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(Personal, non-commercial use only. The Journal of Rheumatology. Copyrigh\
t \251 2004. All rights reserved.)Tj
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(toms. Nonetheless, in this setting we could not attempt to)Tj
0.0479 Tw 0 -1.2 TD
(study the duration of exposure to the CPPD crystals, or the)Tj
0.1804 Tw T*
(time interval between calcification and the occurrence of)Tj
0.0255 Tw T*
(neck pain. Still another concern with case-control studies is)Tj
0.28999 Tw T*
[(selection bias. )17.6 (W)79.9 (e)0.1 ( ar)17.7 (gued that a proper control disease)]TJ
0.0847 Tw T*
(should have similar referral patterns and be unrelated with)Tj
0.0885 Tw T*
[(CPPD deposition disease or neck pain. )17.7 (This was felt to be)]TJ
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(adequate with hospital controls in these diagnostic groups.)Tj
-0.0217 Tw T*
(Another limitation of the study is the inability to identify the)Tj
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[(type of crystals in the calcified deposits of the )17.8 (TLA. Further)]TJ
0.07091 Tw T*
(pathological studies are warranted to confirm the nature of)Tj
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[(these calcifications. )17.6 (The strengths of this study included the)]TJ
0.0928 Tw T*
(careful matching for potential confounders of this associa-)Tj
0.0112 Tc 0.36369 Tw T*
(tion. Given these limitations, these results should be)Tj
-0.00011 Tc 0.168 Tw T*
(confirmed by further research in other populations, using)Tj
0.02499 Tw T*
(study designs that minimize potential selection bias. )Tj
0.0625 Tw 1.2 -1.2 Td
[(W)79.9 (e aimed to explore the relation between CPPD crystal)]TJ
0.0154 Tc 0.3595 Tw -1.2 -1.2 Td
[(deposition disease and neck pain. )17.7 (W)80 (e)0.1 ( confirmed the)]TJ
-0.00011 Tc 0.0497 Tw T*
(frequent involvement of the cervical spine in CPPD crystal)Tj
-0.0056 Tw T*
(deposition disease and showed that the presence of calcified)Tj
0.24409 Tw T*
(deposits in the cervical spine was associated with more)Tj
0.2973 Tw T*
[(cervical pain and dysfunction. )17.7 (This association may be)]TJ
0.10001 Tw T*
(related to more advanced cervical OA, as displayed in the)Tj
0.106 Tw T*
(older patients of this group, or related to subacute inflam-)Tj
0.00481 Tc 0.3701 Tw T*
(mation caused by the CPPD crystals. Further clinical)Tj
-0.00011 Tc 0.10519 Tw T*
[(research is warranted to confirm these findings in a lar)17.7 (ger)]TJ
0.0742 Tw T*
[(prospective cohort study)64.8 (. Better awareness by clinicians of)]TJ
0.1461 Tw T*
(CPPD deposition disease as a cause of acute and chronic)Tj
0.14371 Tw T*
(neck pain should be stressed, particularly since the thera-)Tj
0.0192 Tc 0.3557 Tw T*
[(peutic approach may be dif)17.7 (ferent for these patients.)]TJ
-0.00011 Tc 0.2164 Tw T*
(Similarly to CPPD gout, it could be worthwhile to start)Tj
0.0843 Tw T*
(patients with CPPD related neck pain on antiinflammatory)Tj
0.01801 Tc 0.3569 Tw T*
(medications instead of simple analgesics or physical)Tj
-0.00011 Tc 0 Tw T*
[(therapy)64.8 (.)]TJ
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(ACKNOWLEDGMENTS )Tj
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[(W)79.9 (e are grateful to Professor Jef)17.7 (f Neil Katz for his methodological advice)]TJ
