Article Figures & Data
Tables
- Table 1.
Comparison of baseline characteristics between patients with and those without anterior chest wall (ACW) pain (univariate analysis).
Characteristics Patients with ACW, n = 316 Patients Without ACW, n = 392 p Male sex, % 45 47 0.6 Mean age, yrs 33.6 ± 8.5 33.8 ± 8.7 0.8 Location of axial involvement since beginning Cervical spine, % 45 33 0.001 Thoracic spine, % 67 49 0.000001 Gluteal, % 78 72 0.048 Peripheral articular involvement, % 63 52 0.003 Entheses involvement, % 54 45 0.009 Diagnosis of ankylosing spondylitis at inclusion, % 47 38 0.009 ASAS criteria fulfillment at inclusion, % 72 65 0.04 ESSG criteria fulfillment at inclusion, % 82 75 0.02 Duration between SpA diagnosis and inclusion, days 272 226 0.4 Age at IBP onset, yrs 31.9 32.4 0.5 Associated conditions at inclusion Reactive arthritis, % 1.9 0.26 0.006 SAPHO syndrome, % 6 2.6 0.02 Inflammatory bowel disease, % 5.9 2.3 0.05 Activity, quality of life Patient-acceptable symptom state, % 37 45 0.04 BAS-G (0–10) 5.40 ± 2.59 4.84 ± 2.51 0.005 BASDAI (0–100) 47.4 ± 20.2 42.4 ± 18.5 0.001 ASDAS-CRP 2.63 ± 1.09 2.39 ± 0.97 0.003 BASFI (0–100) 33.5 ± 23.3 27.9 ± 21.9 0.001 Short Form-36 Physical 38.64 ± 8.95 41.04 ± 9.45 0.001 Mental 38.93 ± 11.24 41.30 ± 11.15 0.005 Health Assessment Questionnaire (0–3) 0.66 ± 0.52 0.54 ± 0.49 0.001 ASQoL 10.11 ± 4.71 8.57 ± 5.07 0.001 Clinical findings Enthesis index (0–13) 3.65 ± 3.57 1.91 ± 2.53 0.001 Articular index 5.84 ± 10.05 3.04 ± 6.82 0.001 BASMI (0–10) 2.47 ± 1.04 2.32 ± 0.97 0.04 Laboratory tests HLA-B27, % 61 55 0.15 CRP, mg/l 10.3 ± 16.8 7.8 ± 12.0 0.02 Hemoglobin, g/dl 15.3 ± 18.8 16.1 ± 17.4 0.05 Imaging Radiographic sacroiliitis*, % 54 45 0.003 mSASSS 1.17 ± 3.11 1.0 ± 2.7 0.3 -
↵* Score ≥ 1 (see text for details). CRP: C-reactive protein; BASDAI: Bath Ankylosing Spondylitis Disease Activity Index; ASDAS-CRP: Ankylosing Spondylitis Disease Activity Score (CRP based); BASFI: Bath Ankylosing Spondylitis Functional Index; BASMI: Bath Ankylosing Spondylitis Metrology Index; mSASSS: modified Stoke Ankylosing Spondylitis Spinal Score; IBP: inflammatory back pain; ASQoL: Ankylosing Spondylitis Quality of Life questionnaire; BAS-G: Bath Ankylosing Spondylitis Global Score; ASAS: Assessment of Spondyloarthritis International Society; ESSG: European Spondyloarthropathy Study Group; SpA: spondyloarthritis; SAPHO: synovitis, acne, pustolosis, hyperostosis, osteitis.
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- Table 2.
Stepwise multivariate analysis (the item “diagnosis of ankylosing spondylitis before inclusion in the study” not included in the analysis, because of its relationship with radiological sacroiliitis): significant results.
ACW Pain, n = 316 No ACW Pain, n = 392 Adjusted OR (95% CI) p Global enthesitis score (0–13) 3.65 ± 3.57 1.91 ± 2.53 1.206 (1.142–1.274) < 0.0001 For an increase of 1 unit Involvement of thoracic spine (pain), yes vs no (%) 212 (67) 192 (49) 2.204 (1.590–3.054) < 0.0001 Radiographic sacroiliac score (%) 0: normal 142 (46) 209 (55) 1: doubtful 81 (26) 75 (20) 1.7474 (1.168–2.611) 0.0066 2: established or fusion 88 (27.9) 99 (25.78) 1.648 (0.122–2.420) 0.0108 -
ACW: anterior chest wall.
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