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Research ArticleArticle
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Magnetic Resonance Arthrography of Lesser Metatarsophalangeal Joints in Patients with Rheumatoid Arthritis: Relationship to Clinical, Biomechanical, and Radiographic Variables

HEIDI J. SIDDLE, RICHARD J. HODGSON, PHILIP O’CONNOR, ANDREW J. GRAINGER, ANTHONY C. REDMOND, RICHARD J. WAKEFIELD, ELIZABETH M.A. HENSOR and PHILIP S. HELLIWELL
The Journal of Rheumatology September 2012, 39 (9) 1786-1791; DOI: https://doi.org/10.3899/jrheum.120392
HEIDI J. SIDDLE
From the Division of Rheumatic and Musculoskeletal Disease, Leeds Institute of Molecular Medicine, University of Leeds; National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, and Department of Radiology, Leeds Teaching Hospitals National Health Service (NHS) Trust, Chapel Allerton Hospital, Leeds, UK.
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  • For correspondence: h.siddle@leeds.ac.uk
RICHARD J. HODGSON
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PHILIP O’CONNOR
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ANDREW J. GRAINGER
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ANTHONY C. REDMOND
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RICHARD J. WAKEFIELD
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ELIZABETH M.A. HENSOR
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PHILIP S. HELLIWELL
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  • Figure 1.
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    Figure 1.

    Pre (a) and post (b) contrast agent short-axis images of the third metatarsophalangeal (MTP) joint demonstrating intact capsule and plantar plate (arrows). Precontrast agent short-axis image (c) of the fourth MTP joint of the same patient demonstrating a capsular tear (arrow), which is confirmed in the postcontrast agent T1 short-axis image (d) with extravasation into the soft tissue (arrow).

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    Figure 2.

    Precontrast agent sagittal and short-axis images (a) and (b) showing absent plantar plate and laterally displaced flexor tendon (arrow). Postcontrast agent T1 sagittal (c) and short-axis (d) images showing extravasation of contrast agent into the soft tissues and flexor tendon sheath (arrow) confirming an absent plantar plate.

Tables

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    Table 1.

    Demographic, clinical, biomechanical, and radiographic variables.

    Variables
    Demographics, mean (SD)
      Sex (F/M, n)11/4
      Age, yrs29.4 (9.8)
      Disease duration, yrs7.5 (9.0; range 0.2–27)
    Disease characteristics, mean (SD)
      Rheumatoid factor-positive, n11
      DAS44 (CRP, mg/l)2.71 (0.62)
      DAS44 (ESR, mm/h)2.83 (0.68)
    Patient-reported measures, mean (SD)
      VAS forefoot pain37.7 (27.2; range 8–95)
      LFISIF12.4 (2.5; range 7–16)
      LFISAP14.9 (8.7; range 3–30)
    Forefoot deformity
      Platto Structural Index Score, mean (SD)6.0 (4.1)
      Subluxation 2nd MTP joint, n8
      Subluxation 3rd MTP joint, n8
      Subluxation 4th MTP joint, n8
      Subluxation 5th MTP joint, n4
      Plantar callus 2nd MTP joint, n6
      Plantar callus 3rd MTP joint, n1
      Plantar callus 4th MTP joint, n0
      Plantar callus 5th MTP joint, n1
    Gait measures, mean (SD)
      Velocity, cm/s95.4 (29.9)
      Peak pressure 2nd MTP joint, kPa730.9 (387.6)
      Peak pressure 3rd MTP joint, kPa531.4 (211.8)
      Peak pressure 4th MTP joint, kPa248.0 (76.5)
      Peak pressure 5th MTP joint, kPa313.1 (281.75)
    Larsen score, median (IQR)
      2nd MTP joint1 (0–4)
      3rd MTP joint1 (0–4)
      4th MTP joint1 (0–3)
      5th MTP joint2 (0–3)
    • DAS: Disease Activity Score; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; VAS: visual analog scale; LFISIF: Leeds Foot Impact Scale to assess impairment and footwear; LFISAP: LFIS to assess activity and participation; MTP: metatarsophalangeal; kPa: barefoot peak pressure; IQR: interquartile range.

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    Table 2.

    Spearman’s correlation coefficients between magnetic resonance arthrography-reported pathology at the lesser metatarsophalangeal joints in patients with rheumatoid arthritis and clinical, biomechanical, and radiographic variables.

    Variablesrspn
    Disease duration0.7280.00115
    VAS−0.1220.33215
    LFISIF score−0.1620.28215
    LFISAP score−0.0020.49715
    Platto’s FF Structural Index score0.5350.02015
    Gait velocity−0.2000.23715
    Larsen score0.8180.00015
    Callus present0.5230.02315
    Subluxation present0.4860.03315
    Peak pressure0.6290.00615
    • VAS: visual analog scale; LFISIF: Leeds Foot Impact Scale to assess impairment and footwear; LFISAP: LFIS to assess activity and participation; FF: forefoot.

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    Table 3.

    Absence or focal defect of the plantar plate seen on standard magnetic resonance imaging (MRI) compared to contrast agent extravasation on MR arthrography in 28 lesser MTP joints in patients with RA.

    MR Arthrography Contrast Agent ExtravasationNo Contrast Agent ExtravasationTotal
    Standard MR
      Absence or focal defect of plantar plate14115
      Normal plantar plate4913
      Total181028
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The Journal of Rheumatology
Vol. 39, Issue 9
1 Sep 2012
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Magnetic Resonance Arthrography of Lesser Metatarsophalangeal Joints in Patients with Rheumatoid Arthritis: Relationship to Clinical, Biomechanical, and Radiographic Variables
HEIDI J. SIDDLE, RICHARD J. HODGSON, PHILIP O’CONNOR, ANDREW J. GRAINGER, ANTHONY C. REDMOND, RICHARD J. WAKEFIELD, ELIZABETH M.A. HENSOR, PHILIP S. HELLIWELL
The Journal of Rheumatology Sep 2012, 39 (9) 1786-1791; DOI: 10.3899/jrheum.120392

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Magnetic Resonance Arthrography of Lesser Metatarsophalangeal Joints in Patients with Rheumatoid Arthritis: Relationship to Clinical, Biomechanical, and Radiographic Variables
HEIDI J. SIDDLE, RICHARD J. HODGSON, PHILIP O’CONNOR, ANDREW J. GRAINGER, ANTHONY C. REDMOND, RICHARD J. WAKEFIELD, ELIZABETH M.A. HENSOR, PHILIP S. HELLIWELL
The Journal of Rheumatology Sep 2012, 39 (9) 1786-1791; DOI: 10.3899/jrheum.120392
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