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LetterCorrespondence

Therapeutic Effects of Alendronate on Bone Erosion and Atrophy in a Patient with Rheumatoid Arthritis and Hepatitis C Virus Infection

MAKOTO SOEJIMA, YASUSHI KAWAGUCHI, MASAKO HARA, SEIJI SAITO, NAOYUKI KAMATANI and HISASHI YAMANAKA
The Journal of Rheumatology November 2008, 35 (11) 2284-2286; DOI: https://doi.org/10.3899/jrheum.080201
MAKOTO SOEJIMA
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YASUSHI KAWAGUCHI
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  • For correspondence: y-kawa@ior.twmu.ac.jp
MASAKO HARA
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SEIJI SAITO
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NAOYUKI KAMATANI
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HISASHI YAMANAKA
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To the Editor:

Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease associated with progressive disability and serious comorbidities1. Disease modifying antirheumatic drugs (DMARD) are now widely used in patients with RA, and treatment of RA with DMARD can prevent joint destruction2. Bisphosphonates are potent inhibitors of bone resorption and are widely used for osteoporosis and corticosteroid-induced osteoporosis3 in patients with RA. A recent study showed that bisphosphonates affected inflammation as well as resorption in a rat model of arthritis4. This background led us to administer alendronate to a patient with RA.

We describe a 38-year-old Japanese man with a ...

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    The Journal of Rheumatology
    Vol. 35, Issue 11
    1 Nov 2008
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    Therapeutic Effects of Alendronate on Bone Erosion and Atrophy in a Patient with Rheumatoid Arthritis and Hepatitis C Virus Infection
    MAKOTO SOEJIMA, YASUSHI KAWAGUCHI, MASAKO HARA, SEIJI SAITO, NAOYUKI KAMATANI, HISASHI YAMANAKA
    The Journal of Rheumatology Nov 2008, 35 (11) 2284-2286; DOI: 10.3899/jrheum.080201

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    Therapeutic Effects of Alendronate on Bone Erosion and Atrophy in a Patient with Rheumatoid Arthritis and Hepatitis C Virus Infection
    MAKOTO SOEJIMA, YASUSHI KAWAGUCHI, MASAKO HARA, SEIJI SAITO, NAOYUKI KAMATANI, HISASHI YAMANAKA
    The Journal of Rheumatology Nov 2008, 35 (11) 2284-2286; DOI: 10.3899/jrheum.080201
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