Article Figures & Data
Tables
- Table 1.
Characteristics at time of first renal biopsy for 104 patients diagnosed with lupus nephritis between 1971 and 1995.
Characteristic No. Women, n (%) 104 83 (80) Median age at time of biopsy, yrs (IQR) 104 31 (21–41) Median duration of SLE prior to biopsy, yrs (IQR) 104 0.3 (0.0–3.8) Median s-creatinine level, μmol/l (IQR) 104 98 (79–149) Median 24-h urinary protein excretion, g (IQR) 101* 4.0 (1.5–11.3) Median systolic blood pressure, mm Hg (IQR) 100* 130 (120–150) Median diastolic blood pressure, mm Hg (IQR) 100* 90 (75–95) WHO class lupus nephritis, n (%) 104 I (normal glomeruli) 1 (1.0) II (pure mesangial alterations) 18 (17.3) III (focal segmental) 12 (11.5) IV (diffuse proliferative) 61 (58.7) V (diffuse membranous) 10 (9.6) VI (advanced sclerosing) 2 (1.9) Median NIH activity index score (IQR) 104 5 (2–9) Median NIH chronicity index score (IQR) 104 2 (0–3) -
↵* Reduced number of patients due to missing data. IQR: interquartile range; WHO: World Health Organization; NIH: US National Institutes of Health.
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- Table 2.
Ratios of observed to expected events (O:E ratios) for all ischemic heart disease (IHD) diagnoses combined, angina pectoris, myocardial infarction (MI), and other diagnoses listed under the ICD-8/10 block of IHD in a cohort of 104 patients diagnosed with lupus nephritis between 1971 and 1995 and followed throughout 2006.
Diagnosis (ICD-8/10 code) Observed* O:E Ratio (95% CI) IHD (410-410/I20–25) 31 6.8 (4.6–9.7) Angina pectoris (413/I20) 11 6.0 (3.0–11) MI (410/I21) 10 7.9 (3.8–15) Other† 10 6.9 (3.3–13) - Table 3.
Ratios of observed to expected events (O:E ratios) for all ischemic heart disease (IHD) diagnoses combined according to age at first renal biopsy, age at IHD event, time from first renal biopsy (latency), calendar-year period of first renal biopsy, and renal status, respectively, in a cohort of 104 patients diagnosed with lupus nephritis between 1971 and 1995 and followed throughout 2006.
Feature Observed* O:E Ratio (95% CI) Age at first renal biopsy, yrs < 31 13 17.1 (9.1–29) ≥ 31 18 4.8 (2.8–7.5) Age at IHD event, yrs < 30 0 0.0 (0.0–142) 30–39 11 42.3 (21–76) 40–49 8 8.5 (3.6–17) 50–59 7 6.0 (2.4–12) 60+ 5 2.3 (0.8–5.5) Latency, yrs 0–4 7 7.4 (3.0–15) 5–9 10 9.5 (4.5–17) 10–14 7 6.2 (2.5–13) 15+ 7 5.0 (2.0–10) Calendar-year period of first renal biopsy 1971–79 3 4.7 (0.9–14) 1980–89 16 5.7 (3.3–9.3) 1990–95 12 10.8 (5.6–19) Renal status – ESRD 24 5.8 (3.7–8.6) + ESRD 7 19.4 (7.8–40) -
↵* Observed number of first-time hospital discharge diagnoses. ESRD: Endstage renal disease (as defined in text).
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