Article Figures & Data
Figures
- Figure 1.
Rates of arterial events in persons with inflammatory myopathy, by age and sex. A. Acute myocardial infarction (based on at least one hospital discharge diagnosis with ICD-9 code 410). B. Atherosclerotic cerebrovascular disease (based on at least one hospital discharge diagnosis, or 2 billing code diagnoses, for atherosclerotic cerebrovascular disease (ICD-9 codes 433–435).
Tables
- Table 1.
Crude and adjusted risk ratios (RR) for new-onset arterial thromboembolic events in persons with inflammatory myopathies.
Cases, n = 80 Controls, n = 331 Crude Adjusted* Percent Exposed RR RR 95% CI Medication exposure Glucocorticosteroids 68.8 69.8 1.0 1.5 0.7, 3.4 NSAID 35.0 26.5 1.5 0.9 0.3, 2.4 COX-2 inhibitors 7.5 8.2 0.9 1.0 0.2, 4.6 Immunomodulators 30.0 39.4 0.7 0.5 0.2, 1.0 Methotrexate 15.0 10.5 1.5 0.9 0.3, 2.3 Azathioprine 11.3 22.4 0.4 0.3 0.1, 0.8 Antimalarial agents 5.0 6.5 0.8 0.3 0.0, 1.5 Cyclophosphamide 1.3 5.5 0.2 0.1 0.0, 1.2 Comorbidity Hypertension 66.3 46.4 2.5 2.6 1.2, 5.5 Lipid disorders 18.8 16.7 1.3 2.6 1.0, 6.5 Diabetes mellitus 23.8 17.5 1.8 1.2 0.5, 3.0 Non-atherosclerotic heart disease (CHF and valve disease) 47.5 12.5 6.0 7.0 3.2, 15.2 Obesity 6.3 1.9 3.0 0.7 0.1, 4.7 Cancer 42.5 35.1 1.5 1.7 0.8, 3.4 Interstitial lung disease 5.0 10.5 0.4 0.5 0.1, 2.3 -
↵* Multivariate analyses controlled for all covariates in the table, as well as whether the diagnosis of inflammatory myopathy was initially made in hospital or billing data, and history of coagulopathy and/or exposure to aspirin, warfarin, or low molecular weight heparin. CI: confidence interval; NSAID: nonsteroidal antiinflammatory drugs; COX-2 inhibitors: cyclooxygenase-2 inhibitors; CHF: congestive heart failure.
-
In this issue