-0.02361 Tw 0 -1.25 TD
[(and critical review)64.9 (, to Donald Halstead for his writing assistance, and to Dr)54.8 (.)]TJ
0.02499 Tw T*
(Philippe Rossier for his help in recruiting clinical controls.)Tj
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(REFERENCES)Tj
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0.02499 Tw 8 0 0 8 61 229.1616 Tm
[(1.)-875.1 (Silman )54.8 (A. Calcium pyrophosphate dihydrate \(CPPD\) deposition)]TJ
1.675 -1.25 Td
[(disease. In: Silman )54.8 (A, Hochber)17.7 (g M, editors. Epidemiology of the)]TJ
T*
(rheumatic diseases. Oxford University Press; 2001:247-55.)Tj
-1.675 -1.25 Td
[(2.)-875.1 (Resnick D, Pineda C. )17.7 (V)110.8 (ertebral involvement in calcium )]TJ
1.675 -1.25 Td
(pyrophosphate dihydrate crystal deposition disease. )Tj
T*
(Radiographic-pathological correlation. Radiology 1984;153:55-60.)Tj
-1.675 -1.25 Td
[(3.)-875.1 (Richards )54.8 (AJ, Hamilton EB. Spinal changes in idiopathic )]TJ
1.675 -1.25 Td
(chondrocalcinosis articularis. Rheumatol Rehabil 1976;15:138-42.)Tj
-1.675 -1.25 Td
[(4.)-875.1 (Baba H, Maezawa )36.8 (Y)128.9 (, Kawahara N, )17.7 (T)69.9 (omita K, Furusawa N, Imura)]TJ
1.675 -1.25 Td
(S. Calcium crystal deposition in the ligamentum flavum of the)Tj
T*
(cervical spine. Spine 1993;18:2174-81.)Tj
-1.675 -1.25 Td
[(5.)-875.1 (Chausse J, Dehais J, Bourde J. Manifestations vert\216brales)]TJ
1.675 -1.25 Td
[(douloureuses et chondrocalcinose articulaire dif)17.7 (fuse. Rev Rhum)]TJ
T*
(Mal Osteoartic 1973;40:635-42.)Tj
31.325 76.921 Td
[(6.)-875.1 (Constantin )54.8 (A, Marin F)79.7 (, Bon E, Fedele M, Lagarrigue B, Bouteiller)]TJ
1.675 -1.25 Td
(G. Calcification of the transverse ligament of the atlas in )Tj
T*
[(chondrocalcinosis: computed tomography study)64.8 (. )54.8 (Ann Rheum Dis)]TJ
0 Tc 0 Tw T*
(1996;55:137-9.)Tj
-0.00011 Tc 0.02499 Tw -1.675 -1.25 Td
[(7.)-875.1 (Resnick D, Niwayama G, Goer)17.7 (gen )17.7 (TG, et al. Clinical, radiographic)]TJ
1.675 -1.25 Td
(and pathologic abnormalities in calcium pyrophosphate dihydrate)Tj
T*
(deposition disease \(CPPD\): pseudogout. Radiology 1977;122:1-15.)Tj
-1.675 -1.25 Td
[(8.)-875.1 (Reginato )54.8 (AJ, Schiapachasse )17.7 (V)128.9 (, Zmijewski CM, Schumacher HR,)]TJ
1.675 -1.25 Td
[(Fuentes C, Galdamez M. HLA)-220.2 (antigens in chondrocalcinosis and)]TJ
T*
[(ankylosing chondrocalcinosis. )54.8 (Arthritis Rheum 1979;22:928-32.)]TJ
-1.675 -1.25 Td
[(9.)-875.1 (Kakitsubata )36.8 (Y)128.9 (,)-0.1 ( Boutin RD, )17.7 (Theodorou DJ, et al. Calcium )]TJ
1.675 -1.25 Td
(pyrophosphate dihydrate crystal deposition in and around the)Tj
T*
(atlantoaxial joint: association with type 2 odontoid fractures in nine)Tj
T*
(patients. Radiology 2000;216:213-9.)Tj
-2.175 -1.25 Td
[(10.)-875.1 (Fye KH, )17.7 (W)79.9 (einstein PR, Donald F)79.7 (. Compressive cervical)]TJ
2.175 -1.25 Td
(myelopathy due to calcium pyrophosphate dihydrate deposition)Tj
T*
[(disease: report of a case and review of the literature. )54.8 (Arch Intern)]TJ
0 Tc T*
(Med 1999;159:189-93.)Tj
-0.00011 Tc -2.1381 -1.25 Td
[(1)36.8 (1)-0.1 (.)-875.1 (Omura K, Hukuda S, Matsumoto K, Katsuura )54.8 (A, Nishioka J, Imai)]TJ
2.1381 -1.25 Td
(S. Cervical myelopathy caused by calcium pyrophosphate dihydrate)Tj
