Article Figures & Data
Tables
- Table 1.
Baseline characteristics of patients with systemic sclerosis enrolled in the Canadian Scleroderma Research Group Registry (N = 416).
Characteristic % or mean (SD) Women, % 86.3 Mean age, yrs 56.0 (12.8) Education (more than high school), % 45.2 Mean disease duration, yrs* 10.5 (8.3) Patients with diffuse skin involvement, % 35.8 Modified Rodnan skin scores (range 0–51) 10.6 (10.0) Fingertip to palm distance, centimeters 1.1 (1.8) No. of fingertip ulcers 1.3 (2.3) Shortness of breath (range 0–10) 2.1 (2.6) No. of swollen joints 0.9 (2.9) No. of tender joints 1.8 (4.4) No. of gastrointestinal symptoms (range 0–14) 3.9 (3.0) No. of tender points of fibromyalgia (range 0–18) 3.0 (5.0) SF-36 domains** Physical functioning 36.9 (11.9) Social functioning 44.2 (11.4) Role physical 40.6 (12.0) Role emotional 44.8 (12.7) Mental health 48.4 (10.6) Vitality 46.1 (10.6) Bodily pain 43.2 (9.4) General health 38.9 (10.9) SF-36 Physical Component Summary score 37.5 (11.2) - Table 2.
Correlations between SF-36 PCS scores and sociodemographic and disease related variables.
Characteristic Correlation Coefficient p Male (compared to female) 0.1818 Age −0.0519 0.0693 More than high school education vs high school or less 0.0164 Disease duration 0.0204 0.4785 Skin score −0.1326 < 0.0001 Number of fibromyalgia tender points −0.1559 < 0.0001 Fingertip to palm distance −0.1386 < 0.0001 No. of fingertip ulcers −0.0451 0.1622 Shortness of breath −0.4102 < 0.0001 No. of swollen joints −0.1578 < 0.0001 No. of tender joints −0.2039 < 0.0001 No. of gastrointestinal symptoms −0.2854 < 0.0001 - Table 3.
Final multivariate regression model to determine clinical correlates of SF-36 PCS.
Characteristic Standardized Estimates Lower CI Upper CI Age −1.59 −2.42 −0.76 Skin score −2.28 −3.10 −1.46 Shortness of breath* −5.10 −5.97 −4.23 No. of gastrointestinal symptoms* −2.64 −3.52 −1.76 No. of swollen joints* −1.74 −2.55 −0.92 -
↵* Square root transformation of variables was performed to improve fidelity to the regression assumptions. Coefficients are standardized by the standard deviations of the transformed variables in the regression (e.g., the coefficient for number of gastrointestinal symptoms is standardized by the standard deviation of the number of gastrointestinal symptoms).
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Clinical Correlates of Self-reported Physical Health Status in Systemic Sclerosis
