Article Figures & Data
Figures
- Figure 1.
Spine bone mineral apparent density standard deviation scores (BMAD SDS) in patients with oligoarticular, polyarticular, systemic, and enthesitis-arthritis JIA vs controls at first DEXA scan. Bars represent mean and 95% CI. **p < 0.005; ***p < 0.001. NS: nonsignificant.
- Figure 2.
Spine bone mineral apparent density standard deviation scores (BMAD SDS) in patients with oligoarticular, polyarticular, systemic, and enthesitis-arthritis JIA vs controls at second DEXA scan. Bars represent mean and 95% CI. **p < 0.005; ***p < 0.001. NS: non-significant.
- Figure 3.
Spine bone mineral apparent density standard deviation scores (BMAD SDS) in patients with oligoarticular, polyarticular, systemic, and enthesitis-arthritis JIA vs controls at third DEXA scan. Bars represent mean and 95% CI. **p < 0.005; ***p < 0.001. NS: non-significant.
Tables
Characteristic JIA Controls (n) p No. of patients at first DEXA (F:M) 155:64 56:24 NS Age at first DEXA, yrs ± SD 8.5 ± 3.3 8.5 ± 4.0 NS Type of JIA onset (%) Oligoarticular 105 (48) Polyarticular 61 (28) — — Systemic 20 (9) Enthesitis-related arthritis 34 (15) Age at diagnosis, yrs ± SD 5.0 ± 3.8 Oligoarticular 4.7 ± 2.7 Polyarticular 5.7 ± 3.7 — — Systemic 4.0 ± 3.4 Enthesitis-related arthritis 8.5 ± 2.7 Disease duration, yrs ± SD 3.5 ± 3.0 Oligoarticular 3.6 ± 2.9 Polyarticular 3.1 ± 3.2 — — Systemic 3.2 ± 3.1 Enthesitis-related arthritis 3.1 ± 2.6 Height (SDS) −0.6 ± 1.1 −0.1 ± 0.9 < 0.05 BMI (SDS) −0.3 ± 0.8 0.1 ± 0.7 NS BMAD L2-L4 SDS Oligoarticular −0.41 ± 0.7 0.02 ± 0.9 < 0.005 Polyarticular −0.63 ± 0.8 0.02 ± 0.9 < 0.001 Systemic −1.41 ± 0.7 0.02 ± 0.9 < 0.001 Enthesitis-related arthritis −0.09 ± 0.5 0.02 ± 0.9 NS Total −0.78 ± 1.00 0.02 ± 0.9 NS -
JIA: juvenile idiopathic arthritis; DEXA: dual energy x-ray absorptiometry; SDS: standard deviation scores; BMAD: bone mineral apparent density; BMI: body mass index; NS: nonsignificant.
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- Table 2.
Data on 89 patients with JIA longitudinally evaluated and their respective control groups, at second and third DEXA evaluation.
Characteristic JIA Controls (n) p No. of patients at second DEXA (F:M) 64:25 59:23 NS Age at second DEXA, yrs ± SD 12.1 ± 2.9 11.8 ± 3.2 NS Type of JIA onset at second and third DEXA (%) Oligoarticular 43 (48) Polyarticular 24 (27) — — Systemic 10 (11) Enthesitis-related arthritis 12 (14) Disease duration at second DEXA, yrs ± SD 7.1 ± 3.5 Oligoarticular 7.4 ± 3.6 Polyarticular 6.5 ± 3.3 — — Systemic 7.1 ± 3.6 Enthesitis-related arthritis 5.3 ± 3.1 No. of disease flares at second DEXA 1.2 ± 1.3 BMAD L2-L4 SDS at second DEXA Oligoarticular −0.52 ± 0.8 0.10 ± 0.8 < 0.005 Polyarticular −0.60 ± 0.8 0.10 ± 0.8 < 0.001 Systemic −1.19 ± 0.5 0.10 ± 0.8 < 0.001 Enthesitis-related arthritis −0.10 ± 0.8 0.10 ± 0.8 NS No. of patients at third DEXA (F:M) 64:25 56:22 NS Age at third DEXA, yrs ± SD 13.8 ± 3.2 13.4 ± 3.8 NS Disease duration at third DEXA, yrs ± SD 8.3 ± 3.4 Oligoarticular 9.1 ± 3.6 Polyarticular 8.3 ± 3.7 — — Systemic 9.0 ± 3.3 Enthesitis-related arthritis 7.4 ± 3.5 No. of disease flares at the third DEXA 1.5 ± 1.2 BMAD L2–L4 SDS at third DEXA Oligoarticular −0.46 ± 0.9 0.07 ± 0.9 < 0.005 Polyarticular −0.62 ± 0.7 0.07 ± 0.9 < 0.001 Systemic −1.11 ± 0.8 0.07 ± 0.9 < 0.001 Enthesitis-related arthritis −0.20 ± 0.9 0.07 ± 0.9 NS -
JIA: juvenile idiopathic arthritis; DEXA: dual energy x-ray absorptiometry; SDS: standard deviation scores; BMAD: bone mineral apparent density; BMI: body mass index; NS: nonsignificant.
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