T*
[(crystal deposition in facet joints. )54.8 (A)-220.1 (case report. Spine)]TJ
0 Tc 0 Tw T*
(1996;21:2372-5.)Tj
-0.00011 Tc 0.02499 Tw -2.175 -1.25 Td
[(12.)-875.1 (McCarty D, R)39.7 (yan M. Calcium pyrophosphate crystal deposition)]TJ
2.175 -1.25 Td
(disease; Pseudogout; articular chondrocalcinosis. In: McCarty D,)Tj
T*
[(Koopman )17.7 (W)91.8 (, editors. )54.8 (Arthritis and allied conditions. Lea &)]TJ
T*
(Febiger; 1993:1835.)Tj
-2.175 -1.25 Td
[(13.)-875.1 (Feise RJ, Michael Menke J. Functional rating index: a new valid)]TJ
2.175 -1.25 Td
(and reliable instrument to measure the magnitude of clinical change)Tj
T*
(in spinal conditions. Spine 2001;26:78-87.)Tj
-2.175 -1.25 Td
[(14.)-875.1 (Cote P)110.7 (,)-0.1 ( Cassidy JD, )36.8 (Y)99.8 (ong-Hing K, Sibley J, Loewy J. )54.8 (Apophysial)]TJ
2.175 -1.25 Td
(joint degeneration, disc degeneration, and sagittal curve of the)Tj
T*
(cervical spine. Can they be measured reliably on radiographs?)Tj
0 Tc T*
(Spine 1997;22:859-64.)Tj
-0.00011 Tc -2.175 -1.25 Td
[(15.)-875.1 (Dirheimer )36.8 (Y)128.9 (, Bensimon C, Christmann D, )17.7 (W)79.9 (ackenheim C.)]TJ
2.175 -1.25 Td
(Syndesmo-odontoid joint and calcium pyrophosphate dihydrate)Tj
T*
(deposition disease \(CPPD\). Neuroradiology 1983;25:319-21.)Tj
-2.175 -1.25 Td
[(16.)-875.1 (Milz S, Schluter )17.7 (T)74 (, Putz R, Moriggl B, Ralphs JR, Benjamin M.)]TJ
2.175 -1.25 Td
(Fibrocartilage in the transverse ligament of the human atlas. Spine)Tj
0 Tc 0 Tw T*
(2001;26:1765-71.)Tj
-0.00011 Tc 0.02499 Tw -2.175 -1.25 Td
[(17.)-875.1 (W)39.8 (ilkins E, Dieppe P)110.7 (,)-0.1 ( Maddison P)110.7 (, Evison G. Osteoarthritis and)]TJ
2.175 -1.25 Td
[(articular chondrocalcinosis in the elderly)64.8 (. )54.8 (Ann Rheum Dis)]TJ
0 Tc 0 Tw T*
(1983;42:280-4.)Tj
-0.00011 Tc 0.02499 Tw -2.175 -1.25 Td
[(18.)-875.1 (Makela M, Heliovaara M, Sievers K, Impivaara O, Knekt P)110.7 (,)]TJ
2.175 -1.25 Td
[(Aromaa )54.8 (A. Prevalence, determinants, and consequences of chronic)]TJ
T*
[(neck pain in Finland. )54.8 (Am J Epidemiol 1991;134:1356-67.)]TJ
-2.175 -1.25 Td
[(19.)-875.1 (Ektor)19.7 (-Andersen J, Isacsson SO, Lindgren )54.8 (A, Orbaek P)110.7 (.)-0.1 ( )17.7 (The )]TJ
2.175 -1.25 Td
[(experience of pain from the shoulder)19.7 (-neck area related to the total)]TJ
T*
[(body pain, self-experienced health and mental distress. )17.7 (The Malmo)]TJ
T*
[(Shoulder)19.7 (-Neck Study group. Pain 1999;82:289-95.)]TJ
-2.175 -1.25 Td
[(20.)-875.1 (Felson DT)73.9 (, )54.8 (Anderson JJ, Naimark )54.8 (A, Kannel )17.7 (W)91.8 (, Meenan RF)79.7 (. )17.7 (The)]TJ
2.175 -1.25 Td
(prevalence of chondrocalcinosis in the elderly and its association)Tj
T*
[(with knee osteoarthritis: the Framingham Study)64.8 (. J Rheumatol)]TJ
0 Tc 0 Tw T*
(1989;16:1241-5.)Tj
-0.00011 Tc 0.02499 Tw -2.175 -1.25 Td
[(21.)-875.1 (Ledingham J, Regan M, Jones )54.8 (A, Doherty M. Radiographic patterns)]TJ
2.175 -1.25 Td
(and associations of osteoarthritis of the knee in patients referred to)Tj
0 Tc T*
[(hospital. )54.9 (Ann Rheum Dis 1993;52:520-6.)]TJ
-0.00011 Tc -2.175 -1.25 Td
[(22.)-875.1 (Zitnan D, Sitaj S. Natural course of articular chondrocalcinosis.)]TJ
2.175 -1.25 Td
(Arthritis Rheum 1976;19 Suppl 3:363-90.)Tj
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