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Abstract

Determination of fingertip lacticemy before and after cold stimulus in patients with primary Raynaud's phenomenon and systemic sclerosis.

Mario L C Pucinelli, Sheila Fontenelle and Luís E C Andrade
The Journal of Rheumatology July 2002, 29 (7) 1401-1403;
Mario L C Pucinelli
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Sheila Fontenelle
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Luís E C Andrade
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Abstract

OBJECTIVE: Establishing a cold stimulus test based on the measurement of finger tip lacticemy (FTL) in Raynaud's phenomenon (RP). METHODS: Twenty-seven controls and 79 patients with RP [30 systemic sclerosis (SSc) and 49 isolated RP] were studied. The latter were further classified into probable primary RP (PPRP) and probable secondary RP (PSRP). FTL was determined before (pre-CS) and after (post-CS) a cold stimulus and the percentage difference was designated ACS-FTL. RESULTS: Pre-CS-FTL was marginally higher in SSc patients than in isolated RP and controls. Post-CS-FFL was significantly higher in SSc and PSRP than in PPRP and controls. SSc and PSRP patients had higher post-CS-FTL than pre-CS-FTL (positive ACS-FTL) while controls presented a negative ACS-FTL. Post-CS-FTL had a heterogeneous behavior in patients with PPRP. CONCLUSION: CS-FTL test was shown to be an easy method for evaluation of fingertip effective perfusion before and after a cold stimulus. Further studies are warranted to test its possible clinical application in discriminating between patients with SSc and controls, as well as between patients with PPRP and PSRP.

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The Journal of Rheumatology
Vol. 29, Issue 7
1 Jul 2002
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Determination of fingertip lacticemy before and after cold stimulus in patients with primary Raynaud's phenomenon and systemic sclerosis.
Mario L C Pucinelli, Sheila Fontenelle, Luís E C Andrade
The Journal of Rheumatology Jul 2002, 29 (7) 1401-1403;

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Determination of fingertip lacticemy before and after cold stimulus in patients with primary Raynaud's phenomenon and systemic sclerosis.
Mario L C Pucinelli, Sheila Fontenelle, Luís E C Andrade
The Journal of Rheumatology Jul 2002, 29 (7) 1401-1403;
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