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Abstract

The Academic Medical Center Linear Disability Score item bank: psychometric properties of a new generic disability measure in rheumatoid arthritis.

Nadine Weisscher, Carla A Wijbrandts, Rob de Haan, Cees A W Glas, Marinus Vermeulen and Paul Peter Tak
The Journal of Rheumatology June 2007, 34 (6) 1222-1228;
Nadine Weisscher
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Carla A Wijbrandts
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Rob de Haan
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Cees A W Glas
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Marinus Vermeulen
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Paul Peter Tak
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Abstract

OBJECTIVE: To determine the psychometric properties of the Academic Medical Center (AMC) Linear Disability Scale (ALDS) item bank in a population of patients with rheumatoid arthritis (RA). METHODS: 129 patients with RA completed the ALDS and Health Assessment Questionnaire Disability Index (HAQ-DI) at baseline, and after 8 and 16 weeks of anti-tumor necrosis factor-alpha treatment. Disease activity assessments at these timepoints included serum levels of C-reactive protein, Disease Activity Score 28, morning stiffness, and visual analog scales for global disease activity and fatigue. RESULTS: Reliability of the ALDS was excellent (homogeneity, Cronbach's alpha = 0.95; test-retest, intraclass correlation coefficient = 0.93). The ALDS results at baseline were strongly correlated with the HAQ-DI (r = -0.75). With regard to known group validity, both instruments discriminated between higher and lower disease activity (ALDS, p < 0.0001; HAQ-DI, p = 0.002) and between non-, moderate, and good responders (ALDS, p = 0.002; HAQ-DI, p < 0.0001), indicating that both instruments differentiate between groups. The ALDS was moderately to highly responsive to changes between baseline and after 8 weeks and 16 weeks of treatment (standardized response mean, range = 0.71-1.19). No substantial floor or ceiling effects were found. CONCLUSION: Our results show that the ALDS is a promising new instrument, with at least equivalent psychometric properties compared to the HAQ-DI. Advantages of the ALDS item bank are its linear structure and an item bank that can be adapted depending on the ability level of the patient.

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The Journal of Rheumatology
Vol. 34, Issue 6
1 Jun 2007
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The Academic Medical Center Linear Disability Score item bank: psychometric properties of a new generic disability measure in rheumatoid arthritis.
Nadine Weisscher, Carla A Wijbrandts, Rob de Haan, Cees A W Glas, Marinus Vermeulen, Paul Peter Tak
The Journal of Rheumatology Jun 2007, 34 (6) 1222-1228;

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The Academic Medical Center Linear Disability Score item bank: psychometric properties of a new generic disability measure in rheumatoid arthritis.
Nadine Weisscher, Carla A Wijbrandts, Rob de Haan, Cees A W Glas, Marinus Vermeulen, Paul Peter Tak
The Journal of Rheumatology Jun 2007, 34 (6) 1222-1228;
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