Skip to main content

Main menu

  • Home
  • Content
    • First Release
    • Current
    • Archives
    • Collections
    • Audiovisual Rheum
    • COVID-19 and Rheumatology
  • Resources
    • Guide for Authors
    • Submit Manuscript
    • Author Payment
    • Reviewers
    • Advertisers
    • Classified Ads
    • Reprints and Translations
    • Permissions
    • Meetings
    • FAQ
    • Policies
  • Subscribers
    • Subscription Information
    • Purchase Subscription
    • Your Account
    • Terms and Conditions
  • About Us
    • About Us
    • Editorial Board
    • Letter from the Editor
    • Duncan A. Gordon Award
    • Privacy/GDPR Policy
    • Accessibility
  • Contact Us
  • JRheum Supplements
  • Services

User menu

  • My Cart
  • Log In

Search

  • Advanced search
The Journal of Rheumatology
  • JRheum Supplements
  • Services
  • My Cart
  • Log In
The Journal of Rheumatology

Advanced Search

  • Home
  • Content
    • First Release
    • Current
    • Archives
    • Collections
    • Audiovisual Rheum
    • COVID-19 and Rheumatology
  • Resources
    • Guide for Authors
    • Submit Manuscript
    • Author Payment
    • Reviewers
    • Advertisers
    • Classified Ads
    • Reprints and Translations
    • Permissions
    • Meetings
    • FAQ
    • Policies
  • Subscribers
    • Subscription Information
    • Purchase Subscription
    • Your Account
    • Terms and Conditions
  • About Us
    • About Us
    • Editorial Board
    • Letter from the Editor
    • Duncan A. Gordon Award
    • Privacy/GDPR Policy
    • Accessibility
  • Contact Us
  • Follow jrheum on Twitter
  • Visit jrheum on Facebook
  • Follow jrheum on LinkedIn
  • Follow jrheum on YouTube
  • Follow jrheum on Instagram
  • Follow jrheum on RSS
Research ArticleArticle

Are Young Women and Men with Rheumatoid Arthritis at Risk for Fragility Fractures? A Population-based Study

Shreyasee Amin, Sherine E. Gabriel, Sara J. Achenbach, Elizabeth J. Atkinson and L. Joseph Melton III
The Journal of Rheumatology October 2013, 40 (10) 1669-1676; DOI: https://doi.org/10.3899/jrheum.121493
Shreyasee Amin
From the Department of Medicine, Divisions of Rheumatology and Endocrinology, Diabetes, Metabolism and Nutrition; and Department of Health Sciences Research, Divisions of Epidemiology and Biomedical Statistics and Informatics, College of Medicine, Mayo Clinic, Rochester, MN, USA.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: amin.shreyasee@mayo.edu
Sherine E. Gabriel
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sara J. Achenbach
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Elizabeth J. Atkinson
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
L. Joseph Melton III
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • References
  • Info & Metrics
  • PDF
  • eLetters
PreviousNext
Loading

