Colchicine is a unique anti-inflammatory drug with respect to its limited clinical usefulness and
its mode of action. Colchicine is mainly indicated for the treatment and prophylaxis of gout …

Since colchicine-sensitive microtubules regulate the expression and topography of surface
glycoproteins on a variety of cells, we sought evidence that colchicine interferes with …

… Klein drafted the manuscript; Y. Molad critically revised the manuscript. Both authors approved
all versions including the final version and are responsible for the accuracy and integrity …

Objective The Trial of Etanercept and Methotrexate with Radiographic Patient Outcomes (TEMPO)
is a 3‐year, double‐blind, multicenter study evaluating the efficacy and safety of …

OBJECTIVE: To study the clinical spectrum of Behçet's disease (BD) in childhood, in comparison
to adult-onset disease. METHODS: Nineteen children, who fulfilled disease criteria up …

Objective To assess in vivo the pathologic cascade leading to fibrosis in congenital heart
block (CHB). In vitro studies suggest that CHB is initiated via apoptosis, resulting in …

OBJECTIVE: Adenosine exerts antiinflammatory effects via activation of the A3 adenosine
receptor (A3AR), a Gi protein-associated cell-surface receptor, overexpressed in synovial …

Systemic lupus erythematosus-associated irreversible organ/system damage was previously
associated with various clinical and demographic features. We analysed the Systemic …

… (y = 0.07 + 1.81~ where y is the sTNFR concentration and x is the serum creabnine
concentration; r = 0.875, P < 0.001). These findings suggest that the increase of sTNFR in SLE …

The aim of this study was to analyse pregestational and pregnancy risk factors for adverse
fetal and maternal outcome in lupus pregnancy. Twenty women with systemic lupus …