Article Figures & Data
Tables
- Table 1.
Characteristics of patients with adult onset AS (AOAS) (n = 279) and juvenile onset AS (JOAS) (n = 43).
Characteristic AOAS JOAS Mean SD Median Mean SD Median Current age, yrs† 36.11 10.20 35 29.33 8.01 28 Height, cm 169.50 8.60 170 170.80 9.10 172 Weight, kg 71.80 14.20 70 67.20 12.20 66 Age at symptom onset, yrs † 25.63 7.49 24 12.67 2.90 13 Age at diagnosis, yrs† 30.70 9.42 29 21.79 5.22 22 Delay in diagnosis, yrs† 5.08 5.99 3 9.21 5.41 9 Disease duration, yrs† 10.49 8.16 8 16.81 7.88 15 Mean BASDAI†† 4.06 2.44 3.9 4.06 2.53 4.0 BASDAI-fatigue†† 5.23 3.42 5 5.36 2.94 6 BASDAI-enthesitis†† 3.61 3.41 2.5 4.06 3.68 3 ASQOL†† 9.41 6.04 10 9.82 5.53 12 BASFI†† 38.73 28.73 37.2 40.57 28.43 41.1 Gender, M/F 226/53 39/4 BASFI > 50, %†† 37.1 38.1 Marital status, % Married 69.3 54.8 Single 25.6 40.4 Divorced/widow 4.0 2.4 Living with partner 1.1 2.4 Smoking, % Never/ex-smoker 48.7 51.2 Smoker 51.3 48.8 Education, % High school or less 69.9 69.8 University or more 30.1 30.2 Positive family history for SpA, %†† 26.7 31.6 Positive family history for AS, %†† 20.7 26.3 Positive history for psoriasis, %†† 6.2 2.4 Positive history for urethritis, %†† 11.2 7.9 Positive history for inflammatory bowel disease, %†† 4.0 7.9 Current arthritis, %* 26.2 41.5 Uveitis/positive history for uveitis, %** 10.9 23.3 Only peripheral pattern at disease onset, %*** 15.1 32.6 ↵† p < 0.001, t test, JOAS vs AOAS.
↵†† No significant odds ratio even after adjustment for current age or disease duration.
↵* Unadjusted odds ratio 1.99 (95% CI 1.01–3.93).
↵** Age adjusted odds ratio 2.92 (95% CI 1.25–6.79).
↵*** Age adjusted odds ratio 3.25 (95% CI 1.51–6.98), disease duration adjusted odds ratio 2.26 (95% CI 1.07–4.76). BASDAI: Bath AS Disease Activity Index; BASFI: Bath AS Functional Index; ASQOL: AS Quality of Life Index; SpA: spondyloarthropathy.
- Table 2.
Anthropometric measurements and radiographic scoring of the juvenile onset (JOAS) and adult onset ankylosing spondylitis (AOAS) patients.
Measure AOAS JOAS OR (95% CI) Adjusted for Age OR (95% CI) Adjusted for Disease Duration Mean SD Median Mean SD Median Cervical rotation (°) 56.47 25.15 60.00 63.94 21.35 70.00 1.00 (0.99–1.02) 1.03 (1.01–1.04)* Tragus-to-wall, cm 16.86 7.04 15.00 16.55 6.99 14.75 1.04 (0.99–1.09) 0.94 (0.88–1.00) Lateral flexion, cm 9.95 5.76 9.50 10.34 5.99 10.00 0.95 (0.89–1.01) 1.08 (1.01–1.15)* Schober, cm 3.10 1.95 3.00 2.93 2.09 2.25 0.86 (0.72–1.04) 1.07 (0.90–1.29) Intermalleolar distance, cm 96.17 28.43 100.00 95.29 32.32 97.00 0.99 (0.98–1.00) 1.00 (0.99–1.02) BASMI 3.53 2.61 3.00 3.10 2.55 3.00 1.07 (0.93–1.24) 0.78 (0.66–0.92)* Chest expansion, cm 3.99 1.94 4.00 4.18 1.92 4.00 0.90 (0.75–1.09) 1.20 (1.00–1.45)* Finger-to-floor, cm 22.13 15.94 22.00 22.25 16.71 19.25 1.00 (0.98–1.03) 0.98 (0.96–1.00) mSASSS 27.09 17.42 23.00 21.96 14.65 19.00 1.08 (1.04–1.12)* SASSS 24.13 18.69 18.50 21.51 18.14 19.00 1.04 (1.01–1.07) BASRI-spine 7.99 2.19 7.50 7.56 2.05 7.00 1.43 (1.10–1.86)* BASRI-hip 0.84 0.87 1.00 1.28 1.25 1.00 0.86 (0.58–1.28) ↵* Statistically significant.
