Table 3.

Table 3.

Regional mean cerebral blood volume (CBV) values (ml/100 g tissue) in SLE subjects with and without lesions and healthy controls. Repeated measures (RM) ANOVA results are given for the main effects of group, hemisphere, and region for each tissue class (cerebral gray matter, white matter, subcortical gray).

Region	Group			RM ANOVA
Region	Control, mean (SD)	SLE without Lesions, mean (SD)	SLE with Lesions, mean (SD)	Main Effect	p
Cerebral gray matter				Group	< 0.001
Left hemisphere				Hemisphere	0.481
Frontal	1.85 (0.42)	2.16 (0.63)	2.06 (0.46)	Region	0.290
Parietal	1.88 (0.49)	2.23 (0.74)	2.12 (0.55)
Temporal	2.03 (0.44)	2.28 (0.64)	2.30 (0.47)
Occipital	2.01 (0.54)	2.48 (0.95)	2.29 (0.61)
Right hemisphere
Frontal	1.83 (0.42)	2.18 (0.57)	2.04 (0.45)
Parietal	1.88 (0.47)	2.15 (0.75)	2.19 (0.53)
Temporal	2.06 (0.45)	2.34 (0.62)	2.31 (0.51)
Occipital	1.86 (0.45)	2.12 (0.71)	2.24 (0.75)
Cerebral white matter				Group	< 0.001
Left hemisphere				Hemisphere	0.887
Frontal	1.23 (0.30)	1.48 (0.48)	1.50 (0.41)	Region	< 0.001
Parietal	1.30 (0.34)	1.66 (0.64)	1.55 (0.36)
Temporal	1.51 (0.40)	1.88 (0.66)	1.85 (0.43)
Occipital	1.68 (0.49)	2.16 (0.84)	1.86 (0.57)
Right hemisphere
Frontal	1.25 (0.28)	1.45 (0.45)	1.50 (0.38)
Parietal	1.37 (0.39)	1.66 (0.57)	1.62 (0.40)
Temporal	1.64 (0.45)	1.93 (0.61)	1.93 (0.48)
Occipital	1.58 (0.42)	1.90 (0.73)	1.89 (0.48)
Subcortial				Group	0.015
Left hemisphere				Hemisphere	0.6894
Globus pallidus	1.18 (0.49)	1.54 (0.88)	1.15 (0.39)	Region	< 0.001
Caudate	1.52 (0.62)	1.58 (0.84)	1.48 (0.72)
Putamen	1.35 (0.38)	1.66 (0.64)	1.47 (0.56)
Thalamus	2.14 (1.09)	2.65 (1.25)	2.71 (1.02)
Right hemisphere
Globus pallidus	1.07 (0.31)	1.46 (0.72)	1.29 (0.49)
Caudate	1.45 (0.47)	1.62 (0.77)	1.59 (0.78)
Putamen	1.34 (0.44)	1.53 (0.62)	1.47 (0.49)
Thalamus	2.31 (1.07)	2.34 (1.04)	2.58 (1.08)
Lesion			1.00 (0.39)		< 0.001^†