REFERENCES

  1. 1.↵
    1. Sinigaglia L,
    2. Varenna M,
    3. Girasole G,
    4. Bianchi G
    . Epidemiology of osteoporosis in rheumatic diseases. Rheum Dis Clin North Am 2006;32:631–58.
    OpenUrlCrossRefPubMed
  2. 2.↵
    1. Maricic MJ,
    2. Gluck O
    1. Amin S
    . Bone loss and fractures in rheumatoid arthritis. In: Maricic MJ, Gluck O, editors. Bone disease in rheumatology. Philadelphia: Lippincott, Williams & Wilkins;2005:73–8.
  3. 3.↵
    1. Kanis JA,
    2. Borgstrom F,
    3. De Laet C,
    4. Johansson H,
    5. Johnell O,
    6. Jonsson B,
    7. et al.
    Assessment of fracture risk. Osteoporos Int 2005;16:581–9.
    OpenUrlCrossRefPubMed
  4. 4.↵
    1. Wright NC,
    2. Lisse JR,
    3. Walitt BT,
    4. Eaton CB,
    5. Chen Z; and
    6. Women’s Health Initiative Investigators
    . Arthritis increases the risk for fractures – results from the Women’s Health Initiative. J Rheumatol 2011;38:1680–8.
    OpenUrlAbstract/FREE Full Text
  5. 5.↵
    1. Vis M,
    2. Haavardsholm EA,
    3. Boyesen P,
    4. Haugeberg G,
    5. Uhlig T,
    6. Hoff M,
    7. et al.
    High incidence of vertebral and non-vertebral fractures in the OSTRA cohort study: a 5-year follow-up study in postmenopausal women with rheumatoid arthritis. Osteoporos Int 2011;22:2413–9.
    OpenUrlCrossRefPubMed
  6. 6.↵
    1. Furuya T,
    2. Kotake S,
    3. Inoue E,
    4. Nanke Y,
    5. Yago T,
    6. Kobashigawa T,
    7. et al.
    Risk factors associated with incident clinical vertebral and nonvertebral fractures in Japanese women with rheumatoid arthritis: a prospective 54-month observational study. J Rheumatol 2007;34:303–10.
    OpenUrlAbstract/FREE Full Text
  7. 7.↵
    1. van Staa TP,
    2. Geusens P,
    3. Bijlsma JWJ,
    4. Leufkens HGM,
    5. Cooper C
    . Clinical assessment of the long-term risk of fracture in patients with rheumatoid arthritis. Arthritis Rheum 2006;54:3104–12.
    OpenUrlCrossRefPubMed
  8. 8.↵
    1. Arai K,
    2. Hanyu T,
    3. Sugitani H,
    4. Murai T,
    5. Fujisawa J,
    6. Nakazono K,
    7. et al.
    Risk factors for vertebral fracture in menopausal or postmenopausal Japanese women with rheumatoid arthritis: a cross-sectional and longitudinal study. J Bone Miner Metab 2006;24:118–24.
    OpenUrlCrossRefPubMed
  9. 9.↵
    1. Orstavik RE,
    2. Haugeberg G,
    3. Uhlig T,
    4. Mowinckel P,
    5. Falch JA,
    6. Halse JI,
    7. et al.
    Self reported non-vertebral fractures in rheumatoid arthritis and population based controls: incidence and relationship with bone mineral density and clinical variables. Ann Rheum Dis 2004;63:177–82.
    OpenUrlAbstract/FREE Full Text
  10. 10.↵
    1. Orstavik RE,
    2. Haugeberg G,
    3. Mowinckel P,
    4. Hoiseth A,
    5. Uhlig T,
    6. Falch JA,
    7. et al.
    Vertebral deformities in rheumatoid arthritis: a comparison with population-based controls. Arch Intern Med 2004;164:420–5.
    OpenUrlCrossRefPubMed
  11. 11.↵
    1. Peel NF,
    2. Moore DJ,
    3. Barrington NA,
    4. Bax DE,
    5. Eastell R
    . Risk of vertebral fracture and relationship to bone mineral density in steroid treated rheumatoid arthritis. Ann Rheum Dis 1995;54:801–6.
    OpenUrlAbstract/FREE Full Text
  12. 12.↵
    1. Cooper C,
    2. Coupland C,
    3. Mitchell M
    . Rheumatoid arthritis, corticosteroid therapy and hip fracture. Ann Rheum Dis 1995;54:49–52.
    OpenUrlAbstract/FREE Full Text
  13. 13.↵
    1. Spector TD,
    2. Hall GM,
    3. McCloskey EV,
    4. Kanis JA
    . Risk of vertebral fracture in women with rheumatoid arthritis. BMJ 1993;306:558.
