Peroxisome proliferator-activated receptor γ (PPARγ) is a lipid-activated transcription factor
regulating lipid metabolism and inflammatory response in macrophages and dendritic cells (…

The molecular basis of signal-dependent transcriptional activation has been extensively
studied in macrophage polarization, but our understanding remains limited regarding the …

… system (Dako) was used to visualize the labeling according to manufacturer’s instructions. …
(s) may occur during differentiation or whether it is restricted to the maturation phase in vivo. …

Gene expression profiling in clinical genomics has yet to deliver robust and reliable
approaches for developing diagnostics and contributing to personalized medicine. Owing to …

Macrophage gene expression determines phagocyte responses and effector functions.
Macrophage plasticity has been mainly addressed in in vitro models that do not account for the …

… Tissues suffer damage during an organism’s lifetime. In order to maintain the body’s … and
total RNA was isolated with TRIZOL reagent according to the manufacturer’s recommendation. …

Macrophages polarize into distinct phenotypes in response to complex environmental cues.
We found that the nuclear receptor PPARγ drove robust phenotypic changes in …

… by the addition of urea (5.2 M final concentration) and samples were reduced using tris(2-carboxyethyl)phosphine
(TCEP) in 10 mM final concentration and alkylated by 15 mM S-methyl …

… miRNA expression profiles in SLE and primary Sjögren’s syndrome, but we were the first to
compare … In conclusion, the observed differences in miRNA expression profiles in Sjögren’s …

Megakaryocyte (MK)-derived miRNAs have been detected in platelets. Here, we analysed
the expression of platelet and circulating miR-223, miR-26b, miR-126 and miR-140 that might …