Abstract
At the pain workshop held prior to the Outcome Measures in Rheumatology (OMERACT) 12 conference, chronic nonmalignant pain (CP) as a “disease” was discussed, in response to growing interest in this concept and in terms of the effect on the OMERACT Filter 2.0 framework. CP is often assessed as a unidimensional outcome measure; however, if CP is a disease, then outcome measures need to define the disease state and identify all its manifestations as well as its effects, as specified by Filter 2.0. The aim was to write a discussion piece, reflecting the workshop contributions and debate, as an important step in opening a dialogue around future OMERACT Filter 2.0 Framework developments.
Footnotes
Authors were funded as follows: Dr. Conaghan, in part by Arthritis Research UK; Dr. Singh, by grants from the Agency for Health Quality and Research Center for Education and Research on Therapeutics U19 HS021110, US National Institute of Arthritis and Musculoskeletal and Skin Diseases P50 AR060772 and U34 AR062891, US National Institute on Aging U01 AG018947, US National Cancer Institute U10 CA149950; by resources and use of facilities at the VA Medical Center at Birmingham, Alabama; and by research contract CE-1304-6631 from the Patient Centered Outcomes Research Institute; Dr. Choy, from the Arthritis Research UK and National Institute for Social Care and Health Research; and Dr. Kaiser, by a grant from the German Ministry of Education and Research (BMBF 01GY1326).
Financial disclosures are as follows: Dr. Singh, research grants from Takeda and Savient and consultant fees from Savient, Takeda, Regeneron, and Allergan; on the executive of OMERACT, which receives arms-length funding from 36 companies; member of the American College of Rheumatology’s Guidelines Subcommittee of the Quality of Care Committee; and member of the Veterans Affairs Rheumatology Field Advisory Committee. Dr. Choy, research grants, membership on advisory boards and speaker bureaus of Abbott Laboratories, Allergan, Amgen, AstraZeneca, BMS, Boehringer Ingelheim, Chelsea Therapeutics, Chugai Pharma, Daiichi Sankyo, Eli Lilly, Ferring Pharmaceutical, GSK, Hospita, ISIS, Jazz Pharmaceuticals, MedImmune, Merrimack Pharmaceutical, MSD, Napp, Novimmune, Novartis, Pfizer, Pierre Fabre Medicament, Regeneron, Roche, Sanofi-Aventis, Schering Plough, Synovate, Tonix, and UCB. Lee Simon: Nicox, Fidelity, Extera, Wyeth, Asahi, Sammuded, Metabolex, SarCode, Anthera, Antares, Vical, Daiichi Sankyo, Rigel, Bayer, Solace, Puretechventures, Abbott, Omeros, Jazz, Takeda, Teva, Zydus, Alder, Cephalon, Purdue, EMDSerono, Altea, Talagen, Tigenix, Agenus, Forest, Genzyme, Horizon, Pozen, ILPharma, Analgesic Solutions, Creabilis, Kowa, Array, JRX Biopharm, Imprimis, Dara, Genco, Neos, Bayer Consumer, Sanofi, Lilly, Idera, Medac, Inotec, Osteoanalgesia, and Akron.
