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LetterCorrespondence

Hepatotoxicity Associated with Etanercept in Psoriatic Arthritis

ALISON M. LEAK and BLANCA RINCON-AZNAR
The Journal of Rheumatology November 2008, 35 (11) 2286-2288; DOI: https://doi.org/10.3899/jrheum.080521
ALISON M. LEAK
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  • For correspondence: alison.leak@ekht.nhs.uk
BLANCA RINCON-AZNAR
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To the Editor:

We were interested to read the recent case report on granulomatous hepatitis associated with etanercept therapy in a patient with rheumatoid arthritis (RA)1. We have also experienced hepatotoxicity with etanercept, although in a patient with psoriatic arthritis (PsA).

A 50-year-old woman had a 20-year history of pustular psoriasis and PsA including arthritis mutilans. Psoriasis had been treated with combinations of topical and systemic drugs, including retinoids. Various nonsteroidal antiinflammatory drugs and disease-modifying antirheumatic drugs (DMARD) had been poorly tolerated or not effective. Episodes of toxicity included suspected allergic reactions (ibuprofen), raised transaminases (methotrexate), renal impairment (cyclosporine), and ...

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The Journal of Rheumatology
Vol. 35, Issue 11
1 Nov 2008
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Hepatotoxicity Associated with Etanercept in Psoriatic Arthritis
ALISON M. LEAK, BLANCA RINCON-AZNAR
The Journal of Rheumatology Nov 2008, 35 (11) 2286-2288; DOI: 10.3899/jrheum.080521

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Hepatotoxicity Associated with Etanercept in Psoriatic Arthritis
ALISON M. LEAK, BLANCA RINCON-AZNAR
The Journal of Rheumatology Nov 2008, 35 (11) 2286-2288; DOI: 10.3899/jrheum.080521
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