    OpenUrlFREE Full Text
  14. 14.↵
    1. Delmas PD,
    2. Marin F,
    3. Marcus R,
    4. Misurski DA,
    5. Mitlak BH
    . Beyond hip: importance of other nonspinal fractures. Am J Med 2007;120:381–7.
    OpenUrlCrossRefPubMed
  15. 15.↵
    1. Myasoedova E,
    2. Crowson CS,
    3. Kremers HM,
    4. Therneau TM,
    5. Gabriel SE
    . Is the incidence of rheumatoid arthritis rising?: results from Olmsted County, Minnesota, 1955–2007. Arthritis Rheum 2010;62:1576–82.
    OpenUrlCrossRefPubMed
  16. 16.↵
    1. Tengstrand B,
    2. Hafstrom I
    . Bone mineral density in men with rheumatoid arthritis is associated with erosive disease and sulfasalazine treatment but not with sex hormones. J Rheumatol 2002;29:2299–305.
    OpenUrlAbstract/FREE Full Text
  17. 17.↵
    1. Shenstone BD,
    2. Mahmoud A,
    3. Woodward R,
    4. Elvins D,
    5. Palmer R,
    6. Ring F,
    7. et al.
    Bone mineral density in nonsteroid treated early rheumatoid arthritis. Ann Rheum Dis 1994;53:681–4.
    OpenUrlAbstract/FREE Full Text
  18. 18.↵
    1. Compston JE,
    2. Crawley EO,
    3. Evans C,
    4. O’Sullivan MM
    . Spinal trabecular bone mineral content in patients with non-steroid treated rheumatoid arthritis. Ann Rheum Dis 1988;47:660–4.
    OpenUrlAbstract/FREE Full Text
  19. 19.↵
    1. Kim SY,
    2. Schneeweiss S,
    3. Liu J,
    4. Daniel GW,
    5. Chang C-L,
    6. Garneau K,
    7. et al.
    Risk of osteoporotic fracture in a large population-based cohort of patients with rheumatoid arthritis. Arthritis Res Ther 2010;12:R154.
    OpenUrlCrossRefPubMed
  20. 20.↵
    1. El Maghraoui A,
    2. Rezqi A,
    3. Mounach A,
    4. Achemlal L,
    5. Bezza A,
    6. Ghozlani I
    . Prevalence and risk factors of vertebral fractures in women with rheumatoid arthritis using vertebral fracture assessment. Rheumatol 2010;49:1303–10.
    OpenUrlAbstract/FREE Full Text
  21. 21.↵
    1. Hooyman JR,
    2. Melton LJ 3rd.,
    3. Nelson AM,
    4. O’Fallon WM,
    5. Riggs BL
    . Fractures after rheumatoid arthritis. A population-based study. Arthritis Rheum 1984;27:1353–61.
    OpenUrlPubMed
  22. 22.↵
    1. Melton LJ 3rd.
    . History of the Rochester Epidemiology Project. Mayo Clin Proc 1996;71:266–74.
    OpenUrlCrossRefPubMed
  23. 23.↵
    1. St Sauver JL,
    2. Grossardt BR,
    3. Yawn BP,
    4. Melton LJ 3rd.,
    5. Rocca WA
    . Use of a medical records linkage system to enumerate a dynamic population over time: the Rochester epidemiology project. Am J Epidemiol 2011;173:1059–68.
    OpenUrlAbstract/FREE Full Text
  24. 24.↵
    1. Arnett FC,
    2. Edworthy SM,
    3. Bloch DA,
    4. McShane DJ,
    5. Fries JF,
    6. Cooper NS,
    7. et al.
    The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315–24.
    OpenUrlCrossRefPubMed
  25. 25.↵
    1. Gabriel SE,
    2. Crowson CS,
    3. O’Fallon WM
    . The epidemiology of rheumatoid arthritis in Rochester, Minnesota, 1955–1985. Arthritis Rheum 1999;42:415–20.
    OpenUrlCrossRefPubMed
  26. 26.↵
    1. Doran MF,
    2. Pond GR,
    3. Crowson CS,
    4. O’Fallon WM,
    5. Gabriel SE
    . Trends in incidence and mortality in rheumatoid arthritis in Rochester, Minnesota, over a forty-year period. Arthritis Rheum 2002;46:625–31.
    OpenUrlCrossRefPubMed
  27. 27.↵
    1. Crowson CS,
    2. Liang KP,
    3. Therneau TM,
    4. Kremers HM,
    5. Gabriel SE
    . Could accelerated aging explain the excess mortality in patients with seropositive rheumatoid arthritis? Arthritis Rheum 2010;62:378–82.
