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Feature Total Group Positive Antibody (manufacturer method; positive and indeterminate) Negative Antibody (manufacturer method; positive and indeterminate) Positive Antibody (modified method; positive and indeterminate) Negative Antibody (modified method; positive and indeterminate) No. 50 24 26 13 37 Male/female 13/37 7/17 6/20 2/11 9/28 Age, mean yrs 57 57 56 57.5 56 Age at onset of RA, yrs 49 49 48 48 49 History of smoking (+/total) 10/43 5/19 5/24 1/13 9/37 Erosions (+/total) 9/41 3/17 6/24 2/13 7/37 ESR, mean mm/h 22 22 22 23.7 21.5 CRP, mean mg/dl 6.8 6.9 6.8 7.5 6.6 Anti-CCP, mean U 6 7.5 5.3 3.4 5.5 Therapy Prednisone 15 9 6 5 10 Plaquenil 12 5 7 4 8 Methotrexate 18 7 11 7 11 Anti-TNF 17 6 11 4 13 -
None of these differences was statistically significant.
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