Research ArticleArticle

Increased Levels of Interleukin 33 in Sera and Synovial Fluid from Patients with Active Rheumatoid Arthritis

YASUSHI MATSUYAMA, HITOAKI OKAZAKI, HIROYUKI TAMEMOTO, HIROTAKA KIMURA, YASUYUKI KAMATA, KATSUYA NAGATANI, TAKAO NAGASHIMA, MORISADA HAYAKAWA, MASAHIRO IWAMOTO, TAKU YOSHIO, SHIN-ICHI TOMINAGA and SEIJI MINOTA
The Journal of Rheumatology January 2010, 37 (1) 18-25; DOI: https://doi.org/10.3899/jrheum.090492

REFERENCES

  1. 1.↵
    1. Schmitz J,
    2. Owyang A,
    3. Oldham E,
    4. Song Y,
    5. Murphy E,
    6. McClanahan TK,
    7. et al.
    IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 2005;23:479–90.
    OpenUrlCrossRefPubMed
  2. 2.↵
    1. Hayakawa H,
    2. Hayakawa M,
    3. Kume A,
    4. Tominaga S
    . Soluble ST2 blocks interleukin-33 signaling in allergic airway inflammation. J Biol Chem 2007;282:26369–80.
    OpenUrlAbstract/FREE Full Text
  3. 3.↵
    1. Ali S,
    2. Huber M,
    3. Kollewe C,
    4. Bischoff SC,
    5. Falk W,
    6. Martin MU
    . IL-1 receptor accessory protein is essential for IL-33-induced activation of T lymphocytes and mast cells. Proc Natl Acad Sci USA 2007;104:18660–5.
    OpenUrlAbstract/FREE Full Text
  4. 4.↵
    1. Allakhverdi Z,
    2. Smith DE,
    3. Comeau MR,
    4. Delespesse G
    . The ST2 ligand IL-33 potently activates and drives maturation of human mast cells. J Immunol 2007;179:2051–4.
    OpenUrlAbstract/FREE Full Text
  5. 5.↵
    1. Cherry WB,
    2. Yoon J,
    3. Bartemes KR,
    4. Iijima K,
    5. Kita H
    . A novel IL-1 family cytokine, IL-33, potently activates human eosinophils. J Allergy Clin Immunol 2008;121:1484–90.
    OpenUrlCrossRefPubMed
  6. 6.↵
    1. Funakoshi-Tago M,
    2. Tago K,
    3. Hayakawa M,
    4. Tominaga S,
    5. Ohshio T,
    6. Sonoda Y,
    7. et al.
    TRAF6 is a critical signal transducer in IL-33 signaling pathway. Cell Signal 2008;20:1679–86.
    OpenUrlCrossRefPubMed
  7. 7.↵
    1. Talabot-Ayer D,
    2. Lamacchia C,
    3. Gabay C,
    4. Palmer G
    . Interleukin-33 is biologically active independently of caspase-1 cleavage. J Biol Chem 2009;284:19420–6.
    OpenUrlAbstract/FREE Full Text
  8. 8.↵
    1. Cayrol C,
    2. Girard JP
    . The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1. Proc Natl Acad Sci USA 2009;106:9021–6.
    OpenUrlAbstract/FREE Full Text
  9. 9.↵
    1. Luthi AU,
    2. Cullen SP,
    3. McNeela EA,
    4. Duriez PJ,
    5. Afonina IS,
    6. Sheridan C,
    7. et al.
    Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases. Immunity 2009;31:84–98.
    OpenUrlCrossRefPubMed
  10. 10.↵
    1. Hayakawa M,
    2. Hayakawa H,
    3. Matsuyama Y,
    4. Tamemoto H,
    5. Okazaki H,
    6. Tominaga S
    . Mature interleukin-33 is produced by calpain-mediated cleavage in vivo. Biochem Biophys Res Commun 2009;387:218–22.
    OpenUrlCrossRefPubMed
  11. 11.↵
    1. Palmer G,
    2. Talabot-Ayer D,
    3. Lamacchia C,
    4. Toy D,
    5. Seemayer CA,
    6. Viatte S,
    7. et al.
    Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis. Arthritis Rheum 2009;60:738–49.
    OpenUrlCrossRefPubMed
  12. 12.↵
    1. Xu D,
    2. Jiang HR,
    3. Kewin P,
    4. Li Y,
    5. Mu R,
    6. Fraser AR,
    7. et al.