    OpenUrlCrossRefPubMed
  28. 28.↵
    1. Melton LJ 3rd.,
    2. Crowson CS,
    3. O’Fallon WM
    . Fracture incidence in Olmsted County, Minnesota: comparison of urban with rural rates and changes in urban rates over time. Osteoporos Int 1999;9:29–37.
    OpenUrlCrossRefPubMed
  29. 29.↵
    1. Kaplan EL,
    2. Meier P
    . Non-parametric estimation from incomplete observations. J Am Stat Assoc 1958;53:457–81.
    OpenUrlCrossRef
  30. 30.↵
    1. Gooley TA,
    2. Leisenring W,
    3. Crowley J,
    4. Storer BE
    . Estimation of failure probabilities in the presence of competing risks: new representations of old estimators. Stat Med 1999;18:695–706.
    OpenUrlCrossRefPubMed
  31. 31.↵
    1. Gray RJ
    . A class of K-sample tests for comparing the cumulative incidence of a competing risk. Ann Stat 1988;16:1141–54.
    OpenUrlCrossRef
  32. 32.↵
    1. Melton LJ 3rd.,
    2. Chrischilles EA,
    3. Cooper C,
    4. Lane AW,
    5. Riggs BL
    . Perspective. How many women have osteoporosis? J Bone Miner Res 1992;7:1005–10.
    OpenUrlCrossRefPubMed
  33. 33.↵
    1. Khosla S,
    2. Amin S,
    3. Orwoll E
    . Osteoporosis in men. Endocr Rev 2008;29:441–64.
    OpenUrlCrossRefPubMed
  34. 34.↵
    1. van Everdingen AA,
    2. Jacobs JWG,
    3. Siewertsz Van Reesema DR,
    4. Bijlsma JWJ
    . Low-dose prednisone therapy for patients with early active rheumatoid arthritis: clinical efficacy, disease-modifying properties, and side effects: a randomized, double-blind, placebo-controlled clinical trial. Ann Intern Med 2002;136:1–12.
    OpenUrlCrossRefPubMed
  35. 35.↵
    1. de Nijs RN,
    2. Jacobs JW,
    3. Bijlsma JW,
    4. Lems WF,
    5. Laan RF,
    6. Houben HH,
    7. et al.
    Prevalence of vertebral deformities and symptomatic vertebral fractures in corticosteroid treated patients with rheumatoid arthritis. Rheumatol 2001;40:1375–83.
    OpenUrlAbstract/FREE Full Text
  36. 36.↵
    1. Takayanagi H
    . Osteoimmunology and the effects of the immune system on bone. Nat Rev Rheumatol 2009;5:667–76.
    OpenUrlCrossRefPubMed
  37. 37.↵
    1. Sato K,
    2. Takayanagi H
    . Osteoclasts, rheumatoid arthritis, and osteoimmunology. Curr Opin Rheumatol 2006;18:419–26.
    OpenUrlPubMed
  38. 38.↵
    1. Clowes JA,
    2. Riggs BL,
    3. Khosla S
    . The role of the immune system in the pathophysiology of osteoporosis. Immunol Rev 2005;208:207–27.
    OpenUrlCrossRefPubMed
  39. 39.↵
    1. Laan RF,
    2. Buijs WC,
    3. Verbeek AL,
    4. Draad MP,
    5. Corstens FH,
    6. van de Putte LB,
    7. et al.
    Bone mineral density in patients with recent onset rheumatoid arthritis: influence of disease activity and functional capacity. Ann Rheum Dis 1993;52:21–6.
    OpenUrlAbstract/FREE Full Text
  40. 40.↵
    1. Sambrook PN,
    2. Eisman JA,
    3. Champion GD,
    4. Yeates MG,
    5. Pocock NA,
    6. Eberl S
    . Determinants of axial bone loss in rheumatoid arthritis. Arthritis Rheum 1987;30:721–8.
    OpenUrlCrossRefPubMed
  41. 41.↵
    1. Kaz Kaz H,
    2. Johnson D,
    3. Kerry S,
    4. Chinappen U,
    5. Tweed K,
    6. Patel S
    . Fall-related risk factors and osteoporosis in women with rheumatoid arthritis. Rheumatology 2004;43:1267–71.
    OpenUrlAbstract/FREE Full Text
  42. 42.↵
    1. Melton LJ 3rd.,
    2. Kearns AE,
    3. Atkinson EJ,
    4. Bolander ME,
    5. Achenbach SJ,
    6. Huddleston JM,
    7. et al.
    Secular trends in hip fracture incidence and recurrence. Osteoporos Int 2009;20:687–94.
    OpenUrlCrossRefPubMed
PreviousNext
Back to top

