Article Figures & Data
Figures
- Figure 1.
Response with certolizumab pegol (CZP) 200 mg plus methotrexate. A. Percentage of patients with DAS28 improvement < 1.2 up to Week 12 and percentage who subsequently had LDA at Year 1. B. Percentage of patients who achieved LDA at Year 1 by time to and magnitude of initial DAS28 response. LDA: low disease activity defined as DAS28(ESR) ≤ 3.2.
Tables
- Table 1.
LDA at Year 1 among patients treated with certolizumab pegol (CZP) 200 mg plus methotrexate (MTX), who failed to achieve certain DAS28 decreases within the first 12 weeks of treatment (ITT population; N = 393). LDA: low disease activity defined as DAS28(ESR) ≤ 3.2; n: number of patients not achieving a particular DAS28 threshold (row) up to a particular timepoint (column). Grey, white, and black shading indicate > 10%, 5%–10%, and < 5% probability of achieving LDA at 1 year, respectively. ITT: intent-to-treat.
- Table 2.
Probability to achieve LDA at Year 1 among patients treated with certolizumab pegol (CZP) 200 mg plus methotrexate (MTX) according to baseline DAS28 ≤ 6.34. LDA: low disease activity defined as DAS28(ESR) ≤ 3.2; n: number of patients not achieving a particular DAS28 threshold (row) up to a particular timepoint (column). Grey, white, and black shading indicate > 10%, 5%–10%, and < 5% probability of achieving LDA at 1 year, respectively.
- Table 3.
Probability to achieve LDA at Year 1 among patients treated with certolizumab pegol (CZP) 200 mg plus methotrexate (MTX) according to baseline DAS28 > 6.34 to ≤ 6.95. LDA: low disease activity defined as DAS28(ESR) ≤ 3.2; n: number of patients not achieving a particular DAS28 threshold (row) up to a particular timepoint (column). Grey, white, and black shading indicate > 10%, 5%–10%, and < 5% probability of achieving LDA at 1 year, respectively.
- Table 4.
Probability to achieve LDA at Year 1 among patients treated with certolizumab pegol (CZP) 200 mg plus methotrexate (MTX) according to baseline DAS28 > 6.95 to ≤ 7.48. LDA: low disease activity defined as DAS28(ESR) ≤ 3.2; n: number of patients not achieving a particular DAS28 threshold (row) up to a particular timepoint (column). Grey, white, and black shading indicate > 10%, 5%–10%, and < 5% probability of achieving LDA at 1 year, respectively.
- Table 5.
Probability to achieve LDA at Year 1 among patients treated with certolizumab pegol (CZP) 200 mg plus methotrexate (MTX) according to baseline DAS28 > 7.48. LDA: low disease activity defined as DAS28(ESR) ≤ 3.2; n: number of patients not achieving a particular DAS28 threshold (row) up to a particular timepoint (column). Grey, white, and black shading indicate > 10%, 5%–10%, and < 5% probability of achieving LDA at 1 year, respectively. ITT: intent-to-treat.
- Table 6.
LDA at both Years 1 and 2 among patients treated with certolizumab pegol (CZP) 200 mg plus methotrexate (MTX) who failed to achieve DAS28 decreases within the first 12 weeks of treatment (ITT population; N = 393). LDA: low disease activity defined as DAS28(ESR) ≤ 3.2; n: number of patients not achieving each DAS28 threshold (row) up to a particular timepoint (column). Grey, white, and black shading indicate > 10%, 5%–10%, and < 5% probability of achieving LDA at 1 year, respectively. ITT: intent-to-treat.
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