[HTML][HTML] TGF-beta1 on osteoimmunology and the bone component cells

S Kasagi, W Chen - Cell & Bioscience, 2013 - Springer
TGF-β1 is an immunoregulatory cytokine that regulates immune cell proliferation, survival,
differentiation, and migration. Compelling evidence has demonstrated a strong association …

Proteasome assembly defect due to a proteasome subunit beta type 8 (PSMB8) mutation causes the autoinflammatory disorder, Nakajo-Nishimura syndrome

…, S Kasagi, S Kawano, S Kumagai… - Proceedings of the …, 2011 - National Acad Sciences
… Different varieties of electroconductive wood are widely reported; however, modulating the
wood’s ...The nature of mass transport in plants has recently inspired the development of low-…

D-mannose induces regulatory T cells and suppresses immunopathology

D Zhang, C Chia, X Jiao, W Jin, S Kasagi, R Wu… - Nature medicine, 2017 - nature.com
D-mannose, a C-2 epimer of glucose, exists naturally in many plants and fruits, and is found
in human blood at concentrations less than one-fiftieth of that of glucose. However, although …

[HTML][HTML] Antibiotics in neonatal life increase murine susceptibility to experimental psoriasis

P Zanvit, JE Konkel, X Jiao, S Kasagi, D Zhang… - Nature …, 2015 - nature.com
… The images or other third party material in this article are included in the article’s Creative
Commons license, unless indicated otherwise in the credit line; if the material is not included …

Anti-programmed cell death 1 antibody reduces CD4+ PD-1+ T cells and relieves the lupus-like nephritis of NZB/W F1 mice

S Kasagi, S Kawano, T Okazaki, T Honjo… - The Journal of …, 2010 - journals.aai.org
… Several reports, including ours on the synovitis of rheumatoid arthritis and the sialoadenitis
of Sjögren’s syndrome, show that PD-1 + T cells accumulate at sites of inflammation in …

Effects of nicotine on cultured cells suggest that it can influence the formation and resorption of bone

S Yuhara, S Kasagi, A Inoue, E Otsuka, S Hirose… - European journal of …, 1999 - Elsevier
The acute effects of nicotine [1-methyl-2-(3-pyridyl)pyrrolidine] on the formation and resorption
of bone were examined in cultures of clonal rat calvarial osteogenic cells (ROB-C26) and …

Manipulating regulatory T cells: a promising strategy to treat autoimmunity

D Zhang, E Tu, S Kasagi, P Zanvit, Q Chen… - Immunotherapy, 2015 - Future Medicine
CD4 + CD25 + Foxp3 + regulatory T cells (Treg cells) are extremely important in maintaining
immune tolerance. Manipulation of Treg cells, especially autoantigen-specific Treg cells is a …

PD-1 and autoimmunity

S Kasagi, S Kawano, S Kumagai - Critical Reviews™ in …, 2011 - dl.begellhouse.com
… While PD-L1 and PD-L2 bind PD-1 with comparable affinities, PD-L1’s dissociation is
delayed, and PD-L2’s is not. This mechanism is not restricted to PD-1 binding, since PD-L1 …

In vivo–generated antigen-specific regulatory T cells treat autoimmunity without compromising antibacterial immune response

S Kasagi, P Zhang, L Che, B Abbatiello… - Science translational …, 2014 - science.org
… For isolation of CD11b + cells (MΦ) and CD11c + cells (DCs), spleens were incubated for
20 min at 37C in a Dulbecco’s modified Eagle’s medium including collagenase (8 mg/ml) …

[HTML][HTML] The utility of galactomannan antigen in the bronchial washing and serum for diagnosing pulmonary aspergillosis

…, A Fujiwara, S Sugiyama, Y Togashi, S Kasagi… - Respiratory …, 2013 - Elsevier
Background The diagnosis of pulmonary aspergillosis is difficult because the sensitivity of the
conventional methods for the detection of Aspergillus such as culture and cytology, is poor. …