Excerpt
There have been several reviews on antiphospholipid (aPL) antibodies and the kidneys (antiphospholipid syndrome nephropathy, APSN)1,2. The second review, appearing some 13 years after the first, was timely and stressed the existence of underlying renal artery stenosis and hypertension, which had been pointed out in an early case study3.
In this issue of The Journal the article by Tektonidou, et al is more than timely4, and compares renal biopsies of patients with catastrophic, primary, and systemic lupus erythematosus-related antiphospholipid syndrome for the first time. Although the presence of renal failure in patients with catastrophic APS (CAPS, Asherson’s syndrome)5 has been…
