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Research ArticleArticle

Repair of Radiographic Joint Damage Following Treatment with Etanercept in Psoriatic Arthritis Is Demonstrable by 3 Radiographic Methods

LIHI EDER, VINOD CHANDRAN and DAFNA D. GLADMAN
The Journal of Rheumatology June 2011, 38 (6) 1066-1070; DOI: https://doi.org/10.3899/jrheum.100919
LIHI EDER
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VINOD CHANDRAN
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DAFNA D. GLADMAN
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  • For correspondence: dafna.gladman@utoronto.ca
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Abstract

Objective. Psoriatic arthritis (PsA) is characterized by varied radiographic features. We describe a patient with PsA with severe radiographic damage that improved significantly following treatment with etanercept. The improvement was documented by several methods of radiographic assessment.

Methods. Etanercept was introduced in September 2005. Radiographs of the hands and feet were read using 3 methods: the modified Steinbrocker method, the van der Heijde (vdH) modification of the Sharp method, and the Ratingen scoring system.

Results. In July 2009, radiographs of the hands and feet showed improvement in erosion score and joint space narrowing, while bony proliferation remained the same [43 by modified Steinbrocker, 26 by the vdH Sharp score (12 for erosions and 14 for joint space narrowing), and 56 by the Ratingen (18 for erosion and 38 for proliferation].

Conclusion. The 3 radiographic methods were useful in demonstrating improvement in joint scores. The modified Steinbrocker method, which is the simplest, was able to reveal improvement in our patient.

Key Indexing Terms:
  • PSORIATIC ARTHRITIS
  • REPAIR
  • RADIOGRAPHY
  • ANTI-TUMOR NECROSIS FACTOR AGENTS

Footnotes

  • Dr. Eder is supported by an Abbott Psoriatic Arthritis Fellowship and a Canadian Arthritis Network Fellowship; Dr. Chandran is supported by a Canadian Institutes for Health Research Clinical Research Initiative Fellowship. The Psoriatic Arthritis Program is supported by the Krembil Foundation and the Arthritis Society by a SPARCC/NRI grant.

  • Accepted for publication December 3, 2010.
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The Journal of Rheumatology
Vol. 38, Issue 6
1 Jun 2011
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Repair of Radiographic Joint Damage Following Treatment with Etanercept in Psoriatic Arthritis Is Demonstrable by 3 Radiographic Methods
LIHI EDER, VINOD CHANDRAN, DAFNA D. GLADMAN
The Journal of Rheumatology Jun 2011, 38 (6) 1066-1070; DOI: 10.3899/jrheum.100919

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Repair of Radiographic Joint Damage Following Treatment with Etanercept in Psoriatic Arthritis Is Demonstrable by 3 Radiographic Methods
LIHI EDER, VINOD CHANDRAN, DAFNA D. GLADMAN
The Journal of Rheumatology Jun 2011, 38 (6) 1066-1070; DOI: 10.3899/jrheum.100919
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