    IL-33 exacerbates antigen-induced arthritis by activating mast cells. Proc Natl Acad Sci USA 2008;105:10913–8.
    OpenUrlAbstract/FREE Full Text
  13. 13.↵
    1. Carriere V,
    2. Roussel L,
    3. Ortega N,
    4. Lacorre DA,
    5. Americh L,
    6. Aguilar L,
    7. et al.
    IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo. Proc Natl Acad Sci USA 2007;104:282–7.
    OpenUrlAbstract/FREE Full Text
  14. 14.↵
    1. Arnett FC,
    2. Edworthy SM,
    3. Bloch DA,
    4. McShane DJ,
    5. Fries JF,
    6. Cooper NS,
    7. et al.
    The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315–24.
    OpenUrlCrossRefPubMed
  15. 15.↵
    1. Altman R,
    2. Asch E,
    3. Bloch D,
    4. Bole D,
    5. Borenstein K,
    6. Brandt K,
    7. et al.
    Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Arthritis Rheum 1986;29:1039–49.
    OpenUrlCrossRefPubMed
  16. 16.↵
    1. Groom J,
    2. Kalled SL,
    3. Cutler AH,
    4. Olson C,
    5. Woodcock SA,
    6. Schneider P,
    7. et al.
    Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren’s syndrome. J Clin Invest 2002;109:59–68.
    OpenUrlCrossRefPubMed
  17. 17.↵
    1. Martins TB,
    2. Jaskowski TD,
    3. Mouritsen CL,
    4. Hill HR
    . An evaluation of the effectiveness of three immunoglobulin G (IgG) removal procedures for routine IgM serological testing. Clin Diagn Lab Immunol 1995;2:98–103.
    OpenUrlPubMed
  18. 18.↵
    1. Felson DT,
    2. Anderson JJ,
    3. Boers M,
    4. Bombardier C,
    5. Furst D,
    6. Goldsmith C,
    7. et al.
    American College of Rheumatology preliminary definition of improvement in rheumatoid arthritis. Arthritis Rheum 1995;38:727–35.
    OpenUrlCrossRefPubMed
  19. 19.↵
    1. Inoue E,
    2. Yamanaka H,
    3. Hara M,
    4. Tomatsu T,
    5. Kamatani N
    . Comparison of Disease Activity Score (DAS)28- erythrocyte sedimentation rate and DAS28- C-reactive protein threshold values. Ann Rheum Dis 2007;66:407–9.
    OpenUrlAbstract/FREE Full Text
  20. 20.↵
    1. Hamada T,
    2. Torikai M,
    3. Kuwazuru A,
    4. Tanaka M,
    5. Horai N,
    6. Fukuda T,
    7. et al.
    Extracellular high mobility group box chromosomal protein 1 is a coupling factor for hypoxia and inflammation in arthritis. Arthritis Rheum 2008;58:2675–85.
    OpenUrlCrossRefPubMed
  21. 21.↵
    1. van Hamburg JP,
    2. Mus AM,
    3. de Bruijn MJ,
    4. de Vogel L,
    5. Boon L,
    6. Cornelissen F,
    7. et al.
    GATA-3 protects against severe joint inflammation and bone erosion and reduces differentiation of Th17 cells during experimental arthritis. Arthritis Rheum 2009;60:750–9.
    OpenUrlCrossRefPubMed
  22. 22.↵
    1. Lee DM,
    2. Friend DS,
    3. Gurish MF,
    4. Benoist C,
    5. Mathis D,
    6. Brenner MB
    . Mast cells; a cellular link between autoantibodies and inflammatory arthritis. Science 2002;297:1689–92.
    OpenUrlAbstract/FREE Full Text
  23. 23.↵
    1. Carvalho RF,
    2. Ulfgren AK,
    3. Engström M,
    4. Klint E,
    5. Nilsson G
    . CD153 in rheumatoid arthritis: detection of a soluble form in serum and synovial fluid, and expression by mast cells in the rheumatic synovium. J Rheumatol 2009;36:501–7.
    OpenUrlAbstract/FREE Full Text
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