In this issue

The Journal of Rheumatology
Vol. 40, Issue 10
1 Oct 2013
  • Table of Contents
  • Table of Contents (PDF)
  • Index by Author
  • Editorial Board (PDF)
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word about The Journal of Rheumatology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Are Young Women and Men with Rheumatoid Arthritis at Risk for Fragility Fractures? A Population-based Study
(Your Name) has forwarded a page to you from The Journal of Rheumatology
(Your Name) thought you would like to see this page from the The Journal of Rheumatology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Are Young Women and Men with Rheumatoid Arthritis at Risk for Fragility Fractures? A Population-based Study
Shreyasee Amin, Sherine E. Gabriel, Sara J. Achenbach, Elizabeth J. Atkinson, L. Joseph Melton
The Journal of Rheumatology Oct 2013, 40 (10) 1669-1676; DOI: 10.3899/jrheum.121493

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

 Request Permissions

Share
Are Young Women and Men with Rheumatoid Arthritis at Risk for Fragility Fractures? A Population-based Study
Shreyasee Amin, Sherine E. Gabriel, Sara J. Achenbach, Elizabeth J. Atkinson, L. Joseph Melton
The Journal of Rheumatology Oct 2013, 40 (10) 1669-1676; DOI: 10.3899/jrheum.121493
del.icio.us logo Digg logo Reddit logo Twitter logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
    • Abstract
    • MATERIALS AND METHODS
    • RESULTS
    • DISCUSSION
    • Acknowledgment
    • Footnotes
    • REFERENCES
  • Figures & Data
  • References
  • Info & Metrics
  • PDF
  • eLetters

Keywords

RHEUMATOID ARTHRITIS
BONE FRACTURES
OSTEOPOROSIS
EPIDEMIOLOGY

Related Articles

Cited By...

More in this TOC Section

  • Vasculitis: What Have We Learned in the Last 50 Years?
  • Demographic, Lifestyle, and Serologic Risk Factors for Rheumatoid Arthritis (RA)–associated Bronchiectasis: Role of RA-related Autoantibodies
  • The Association of Illness-related Uncertainty With Mental Health in Systemic Autoimmune Rheumatic Diseases
Show more Articles

Similar Articles

Keywords

  • rheumatoid arthritis
  • BONE FRACTURES
  • OSTEOPOROSIS
  • epidemiology

Content

  • First Release
  • Current
  • Archives
  • Collections
  • Audiovisual Rheum
  • COVID-19 and Rheumatology

Resources

  • Guide for Authors
  • Submit Manuscript
  • Author Payment
  • Reviewers
  • Advertisers
  • Classified Ads
  • Reprints and Translations
  • Permissions
  • Meetings
  • FAQ
  • Policies

Subscribers

  • Subscription Information
  • Purchase Subscription
  • Your Account
  • Terms and Conditions

More

  • About Us
  • Contact Us
  • My Alerts
  • My Folders
  • Privacy/GDPR Policy
  • RSS Feeds
The Journal of Rheumatology
The content of this site is intended for health care professionals.
Copyright © 2022 by The Journal of Rheumatology Publishing Co. Ltd.
Print ISSN: 0315-162X; Online ISSN: 1499-2752
Powered by HighWire