
George A. Bruyn, Esperanza Naredo, Annamaria Iagnocco, Peter V. Balint, Marina Backhaus, Frederique Gandjbakhch, Marwin Gutierrez, Andrew Filer, Stephanie Finzel, Kei Ikeda, Gurjit S. Kaeley, Silvia Magni Manzoni, Sarah Ohrndorf, Carlos Pineda, Bethan Richards, Johannes Roth, Wolfgang A. Schmidt, Lene Terslev, Maria Antonietta D’Agostino
The Journal of Rheumatology Nov 2015, 42 (11) 2172-2176; DOI: 10.3899/jrheum.141462

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The OMERACT Ultrasound Working Group 10 Years On: Update at OMERACT 12
George A. Bruyn, Esperanza Naredo, Annamaria Iagnocco, Peter V. Balint, Marina Backhaus, Frederique Gandjbakhch, Marwin Gutierrez, Andrew Filer, Stephanie Finzel, Kei Ikeda, Gurjit S. Kaeley, Silvia Magni Manzoni, Sarah Ohrndorf, Carlos Pineda, Bethan Richards, Johannes Roth, Wolfgang A. Schmidt, Lene Terslev, Maria Antonietta D’Agostino
The Journal of Rheumatology Nov 2015, 42 (11) 2172-2176; DOI: 10.3899/jrheum.141462
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  • Article
    • Abstract
    • A Decade Put into Historical Perspective
    • Current Research Agenda. “True Erosion,” Gout, Pediatric Arthritis, OA, and Dactylitis
    • APPENDIX
    • REFERENCES
  • Figures & Data
  • Info & Metrics
  • References
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Keywords

JOINT EROSIONS
OUTCOME ASSESSMENT
ULTRASONOGRAPHY

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OMERACT 12 — International Consensus Conference on Outcome Measures in Rheumatology, Budapest, Hungary, May 7–11, 2014

  • OMERACT Filter Evidence Supporting the Measurement of At-work Productivity Loss as an Outcome Measure in Rheumatology Research
  • Development of a Provisional Core Domain Set for Polymyalgia Rheumatica: Report from the OMERACT 12 Polymyalgia Rheumatica Working Group
  • Current Status of Efforts on Standardizing Magnetic Resonance Imaging of Juvenile Idiopathic Arthritis: Report from the OMERACT MRI in JIA Working Group and Health-e-Child
Show more OMERACT 12 — International Consensus Conference on Outcome Measures in Rheumatology, Budapest, Hungary, May 7–11, 2014

Part 2: Working Groups

  • Enhanced Patient Involvement and the Need to Revise the Core Set — Report from the Psoriatic Arthritis Working Group at OMERACT 2014
  • Connective Tissue Disease-associated Interstitial Lung Diseases (CTD-ILD) — Report from OMERACT CTD-ILD Working Group
Show more Part 2: Working Groups

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Keywords

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  • outcome assessment
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