Article Figures & Data
Tables
Features Whole Group Women Men p No. (%) 235 (100) 96 (41) 139 (59) Mean age, yrs, ± SD 39.1 ± 11.2 41.8 ± 11.4 37.2 ± 10.7 0.75 Mean age at onset, yrs, ± SD 27.1 ± 9.8 29.7 ± 10.2 25.1 ± 9.0 0.87 Mean disease duration, yrs, ± SD 12.4 ± 9.3 12.14 ± 9.0 12.14 ± 9.5 0.94 Delay in diagnosis, yrs, ± SD 6.7 ± 7.4 7.4 ± 7.9 6.2 ± 7.1 0.78 HLA-B27, % 70.2 63.3 75.5 0.05 Peripheral arthritis, % 42.1 53.3 30.9 0.001 Enthesitis, % 50.6 64.8 36.4 0.001 Hip involvement, % 51.0 52.0 50.0 0.65 Uveitis, % 23.4 26.2 20.6 0.09 Early axial ankylosing, % 26.4 15.0 34.8 0.001 - Table 2.
Demographic and clinical features of AS patients according to radiographic progression.
Features Slow Progression Rapid Progression p No. women/men 85/88 15/47 0.001 Mean age, yrs, ± SD 37.5 ± 11.0 44.0 ± 9.4 0.07 Mean age at onset, yrs, ± SD 27.2 ± 9.7 27.5 ± 9.9 0.36 Mean disease duration, yrs, ± SD 10.6 ± 8.5 12.8 ± 8.7 0.09 Delay in diagnosis, yrs, ± SD 6.4 ± 7.1 7.8 ± 7.1 0.08 HLA-B27, % 63 86 0.005 Peripheral arthritis, % 47 21 0.001 Enthesitis, % 54 24 0.001 Hip involvement, % 53 46 0.35 Uveitis, % 20 28 0.26 Variables Mean BASRI-lumbar Score Whole Group p Men with AS p Women with AS p Women 0.97 ± 0.14 — 0.97 ± 0.14 Men 1.77 ± 0.11 < 0.0001 1.77 ± 0.11 — HLA-B27-positive 1.58 ± 0.12 1.83 ± 0.16 1.10 ± 0.18 HLA-B27-negative 0.85 ± 0.18 0.002 0.81 ± 0.32 0.006 0.90 ± 0.20 0.47 Peripheral arthritis Present 0.93 ± 0.14 1.21 ± 0.22 0.68 ± 0.16 Absent 1.78 ± 0.11 < 0.0001 2.04 ± 0.15 0.003 1.30 ± 0.16 0.011 Enthesitis Present 1.02 ± 0.18 1.42 ± 0.30 0.74 ± 0.19 Absent 1.72 ± 0.17 0.007 1.98 ± 0.21 0.13 0.98 ± 0.26 0.47 Uveitis Present 1.57 ± 0.21 2.21 ± 0.33 1.00 ± 0.25 Absent 1.41 ± 0.11 0.53 1.68 ± 0.15 0.15 1.00 ± 0.15 0.96 Hip involvement Present 1.36 ± 0.13 1.60 ± 0.19 1.00 ± 0.16 Absent 1.55 ± 0.13 0.33 1.96 ± 0.18 0.18 0.93 ± 0.18 0.65 Characteristic ß Estimate SE p 95% CI Estimate in patients with AS* Sex 0.79 0.41 0.05 1.10–4.90 HLA-B27 1.05 0.50 0.03 1.06–7.76 Absence of peripheral arthritis 1.16 0.42 0.007 0.13–0.72 Uveitis 0.67 0.42 0.11 0.85–4.49 Hip involvement −0.34 0.38 0.37 0.33–1.50 Constant −1.47 0.27 < 0.0001 In men with AS** HLA-B27 1.69 0.80 0.03 1.12–26.71 Absence of peripheral arthritis 1.01 0.53 0.05 0.12–0.90 Uveitis 1.04 0.54 0.05 1.02–8.32 Hip involvement −0.20 0.47 0.96 0.38–0.50 Constant −1.16 0.43 0.005 In women with AS*** HLA-B27 0.63 0.71 0.37 0.46–7.55 Absence of peripheral arthritis 1.42 0.76 0.05 0.05–1.02 Uveitis 0.28 0.73 0.70 0.31–3.60 Hip involvement −0.91 0.70 0.19 0.10–1.58 Constant −1.94 0.40 < 0.0001
In this issue
Determinants of Early Radiographic Progression in Ankylosing Spondylitis
