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LetterLetter

Subendocardial Ischemia and Myocarditis in Systemic Lupus Erythematosus Detected by Cardiac Magnetic Resonance Imaging

PAVEL GOYKHMAN, PUJA K. MEHTA, MARGO MINISSIAN, LOUISE E.J. THOMSON, DANIEL S. BERMAN, MARIKO L. ISHIMORI, DANIEL J. WALLACE, MICHAEL H. WEISMAN, CHRISANDRA L. SHUFELT and C. NOEL BAIREY MERZ
The Journal of Rheumatology February 2012, 39 (2) 448-450; DOI: https://doi.org/10.3899/jrheum.110812
PAVEL GOYKHMAN
MD
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PUJA K. MEHTA
MD
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MARGO MINISSIAN
NP
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LOUISE E.J. THOMSON
MBChB
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DANIEL S. BERMAN
MD
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MARIKO L. ISHIMORI
MD
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DANIEL J. WALLACE
MD
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MICHAEL H. WEISMAN
MD
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CHRISANDRA L. SHUFELT
MD, MS
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C. NOEL BAIREY MERZ
MD
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  • For correspondence: noel.baireymerz@cshs.org
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    Figure 1.

    First-pass perfusion images through the short axis, 2-chamber views. The images show normal myocardial enhancement at rest (B, D, F) and the circumferential area of subendocardial hypoperfusion, marked by arrows during stress (A, C). Images A and B were taken prior to evaluation; C and D during an SLE flare; and E and F after medical management. Compared to previous scans, and following antiischemic therapy, the stress perfusion image (E) does not show any areas of hypoperfusion.

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    Figure 2.

    Delayed enhancement images, 4-chamber views. B2 demonstrates interventricular patchy enhancement (arrow) on cardiac MRI performed during an SLE flare and active chest pain. Appearance is typical for myocarditis and a new finding compared to the baseline scan A, with some residual involvement after resolution of the SLE flare and medical treatment (C2). The finding of myocarditis is supported by a patchy enhancement (arrow), consistent with myocardial edema and active inflammation on T2-weighted images without fat saturation. No active inflammation is noted on a followup scan (C1).

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    Figure 3.

    Selective left coronary angiography demonstrating normal left anterior descending (LAD) and left circumflex arteries and their branches (A). Coronary reactivity testing performed with the Volcano FloWire in the mid-LAD (arrow; B) demonstrated abnormal coronary flow reserve consistent with microvascular coronary dysfunction.

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The Journal of Rheumatology
Vol. 39, Issue 2
1 Feb 2012
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Subendocardial Ischemia and Myocarditis in Systemic Lupus Erythematosus Detected by Cardiac Magnetic Resonance Imaging
PAVEL GOYKHMAN, PUJA K. MEHTA, MARGO MINISSIAN, LOUISE E.J. THOMSON, DANIEL S. BERMAN, MARIKO L. ISHIMORI, DANIEL J. WALLACE, MICHAEL H. WEISMAN, CHRISANDRA L. SHUFELT, C. NOEL BAIREY MERZ
The Journal of Rheumatology Feb 2012, 39 (2) 448-450; DOI: 10.3899/jrheum.110812

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Subendocardial Ischemia and Myocarditis in Systemic Lupus Erythematosus Detected by Cardiac Magnetic Resonance Imaging
PAVEL GOYKHMAN, PUJA K. MEHTA, MARGO MINISSIAN, LOUISE E.J. THOMSON, DANIEL S. BERMAN, MARIKO L. ISHIMORI, DANIEL J. WALLACE, MICHAEL H. WEISMAN, CHRISANDRA L. SHUFELT, C. NOEL BAIREY MERZ
The Journal of Rheumatology Feb 2012, 39 (2) 448-450; DOI: 10.3899/jrheum.110812
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