… lines are collected and stored, and subject to strict quality control and safety measures. Coded
… to the discovery of most of the 37 genetic associations now known to contribute to lupus …

Objective B cells are likely to contribute to the pathogenesis of systemic lupus erythematosus
(SLE), and rituximab induces depletion of B cells. The Exploratory Phase II/III SLE …

… To begin to determine whether the observed histological structures were functional (48), we
determined whether … To test this directly, we used LCM coupled to RT-PCR and sequencing …

… By successfully identifying inflammatory features that define prognosis, we might be able
to identify high-risk patients prior to the onset of irreversible scarring and develop novel …

… This study was undertaken to detect associations between clinical and serologic disease
manifestations and serum IFNα activity in a large diverse SLE cohort, using multivariate and …

… Furthermore, if they are, no methods exist to determine whether they commonly provide help
to co-resident B cells in situ. To address these limitations, and to understand the function of …

… Because there are limitations to these tools that restrict their generalizibility to US
patients with SLE (17), we have developed a disease-targeted PRO measure for SLE (Lupus-PRO). …

… This study was undertaken to determine whether variants of IRF7 act as risk factors for SLE
by increasing IFNα production and whether autoantibodies are important to this phenomenon…

… To be included as a case in this study, subjects needed to have … To confirm that our results
were not due to biases in the … enrichment in our case subjects to that in different control groups…

… To obtain the best experience, we recommend you use a more up to date browser (or turn
off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we …